metformin has been researched along with Encephalopathy, Hepatic in 3 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the influence of metformin use on liver dysfunction and hepatic encephalopathy in a retrospective cohort of diabetic cirrhotic patients." | 7.78 | Metformin inhibits glutaminase activity and protects against hepatic encephalopathy. ( Ampuero, J; Bautista, JD; Camacho, I; del Campo, JA; Díaz-Herrero, Mdel M; Figueruela, B; Maraver, M; Nuñez, D; Ranchal, I; Rojas, Á; Romero-Gómez, M, 2012) |
| "metformin was associated with a significant inhibition of glutaminase activity levels in the small intestine of porto-caval shunted rats (0." | 5.48 | Metformin modifies glutamine metabolism in an in vitro and in vivo model of hepatic encephalopathy. ( Ampuero, J; Gallego-Durán, R; García-Valdecasas, M; Gil-GÓmez, A; Gómez-Sotelo, AI; Muñoz-Hernández, R; Ranchal, I; Rojas, Á; Romero Gómez, M, 2018) |
| "To investigate the influence of metformin use on liver dysfunction and hepatic encephalopathy in a retrospective cohort of diabetic cirrhotic patients." | 3.78 | Metformin inhibits glutaminase activity and protects against hepatic encephalopathy. ( Ampuero, J; Bautista, JD; Camacho, I; del Campo, JA; Díaz-Herrero, Mdel M; Figueruela, B; Maraver, M; Nuñez, D; Ranchal, I; Rojas, Á; Romero-Gómez, M, 2012) |
| "metformin was associated with a significant inhibition of glutaminase activity levels in the small intestine of porto-caval shunted rats (0." | 1.48 | Metformin modifies glutamine metabolism in an in vitro and in vivo model of hepatic encephalopathy. ( Ampuero, J; Gallego-Durán, R; García-Valdecasas, M; Gil-GÓmez, A; Gómez-Sotelo, AI; Muñoz-Hernández, R; Ranchal, I; Rojas, Á; Romero Gómez, M, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Mohamed, EK | 1 |
| Hafez, DM | 1 |
| Gil-GÓmez, A | 1 |
| Gómez-Sotelo, AI | 1 |
| Ranchal, I | 2 |
| Rojas, Á | 2 |
| García-Valdecasas, M | 1 |
| Muñoz-Hernández, R | 1 |
| Gallego-Durán, R | 1 |
| Ampuero, J | 2 |
| Romero Gómez, M | 1 |
| Nuñez, D | 1 |
| Díaz-Herrero, Mdel M | 1 |
| Maraver, M | 1 |
| del Campo, JA | 1 |
| Camacho, I | 1 |
| Figueruela, B | 1 |
| Bautista, JD | 1 |
| Romero-Gómez, M | 1 |
3 other studies available for metformin and Encephalopathy, Hepatic
| Article | Year |
|---|---|
Gallic acid and metformin co-administration reduce oxidative stress, apoptosis and inflammation via Fas/caspase-3 and NF-κB signaling pathways in thioacetamide-induced acute hepatic encephalopathy in rats.
Topics: Animals; Apoptosis; Caspase 3; Gallic Acid; Hepatic Encephalopathy; Inflammation; Metformin; NF-kapp | 2023 |
Metformin modifies glutamine metabolism in an in vitro and in vivo model of hepatic encephalopathy.
Topics: Ammonia; Animals; Caco-2 Cells; Child, Preschool; Glutaminase; Glutamine; Hepatic Encephalopathy; Hu | 2018 |
Metformin inhibits glutaminase activity and protects against hepatic encephalopathy.
Topics: Age Factors; Ammonia; Diabetes Complications; Enzyme Inhibitors; Female; Glutaminase; Hepatic Enceph | 2012 |