metformin has been researched along with Disorders of Sex Development in 5 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Disorders of Sex Development: In gonochoristic organisms, congenital conditions in which development of chromosomal, gonadal, or anatomical sex is atypical. Effects from exposure to abnormal levels of GONADAL HORMONES in the maternal environment, or disruption of the function of those hormones by ENDOCRINE DISRUPTORS are included.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metformin has been treated for diabetes (type 2)." | 1.51 | Metformin-induced endocrine disruption and oxidative stress of Oryzias latipes on two-generational condition. ( Kim, H; Kim, J; Kim, P; Lee, JW; Min, SA; Park, K; Shin, YJ; Yu, SD, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Niemuth, NJ | 2 |
| Klaper, RD | 2 |
| Lee, JW | 1 |
| Shin, YJ | 1 |
| Kim, H | 2 |
| Kim, J | 1 |
| Min, SA | 1 |
| Kim, P | 1 |
| Yu, SD | 1 |
| Park, K | 1 |
| Sumpter, JP | 1 |
| Scott, AP | 1 |
| Katsiadaki, I | 1 |
| Sarlis, NJ | 1 |
| Weil, SJ | 1 |
| Nelson, LM | 1 |
5 other studies available for metformin and Disorders of Sex Development
| Article | Year |
|---|---|
Low-dose metformin exposure causes changes in expression of endocrine disruption-associated genes.
Topics: Animals; Cyprinidae; Disorders of Sex Development; Endocrine Disruptors; Female; Gene Expression Reg | 2018 |
Metformin-induced endocrine disruption and oxidative stress of Oryzias latipes on two-generational condition.
Topics: Animals; Catalase; Cytochrome P450 Family 19; Disorders of Sex Development; Endocrine Disruptors; Es | 2019 |
Emerging wastewater contaminant metformin causes intersex and reduced fecundity in fish.
Topics: Animals; Cyprinidae; Disorders of Sex Development; Endocrine Disruptors; Environmental Monitoring; E | 2015 |
Comments on Niemuth, N.J. and Klaper, R.D. 2015. Emerging wastewater contaminant metformin causes intersex and reduced fecundity in fish. Chemosphere 135, 38-45.
Topics: Animals; Disorders of Sex Development; Fertility; Fishes; Metformin; Reproduction; Wastewater; Water | 2016 |
Administration of metformin to a diabetic woman with extreme hyperandrogenemia of nontumoral origin: management of infertility and prevention of inadvertent masculinization of a female fetus.
Topics: Adult; Diabetes Mellitus, Type 1; Disorders of Sex Development; Female; Humans; Hyperandrogenism; Hy | 1999 |