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metformin and Cystic Fibrosis

metformin has been researched along with Cystic Fibrosis in 2 studies

Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.

Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Forrest, OA1
Ingersoll, SA1
Preininger, MK1
Laval, J1
Limoli, DH1
Brown, MR1
Lee, FE1
Bedi, B1
Sadikot, RT1
Goldberg, JB1
Tangpricha, V1
Gaggar, A1
Tirouvanziam, R1
Myerburg, MM1
King, JD1
Oyster, NM1
Fitch, AC1
Magill, A1
Baty, CJ1
Watkins, SC1
Kolls, JK1
Pilewski, JM1
Hallows, KR1

Other Studies

2 other studies available for metformin and Cystic Fibrosis

ArticleYear
Frontline Science: Pathological conditioning of human neutrophils recruited to the airway milieu in cystic fibrosis.
    Journal of leukocyte biology, 2018, Volume: 104, Issue:4

    Topics: Animals; Azabicyclo Compounds; Benzoates; Blood Cells; Bone Marrow Cells; Cells, Cultured; Chemotaxi

2018
AMPK agonists ameliorate sodium and fluid transport and inflammation in cystic fibrosis airway epithelial cells.
    American journal of respiratory cell and molecular biology, 2010, Volume: 42, Issue:6

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Anti-Inflammatory Agents; Cell Polarity;

2010