Page last updated: 2024-10-30

metformin and Duodenal Reflux

metformin has been researched along with Duodenal Reflux in 1 studies

Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.

Research Excerpts

Excerpt	Relevance	Reference
"Metformin 1 g was introduced into the stomach with a homogenized meal containing a non-absorbable marker, 14C-PEG 4000; another marker, PEG 4000, was perfused continuously into the duodenum at the ampulla of Vater."	1.27	Metformin in the digestive tract. ( Bernier, JJ; Chaussade, S; Franchisseur, C; Huchet, B; Noel, M; Vidon, N, 1988)

Research

Studies (1)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (100.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Vidon, N	1
Chaussade, S	1
Noel, M	1
Franchisseur, C	1
Huchet, B	1
Bernier, JJ	1

Clinical Trials (1)

Trial Overview

Trial			Phase	Enrollment	Study Type	Start Date	Status
Efficacy and Safety of Metformin Glycinate Compared to Metformin Hydrochloride on the Progression of Type 2 Diabetes[NCT04943692]			Phase 3	500 participants (Anticipated)	Interventional	2021-08-31	Suspended (stopped due to Administrative decision of the investigation direction)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

1 other study available for metformin and Duodenal Reflux

Article	Year
Metformin in the digestive tract. Diabetes research and clinical practice, 1988, Feb-19, Volume: 4, Issue:3 Topics: Adult; Duodenogastric Reflux; Duodenum; Gastric Emptying; Humans; Intestinal Absorption; Male; Metfo	1988