metformin has been researched along with Dehydration in 5 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Dehydration: The condition that results from excessive loss of water from a living organism.
| Excerpt | Relevance | Reference |
|---|---|---|
| "It was reported that metformin was mainly metabolized via hepatic CYP2C11, 2D1 and 3A1/2 in rats, and in a rat model of dehydration, the expressions of hepatic CYP2C11 and 3A1/2 were not changed." | 3.74 | Effects of water deprivation on the pharmacokinetics of metformin in rats. ( Choi, YH; Lee, I; Lee, MG, 2007) |
| "The latter can provoke an acute renal failure, which may lead to a toxic accumulation of these pharmacological agents and/or increase their nephrotoxicity." | 1.46 | [Importance of stopping some medications in case of gastrointestinal disturbances leading to dehydration]. ( Krzesinski, JM; Scheen, AJ, 2017) |
| "Metformin is a first-line oral anti-hyperglycemic agent." | 1.42 | Metformin-related acidosis in a woman while performing Haj: a conservative approach. ( Althomaly, E; Alzayer, ZA; Ansari, RS; Mady, AF; Moulana, AA; Qutub, HO, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Krzesinski, JM | 1 |
| Scheen, AJ | 1 |
| Ansari, RS | 1 |
| Mady, AF | 1 |
| Qutub, HO | 1 |
| Althomaly, E | 1 |
| Alzayer, ZA | 1 |
| Moulana, AA | 1 |
| D'Elia, JA | 1 |
| Segal, AR | 1 |
| Weinrauch, LA | 1 |
| Choi, YH | 1 |
| Lee, I | 1 |
| Lee, MG | 1 |
| Ribera, L | 1 |
| González-Clemente, JM | 1 |
| López Alba, T | 1 |
| Almirall, J | 1 |
5 other studies available for metformin and Dehydration
| Article | Year |
|---|---|
[Importance of stopping some medications in case of gastrointestinal disturbances leading to dehydration].
Topics: Acute Kidney Injury; Anti-Inflammatory Agents, Non-Steroidal; Dehydration; Humans; Hypoglycemic Agen | 2017 |
Metformin-related acidosis in a woman while performing Haj: a conservative approach.
Topics: Acidosis, Lactic; Dehydration; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agents; Islam | 2015 |
Metformin-SGLT2, Dehydration, and Acidosis Potential.
Topics: Acidosis, Lactic; Aged, 80 and over; Dehydration; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Ag | 2017 |
Effects of water deprivation on the pharmacokinetics of metformin in rats.
Topics: Administration, Oral; Animals; Dehydration; Injections, Intravenous; Kidney; Male; Metabolic Clearan | 2007 |
[Fatal lactic acidosis due to metformin in a male with type 2 diabetes mellitus and dehydration. Comments about a patient information leaflet].
Topics: Acidosis, Lactic; Aged; Dehydration; Diabetes Mellitus, Type 2; Drug Labeling; Emergencies; Humans; | 2002 |