metformin has been researched along with Deficiency, Vitamin D in 9 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In both study arms, metformin reduced plasma glucose levels and improved insulin sensitivity but this effect was stronger in subjects receiving vitamin D." | 7.96 | The impact of combination therapy with metformin and exogenous vitamin D on hypothalamic-pituitary-thyroid axis activity in women with autoimmune thyroiditis and high-normal thyrotropin levels. ( Kowalcze, K; Krysiak, R; Okopień, B, 2020) |
| " In both study arms, metformin reduced plasma glucose levels and improved insulin sensitivity but this effect was stronger in subjects receiving vitamin D." | 3.96 | The impact of combination therapy with metformin and exogenous vitamin D on hypothalamic-pituitary-thyroid axis activity in women with autoimmune thyroiditis and high-normal thyrotropin levels. ( Kowalcze, K; Krysiak, R; Okopień, B, 2020) |
| "Vitamin D deficiency was recompensed in 74% of the PCOS patients who had taken calcium & vitamin D supplementation." | 2.77 | Therapeutic effects of calcium & vitamin D supplementation in women with PCOS. ( Aflatoonian, A; Firouzabadi, Rd; Modarresi, S; MohammadTaheri, S; Sekhavat, L, 2012) |
| "Metformin was found to normalize secretory function of overactive pituitary cells." | 1.62 | Vitamin D status determines the impact of metformin on circulating prolactin levels in premenopausal women. ( Kowalcze, K; Krysiak, R; Okopień, B, 2021) |
| "Vitamin D deficiency is now linked to several conditions including increased risk of CV disorders, diabetes, etc." | 1.40 | A multimodal Darwinian strategy for alleviating the atherosclerosis pandemic. ( Mathew, G; Thambi, M; Unnikrishnan, MK, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (55.56) | 24.3611 |
| 2020's | 4 (44.44) | 2.80 |
| Authors | Studies |
|---|---|
| Tracer, H | 1 |
| West, R | 1 |
| Krysiak, R | 2 |
| Kowalcze, K | 2 |
| Okopień, B | 2 |
| Aludwan, M | 1 |
| Kobyliak, N | 1 |
| Abenavoli, L | 1 |
| Kyriienko, D | 1 |
| Fagoonee, S | 1 |
| Pellicano, R | 1 |
| Komisarenko, I | 1 |
| Out, M | 1 |
| Top, WMC | 1 |
| Lehert, P | 1 |
| Schalkwijk, CA | 1 |
| Stehouwer, CDA | 1 |
| Kooy, A | 1 |
| Khan, DM | 1 |
| Jamil, A | 1 |
| Randhawa, FA | 1 |
| Butt, NF | 1 |
| Malik, U | 1 |
| Mathew, G | 1 |
| Thambi, M | 1 |
| Unnikrishnan, MK | 1 |
| Krul-Poel, YH | 1 |
| Agca, R | 1 |
| Lips, P | 1 |
| van Wijland, H | 1 |
| Stam, F | 1 |
| Simsek, S | 1 |
| Firouzabadi, Rd | 1 |
| Aflatoonian, A | 1 |
| Modarresi, S | 1 |
| Sekhavat, L | 1 |
| MohammadTaheri, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Study of Metformin HCL in Patients With Type 2 Diabetes Intensively Treated With Insulin: a Treatment Strategy for Insulin Resistance in Type 2 Diabetes Mellitus: a Randomized Controlled Trial[NCT00375388] | Phase 3 | 400 participants | Interventional | 1998-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 trials available for metformin and Deficiency, Vitamin D
| Article | Year |
|---|---|
Long-term treatment with metformin in type 2 diabetes and vitamin D levels: A post-hoc analysis of a randomized placebo-controlled trial.
Topics: 25-Hydroxyvitamin D 2; Age Factors; Aged; Body Mass Index; Calcifediol; Diabetes Mellitus, Type 2; D | 2018 |
Efficacy of oral vitamin D on glycated haemoglobin (HbA1c) in type 2 diabetics having vitamin D deficiency - A randomized controlled trial.
Topics: Administration, Oral; Adult; Aged; Diabetes Mellitus, Type 2; Dietary Supplements; Female; Glycated | 2018 |
Vitamin D status is associated with skin autofluorescence in patients with type 2 diabetes mellitus: a preliminary report.
Topics: Aged; Cross-Sectional Studies; Diabetes Complications; Diabetes Mellitus, Type 2; Drug Therapy, Comb | 2015 |
Therapeutic effects of calcium & vitamin D supplementation in women with PCOS.
Topics: Adult; Calcium; Case-Control Studies; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; | 2012 |
5 other studies available for metformin and Deficiency, Vitamin D
| Article | Year |
|---|---|
Screening for Vitamin D Deficiency in Adults.
Topics: Antihypertensive Agents; Asymptomatic Diseases; Body Mass Index; Diabetes Mellitus, Type 2; Humans; | 2021 |
The impact of combination therapy with metformin and exogenous vitamin D on hypothalamic-pituitary-thyroid axis activity in women with autoimmune thyroiditis and high-normal thyrotropin levels.
Topics: Adult; Blood Glucose; Case-Control Studies; Drug Synergism; Drug Therapy, Combination; Female; Hashi | 2020 |
Vitamin D3 deficiency is associated with more severe insulin resistance and metformin use in patients with type 2 diabetes.
Topics: Adolescent; Adult; Aged; Body Mass Index; C-Peptide; Cholecalciferol; Cross-Sectional Studies; Diabe | 2020 |
Vitamin D status determines the impact of metformin on circulating prolactin levels in premenopausal women.
Topics: Adult; Blood Glucose; Body Mass Index; Comorbidity; Female; Gonadal Steroid Hormones; Humans; Hyperp | 2021 |
A multimodal Darwinian strategy for alleviating the atherosclerosis pandemic.
Topics: AMP-Activated Protein Kinases; Animals; Atherosclerosis; Biological Evolution; Humans; Hygiene; Inte | 2014 |