Page last updated: 2024-10-30

metformin and Deep Vein Thrombosis

metformin has been researched along with Deep Vein Thrombosis in 4 studies

Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.

Research Excerpts

ExcerptRelevanceReference
"Metformin is hypothesized to protect against the risk of venous thromboembolism (VTE); however, there is a paucity of data supporting this hypothesis."8.12Association of Metformin Use With Risk of Venous Thromboembolism in Adults With Type 2 Diabetes: A General-Population-Based Cohort Study. ( Lei, G; Li, C; Li, X; Sha, T; Wei, J; Wu, J; Yang, Z; Zeng, C; Zhang, Y, 2022)
"Vitamin B12 deficiency may be induced by long-term use of metformin, which may in turn lead to hyperhomocysteinemia."7.74Hyperhomocysteinemia, deep vein thrombosis and vitamin B12 deficiency in a metformin-treated diabetic patient. ( Chang, CS; Chung, CY; Lin, HY; Lin, JS; Shen, MC; Wang, ML, 2007)
"The effects of metformin on venous thrombosis in patient with type 2 DM have not been reported."5.40Metformin use in patients with type 2 diabetes mellitus is associated with reduced risk of deep vein thrombosis: a non-randomized, pair-matched cohort study. ( Chan, WL; Chen, JW; Chung, CM; Huang, CC; Huang, PH; Leu, HB; Lin, SJ; Lu, DY, 2014)
"Metformin is hypothesized to protect against the risk of venous thromboembolism (VTE); however, there is a paucity of data supporting this hypothesis."4.12Association of Metformin Use With Risk of Venous Thromboembolism in Adults With Type 2 Diabetes: A General-Population-Based Cohort Study. ( Lei, G; Li, C; Li, X; Sha, T; Wei, J; Wu, J; Yang, Z; Zeng, C; Zhang, Y, 2022)
"Vitamin B12 deficiency may be induced by long-term use of metformin, which may in turn lead to hyperhomocysteinemia."3.74Hyperhomocysteinemia, deep vein thrombosis and vitamin B12 deficiency in a metformin-treated diabetic patient. ( Chang, CS; Chung, CY; Lin, HY; Lin, JS; Shen, MC; Wang, ML, 2007)
"The effects of metformin on venous thrombosis in patient with type 2 DM have not been reported."1.40Metformin use in patients with type 2 diabetes mellitus is associated with reduced risk of deep vein thrombosis: a non-randomized, pair-matched cohort study. ( Chan, WL; Chen, JW; Chung, CM; Huang, CC; Huang, PH; Leu, HB; Lin, SJ; Lu, DY, 2014)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's1 (25.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Sha, T1
Zhang, Y1
Li, C1
Lei, G1
Wu, J1
Li, X1
Yang, Z1
Zeng, C1
Wei, J1
Lu, DY1
Huang, CC1
Huang, PH1
Chung, CM1
Lin, SJ1
Chen, JW1
Chan, WL1
Leu, HB1
Musarrat, K1
Kalathil, D1
Varughese, GI1
Lin, HY1
Chung, CY1
Chang, CS1
Wang, ML1
Lin, JS1
Shen, MC1

Other Studies

4 other studies available for metformin and Deep Vein Thrombosis

ArticleYear
Association of Metformin Use With Risk of Venous Thromboembolism in Adults With Type 2 Diabetes: A General-Population-Based Cohort Study.
    American journal of epidemiology, 2022, 03-24, Volume: 191, Issue:5

    Topics: Adult; Cohort Studies; Diabetes Mellitus, Type 2; Humans; Incidence; Metformin; Pulmonary Embolism;

2022
Metformin use in patients with type 2 diabetes mellitus is associated with reduced risk of deep vein thrombosis: a non-randomized, pair-matched cohort study.
    BMC cardiovascular disorders, 2014, Dec-15, Volume: 14

    Topics: Aged; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agents; Kaplan-Meier Estimate; Male; M

2014
Metformin, B12 and homocysteine levels: the plausible cause or effect?
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2008, Volume: 107, Issue:6

    Topics: Homocysteine; Humans; Hyperhomocysteinemia; Metformin; Venous Thrombosis; Vitamin B 12; Vitamin B 12

2008
Hyperhomocysteinemia, deep vein thrombosis and vitamin B12 deficiency in a metformin-treated diabetic patient.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2007, Volume: 106, Issue:9

    Topics: Aged; Diabetes Mellitus, Type 2; Female; Humans; Hyperhomocysteinemia; Hypoglycemic Agents; Metformi

2007