metformin has been researched along with Epilepsy, Temporal Lobe in 3 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Epilepsy, Temporal Lobe: A localization-related (focal) form of epilepsy characterized by recurrent seizures that arise from foci within the TEMPORAL LOBE, most commonly from its mesial aspect. A wide variety of psychic phenomena may be associated, including illusions, hallucinations, dyscognitive states, and affective experiences. The majority of complex partial seizures (see EPILEPSY, COMPLEX PARTIAL) originate from the temporal lobes. Temporal lobe seizures may be classified by etiology as cryptogenic, familial, or symptomatic. (From Adams et al., Principles of Neurology, 6th ed, p321).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metformin was orally administered for two weeks before induction of epilepsy." | 1.56 | Evaluation of the ameliorative effects of oral administration of metformin on epileptogenesis in the temporal lobe epilepsy model in rats. ( Ali, MK; Alireza, MS; Babae, JF; Hashemi, P; Nikbakht, F; Vazifehkhah, S, 2020) |
| "Metformin is an old antidiabetic drug with anti-inflammatory and neuroprotective effects." | 1.56 | The possible role of progranulin on anti-inflammatory effects of metformin in temporal lobe epilepsy. ( Khanizadeh, AM; Mojarad, TB; Nikbakht, F; Vazifehkhah, S, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Vazifehkhah, S | 2 |
| Ali, MK | 1 |
| Babae, JF | 1 |
| Hashemi, P | 1 |
| Alireza, MS | 1 |
| Nikbakht, F | 2 |
| Khanizadeh, AM | 1 |
| Mojarad, TB | 1 |
| Mehrabi, S | 1 |
| Sanadgol, N | 1 |
| Barati, M | 1 |
| Shahbazi, A | 1 |
| Vahabzadeh, G | 1 |
| Barzroudi, M | 1 |
| Seifi, M | 1 |
| Gholipourmalekabadi, M | 1 |
| Golab, F | 1 |
3 other studies available for metformin and Epilepsy, Temporal Lobe
| Article | Year |
|---|---|
Evaluation of the ameliorative effects of oral administration of metformin on epileptogenesis in the temporal lobe epilepsy model in rats.
Topics: Administration, Oral; Animals; Anticonvulsants; Cell Death; Disease Models, Animal; Electroencephalo | 2020 |
The possible role of progranulin on anti-inflammatory effects of metformin in temporal lobe epilepsy.
Topics: Animals; Anti-Inflammatory Agents; Cytokines; Disease Models, Animal; Epilepsy, Temporal Lobe; Glial | 2020 |
Evaluation of metformin effects in the chronic phase of spontaneous seizures in pilocarpine model of temporal lobe epilepsy.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Epilepsy, Temporal Lobe; Male; Metformin; Pilocarp | 2018 |