metformin and Diabetic Foot
metformin has been researched along with Diabetic Foot in 8 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Diabetic Foot: Common foot problems in persons with DIABETES MELLITUS, caused by any combination of factors such as DIABETIC NEUROPATHIES; PERIPHERAL VASCULAR DISEASES; and INFECTION. With the loss of sensation and poor circulation, injuries and infections often lead to severe foot ulceration, GANGRENE and AMPUTATION.
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
"Metformin treatment reduces cell proliferation and reduces wound healing in an animal model and affects clinical outcomes in diabetic foot ulcer patients." | 7.83 | Metformin Induces Cell Cycle Arrest, Reduced Proliferation, Wound Healing Impairment In Vivo and Is Associated to Clinical Outcomes in Diabetic Foot Ulcer Patients. ( Castañeda-Delgado, JE; Cervantes-Villagrana, AR; Enciso-Moreno, JA; Fernandez-Ruiz, JC; Hernandez-Correa, AC; Nava-Ramirez, HS; Ochoa-Gonzalez, F, 2016) |
"Metformin treatment reduces cell proliferation and reduces wound healing in an animal model and affects clinical outcomes in diabetic foot ulcer patients." | 3.83 | Metformin Induces Cell Cycle Arrest, Reduced Proliferation, Wound Healing Impairment In Vivo and Is Associated to Clinical Outcomes in Diabetic Foot Ulcer Patients. ( Castañeda-Delgado, JE; Cervantes-Villagrana, AR; Enciso-Moreno, JA; Fernandez-Ruiz, JC; Hernandez-Correa, AC; Nava-Ramirez, HS; Ochoa-Gonzalez, F, 2016) |
Research
Studies (8)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (12.50) | 18.2507 |
2000's | 2 (25.00) | 29.6817 |
2010's | 3 (37.50) | 24.3611 |
2020's | 2 (25.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Mkrtumyan, AM | 1 |
Zvenigorodskaya, LA | 1 |
Shinkin, MV | 1 |
Rodríguez-Carlos, A | 1 |
Trujillo, V | 1 |
Gonzalez-Curiel, I | 1 |
Marin-Luevano, S | 1 |
Torres-Juarez, F | 1 |
Santos-Mena, A | 1 |
Rivas-Santiago, C | 1 |
Enciso-Moreno, JA | 2 |
Zaga-Clavellina, V | 1 |
Rivas-Santiago, B | 1 |
Aguiar, P | 1 |
Amaral, C | 1 |
Rodrigues, A | 1 |
de Souza, AH | 1 |
Lin, JT | 1 |
Chen, HM | 1 |
Chiu, CH | 1 |
Liang, YJ | 1 |
Ochoa-Gonzalez, F | 1 |
Cervantes-Villagrana, AR | 1 |
Fernandez-Ruiz, JC | 1 |
Nava-Ramirez, HS | 1 |
Hernandez-Correa, AC | 1 |
Castañeda-Delgado, JE | 1 |
Stiefelhagen, P | 1 |
Heikkinen, M | 1 |
Salmenperä, M | 1 |
Lepäntalo, A | 1 |
Lepäntalo, M | 1 |
Turner, RC | 1 |
Holman, RR | 1 |
Clinical Trials (1)
Trial Overview
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
The Impact of Glucose Lowering Therapies Including Dipeptidyl Peptidase-4 Inhibitor on Circulating Endothelial Progenitor Cells (EPCs) and Its Mobilising Factor Stromal Derived Factor-1α (SDF-1α) in Patients With Type 2 Diabetes[NCT02694575] | 241 participants (Actual) | Observational | 2015-03-01 | Completed | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
Reviews
3 reviews available for metformin and Diabetic Foot
Article | Year |
---|---|
AMP-activated protein kinase activators in diabetic ulcers: from animal studies to Phase II drugs under investigation.
Topics: AMP-Activated Protein Kinases; Animals; Clinical Trials, Phase II as Topic; Diabetic Foot; Drug Desi | 2014 |
Diabetes care for patients with peripheral arterial disease.
Topics: Anesthesia; Blood Pressure; Contrast Media; Diabetic Angiopathies; Diabetic Foot; Glycated Hemoglobi | 2007 |
Lessons from UK prospective diabetes study.
Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Foot; Diabeti | 1995 |
Trials
1 trial available for metformin and Diabetic Foot
Article | Year |
---|---|
Lessons from UK prospective diabetes study.
Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Foot; Diabeti | 1995 |
Other Studies
5 other studies available for metformin and Diabetic Foot
Article | Year |
---|---|
[The study of microcirculation and tissue metabolism as early diagnostic criteria for the risk of diabetic foot development].
Topics: Diabetes Mellitus; Diabetic Foot; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Laser-Doppler Fl | 2022 |
Host Defense Peptide RNase 7 Is Down-regulated in the Skin of Diabetic Patients with or without Chronic Ulcers, and its Expression is Altered with Metformin.
Topics: Adult; Chronic Disease; Diabetes Mellitus, Type 2; Diabetic Foot; Down-Regulation; Female; Humans; M | 2020 |
A diabetic foot ulcer treated with hydrogel and hyperbaric oxygen therapy: a case study.
Topics: Aged; Amputation, Surgical; Diabetes Mellitus, Type 2; Diabetic Foot; Humans; Hydrogels; Hyperbaric | 2017 |
Metformin Induces Cell Cycle Arrest, Reduced Proliferation, Wound Healing Impairment In Vivo and Is Associated to Clinical Outcomes in Diabetic Foot Ulcer Patients.
Topics: Adult; Aged; Animals; Cell Cycle Checkpoints; Cell Line; Diabetes Mellitus, Experimental; Diabetes M | 2016 |
[Nothing here follows protocol F. Elderly diabetic patients are not "DMP qualified"].
Topics: Aged; Blood Glucose; Comorbidity; Contraindications; Diabetes Mellitus, Type 2; Diabetic Foot; Diabe | 2005 |