metformin has been researched along with Cystic Fibrosis in 2 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 2 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Forrest, OA | 1 |
Ingersoll, SA | 1 |
Preininger, MK | 1 |
Laval, J | 1 |
Limoli, DH | 1 |
Brown, MR | 1 |
Lee, FE | 1 |
Bedi, B | 1 |
Sadikot, RT | 1 |
Goldberg, JB | 1 |
Tangpricha, V | 1 |
Gaggar, A | 1 |
Tirouvanziam, R | 1 |
Myerburg, MM | 1 |
King, JD | 1 |
Oyster, NM | 1 |
Fitch, AC | 1 |
Magill, A | 1 |
Baty, CJ | 1 |
Watkins, SC | 1 |
Kolls, JK | 1 |
Pilewski, JM | 1 |
Hallows, KR | 1 |
2 other studies available for metformin and Cystic Fibrosis
Article | Year |
---|---|
Frontline Science: Pathological conditioning of human neutrophils recruited to the airway milieu in cystic fibrosis.
Topics: Animals; Azabicyclo Compounds; Benzoates; Blood Cells; Bone Marrow Cells; Cells, Cultured; Chemotaxi | 2018 |
AMPK agonists ameliorate sodium and fluid transport and inflammation in cystic fibrosis airway epithelial cells.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Anti-Inflammatory Agents; Cell Polarity; | 2010 |