metformin has been researched along with Female Genital Neoplasms in 9 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Diabetes mellitus is associated with an elevation in gynecologic cancer risk." | 2.53 | Diabetes mellitus and gynecologic cancer: molecular mechanisms, epidemiological, clinical and prognostic perspectives. ( Alexandrou, A; Botsis, D; Creatsas, G; Grigoriadis, C; Iavazzo, C; Iliodromiti, Z; Sifakis, S; Siristatidis, C; Vrachnis, N, 2016) |
| "Metformin is an affordable and well-tolerated drug used in type 2 diabetes." | 1.56 | Metformin in Gynecologic Cancers: Opening a New Window for Prevention and Treatment? ( Goodwin, PJ; Madariaga, A; Oza, AM, 2020) |
| "Metformin has antitumor activity in monotherapy and also synergistically with other anticancer agents." | 1.39 | [Metformin--new treatment strategies for gynecologic neoplasms]. ( Kiałka, M; Krzysiek, J; Milewicz, T; Mrozińska, S; Ociepka, A, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (66.67) | 24.3611 |
| 2020's | 3 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Barczyński, B | 1 |
| Frąszczak, K | 1 |
| Kotarski, J | 1 |
| Ushijima, K | 1 |
| Tsuda, N | 1 |
| Yamagami, W | 1 |
| Mitsuhashi, A | 1 |
| Mikami, M | 1 |
| Yaegashi, N | 1 |
| Enomoto, T | 1 |
| Madariaga, A | 1 |
| Goodwin, PJ | 1 |
| Oza, AM | 1 |
| Wen, Q | 1 |
| Zhao, Z | 1 |
| Wen, J | 1 |
| Zhou, J | 1 |
| Wu, J | 1 |
| Lei, S | 1 |
| Miao, Y | 1 |
| Milewicz, T | 1 |
| Kiałka, M | 1 |
| Mrozińska, S | 1 |
| Ociepka, A | 1 |
| Krzysiek, J | 1 |
| Febbraro, T | 1 |
| Lengyel, E | 1 |
| Romero, IL | 1 |
| Banno, K | 1 |
| Iida, M | 1 |
| Yanokura, M | 1 |
| Irie, H | 1 |
| Masuda, K | 1 |
| Kobayashi, Y | 1 |
| Tominaga, E | 1 |
| Aoki, D | 1 |
| Vrachnis, N | 1 |
| Iavazzo, C | 1 |
| Iliodromiti, Z | 1 |
| Sifakis, S | 1 |
| Alexandrou, A | 1 |
| Siristatidis, C | 1 |
| Grigoriadis, C | 1 |
| Botsis, D | 1 |
| Creatsas, G | 1 |
| Hwang, JY | 1 |
5 reviews available for metformin and Female Genital Neoplasms
| Article | Year |
|---|---|
Perspectives of metformin use in endometrial cancer and other gynaecological malignancies.
Topics: Diabetes Mellitus, Type 2; Endometrial Neoplasms; Female; Genital Neoplasms, Female; Humans; Hypogly | 2022 |
The association between metformin therapy and risk of gynecological cancer in patients: Two meta-analyses.
Topics: Diabetes Mellitus, Type 2; Female; Genital Neoplasms, Female; Humans; Incidence; Metformin; Protecti | 2019 |
Old drug, new trick: repurposing metformin for gynecologic cancers?
Topics: Female; Genital Neoplasms, Female; Humans; Metformin | 2014 |
Drug repositioning for gynecologic tumors: a new therapeutic strategy for cancer.
Topics: AMP-Activated Protein Kinases; Cyclooxygenase 2 Inhibitors; Drug Repositioning; Drug Therapy, Combin | 2015 |
Diabetes mellitus and gynecologic cancer: molecular mechanisms, epidemiological, clinical and prognostic perspectives.
Topics: Diabetes Complications; Diabetes Mellitus; Energy Metabolism; Female; Genital Neoplasms, Female; Hum | 2016 |
4 other studies available for metformin and Female Genital Neoplasms
| Article | Year |
|---|---|
Trends and characteristics of fertility-sparing treatment for atypical endometrial hyperplasia and endometrial cancer in Japan: a survey by the Gynecologic Oncology Committee of the Japan Society of Obstetrics and Gynecology.
Topics: Carcinoma, Endometrioid; Endometrial Hyperplasia; Endometrial Neoplasms; Female; Fertility Preservat | 2023 |
Metformin in Gynecologic Cancers: Opening a New Window for Prevention and Treatment?
Topics: Diabetes Mellitus, Type 2; Everolimus; Female; Genital Neoplasms, Female; Humans; Letrozole; Metform | 2020 |
[Metformin--new treatment strategies for gynecologic neoplasms].
Topics: Antineoplastic Agents; Drug Synergism; Female; Genital Neoplasms, Female; Humans; Lactoylglutathione | 2013 |
Protective and therapeutic effects of metformin on gynecologic cancers.
Topics: Diabetes Mellitus, Type 2; Female; Genital Neoplasms, Female; Humans; Metformin | 2016 |