Page last updated: 2024-10-30

metformin and Deficiency, Thiamine

metformin has been researched along with Deficiency, Thiamine in 3 studies

Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.

Research Excerpts

ExcerptRelevanceReference
" We herein report a case of cardiac dysfunction due to thiamine deficiency after hemodialysis in a patient with suspected biguanide-related lactic acidosis."8.12Cardiac Dysfunction Due to Thiamine Deficiency after Hemodialysis for Biguanide-related Lactic Acidosis. ( Jimura, F; Kachi, N; Tamaki, H; Tsushima, H, 2022)
" The significance of this topic has been illustrated by the recently established competition between thiamine and the antidiabetic drug metformin for common transporters, which can be the reason for the thiamine deficiency underlying metformin side effects."5.01Mechanisms of Non-coenzyme Action of Thiamine: Protein Targets and Medical Significance. ( Aleshin, VA; Bunik, VI; Mkrtchyan, GV, 2019)
" We herein report a case of cardiac dysfunction due to thiamine deficiency after hemodialysis in a patient with suspected biguanide-related lactic acidosis."4.12Cardiac Dysfunction Due to Thiamine Deficiency after Hemodialysis for Biguanide-related Lactic Acidosis. ( Jimura, F; Kachi, N; Tamaki, H; Tsushima, H, 2022)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Tamaki, H1
Tsushima, H1
Kachi, N1
Jimura, F1
Aleshin, VA1
Mkrtchyan, GV1
Bunik, VI1
Alston, TA1

Reviews

1 review available for metformin and Deficiency, Thiamine

ArticleYear
Mechanisms of Non-coenzyme Action of Thiamine: Protein Targets and Medical Significance.
    Biochemistry. Biokhimiia, 2019, Volume: 84, Issue:8

    Topics: Animals; Brain; Coenzymes; Humans; Hypoglycemic Agents; Metformin; Mice; Phosphorylation; Protein Tr

2019

Other Studies

2 other studies available for metformin and Deficiency, Thiamine

ArticleYear
Cardiac Dysfunction Due to Thiamine Deficiency after Hemodialysis for Biguanide-related Lactic Acidosis.
    Internal medicine (Tokyo, Japan), 2022, Oct-01, Volume: 61, Issue:19

    Topics: Acidosis, Lactic; Beriberi; Biguanides; Diabetes Mellitus, Type 2; Heart Diseases; Humans; Hypoglyce

2022
Does metformin interfere with thiamine?
    Archives of internal medicine, 2003, Apr-28, Volume: 163, Issue:8

    Topics: Drug Interactions; Humans; Hypoglycemic Agents; Metformin; Thiamine; Thiamine Deficiency; Vitamin B

2003