metformin and Essential Hypertension studies

Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.

Essential Hypertension: Hypertension that occurs without known cause, or preexisting renal disease. Associated polymorphisms for a number of genes have been identified, including AGT, GNB3, and ECE1. OMIM: 145500

Research Excerpts

Excerpt	Relevance	Reference
"To explore the effects of metformin on left ventricular remodeling in patients with primary hypertension and type 2 diabetes mellitus, and to investigate the effects of hypertension duration and duration of drug administration on metformin's cardiac action."	7.81	[Effect of metformin on ventricular remodeling in patients with primary hypertension and type 2 diabetes mellitus]. ( Feng, X; Gao, W; Li, Z; Wu, Y; Zhang, Y; Zhao, W, 2015)
"To explore the effects of metformin on left ventricular remodeling in patients with primary hypertension and type 2 diabetes mellitus, and to investigate the effects of hypertension duration and duration of drug administration on metformin's cardiac action."	3.81	[Effect of metformin on ventricular remodeling in patients with primary hypertension and type 2 diabetes mellitus]. ( Feng, X; Gao, W; Li, Z; Wu, Y; Zhang, Y; Zhao, W, 2015)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (100.00)	24.3611
2020's	0 (0.00)	2.80

metformin and Essential Hypertension

Research Excerpts

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