metformin has been researched along with Endomyocardial Fibrosis in 2 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Endomyocardial Fibrosis: A condition characterized by the thickening of the ventricular ENDOCARDIUM and subendocardium (MYOCARDIUM), seen mostly in children and young adults in the TROPICAL CLIMATE. The fibrous tissue extends from the apex toward and often involves the HEART VALVES causing restrictive blood flow into the respective ventricles (CARDIOMYOPATHY, RESTRICTIVE).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metformin treatment was able to reduce insulin resistance and attenuated this adverse cardiac and vascular remodeling." | 1.39 | Cardiac fibrosis and vascular remodeling are attenuated by metformin in obese rats. ( Burlá, AK; Fortes, ZB; Lobato, NS; Neves, MF; Oigman, W, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, S | 1 |
| Hong, Y | 1 |
| Jin, X | 1 |
| Zhang, G | 1 |
| Hu, Z | 1 |
| Nie, L | 1 |
| Burlá, AK | 1 |
| Lobato, NS | 1 |
| Fortes, ZB | 1 |
| Oigman, W | 1 |
| Neves, MF | 1 |
2 other studies available for metformin and Endomyocardial Fibrosis
| Article | Year |
|---|---|
A new Agkistrodon halys venom-purified protein C activator prevents myocardial fibrosis in diabetic rats.
Topics: Agkistrodon; Animals; Blood Glucose; Blotting, Western; Chromatography, Reverse-Phase; Collagen; Cro | 2015 |
Cardiac fibrosis and vascular remodeling are attenuated by metformin in obese rats.
Topics: Animals; Endomyocardial Fibrosis; Hypoglycemic Agents; Male; Metformin; Obesity; Rats; Rats, Wistar; | 2013 |