metformin has been researched along with Diffuse Large B-Cell Lymphoma in 4 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This study investigated the effects of statins in patients with diffuse large B-cell lymphoma (DLBCL) receiving rituximab-based chemoimmunotherapy, and the impact of commonly used drugs, metformin and aspirin, on the clinical outcomes of patients receiving chemoimmunotherapy." | 7.77 | Effect of concomitant statin, metformin, or aspirin on rituximab treatment for diffuse large B-cell lymphoma. ( Ha, T; Koo, YX; Lim, ST; Ong, WS; Quek, R; Tai, DW; Tan, DS; Tan, IB; Tao, M, 2011) |
| " This study investigated the effects of statins in patients with diffuse large B-cell lymphoma (DLBCL) receiving rituximab-based chemoimmunotherapy, and the impact of commonly used drugs, metformin and aspirin, on the clinical outcomes of patients receiving chemoimmunotherapy." | 3.77 | Effect of concomitant statin, metformin, or aspirin on rituximab treatment for diffuse large B-cell lymphoma. ( Ha, T; Koo, YX; Lim, ST; Ong, WS; Quek, R; Tai, DW; Tan, DS; Tan, IB; Tao, M, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, Y | 1 |
| Kimpara, S | 1 |
| Hoang, NM | 1 |
| Daenthanasanmak, A | 1 |
| Li, Y | 1 |
| Lu, L | 1 |
| Ngo, VN | 1 |
| Bates, PD | 1 |
| Song, L | 1 |
| Gao, X | 1 |
| Bebel, S | 1 |
| Chen, M | 1 |
| Chen, R | 1 |
| Zhang, X | 1 |
| Selberg, PE | 1 |
| Kenkre, VP | 1 |
| Waldmann, TA | 1 |
| Capitini, CM | 1 |
| Rui, L | 1 |
| Wang, Y | 1 |
| Maurer, MJ | 1 |
| Larson, MC | 1 |
| Allmer, C | 1 |
| Feldman, AL | 1 |
| Bennani, NN | 1 |
| Thompson, CA | 1 |
| Porrata, LF | 1 |
| Habermann, TM | 1 |
| Witzig, TE | 1 |
| Ansell, SM | 1 |
| Slager, SL | 1 |
| Nowakowski, GS | 1 |
| Cerhan, JR | 1 |
| Alkhatib, Y | 1 |
| Abdel Rahman, Z | 1 |
| Kuriakose, P | 1 |
| Koo, YX | 1 |
| Tan, DS | 1 |
| Tan, IB | 1 |
| Tai, DW | 1 |
| Ha, T | 1 |
| Ong, WS | 1 |
| Quek, R | 1 |
| Tao, M | 1 |
| Lim, ST | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Metformin in Combination With R-CHOP for the First Line Treatment of Patients With Diffuse Large B-cell Lymphoma[NCT03200015] | Phase 2 | 15 participants (Actual) | Interventional | 2017-10-01 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for metformin and Diffuse Large B-Cell Lymphoma
| Article | Year |
|---|---|
Impact of metformin use on the outcomes of newly diagnosed diffuse large B-cell lymphoma and follicular lymphoma.
Topics: Aged; Disease-Free Survival; Female; Humans; Lymphoma, Large B-Cell, Diffuse; Male; Metformin; Middl | 2019 |
3 other studies available for metformin and Diffuse Large B-Cell Lymphoma
| Article | Year |
|---|---|
EGR1-mediated metabolic reprogramming to oxidative phosphorylation contributes to ibrutinib resistance in B-cell lymphoma.
Topics: Adult; Agammaglobulinaemia Tyrosine Kinase; Animals; Antineoplastic Agents; Cell Line, Tumor; Drug R | 2023 |
Clinical impact of metformin in diabetic diffuse large B-cell lymphoma patients: a case-control study.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Case-Control Stu | 2017 |
Effect of concomitant statin, metformin, or aspirin on rituximab treatment for diffuse large B-cell lymphoma.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Murine-Derived; Antineoplastic C | 2011 |