metformin has been researched along with Critical Illness in 8 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Critical Illness: A disease or state in which death is possible or imminent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Whether metformin exposure is associated with improved outcomes in patients with type 2 diabetes mellitus and sepsis." | 8.12 | Association of Metformin Use During Hospitalization and Mortality in Critically Ill Adults With Type 2 Diabetes Mellitus and Sepsis. ( Angus, DC; Chang, CH; Del Rio-Pertuz, G; Gómez, H; Kellum, JA; Liu, Q; Manrique-Caballero, CL; Murugan, R; Priyanka, P; Wang, S; Zuckerbraun, BS, 2022) |
| "From January 2004 to November 2008, 11 cases of metformin-associated lactic acidosis were seen at a medical center in Taiwan." | 7.75 | Impact of acute kidney injury on metformin-associated lactic acidosis. ( Wen, YK, 2009) |
| "A 74-year-old man with cardiac failure and renal impairment was admitted to the cardiothoracic intensive care unit with metformin-induced lactic acidosis and shock." | 7.75 | Continuous venovenous haemodiafiltration for metformin-induced lactic acidosis. ( MacLaren, G; Pan, LT, 2009) |
| " Metformin and SGLT2 inhibitors should be discontinued in patients with severe forms of COVID-19 owing to the risks of lactic acidosis and ketoacidosis." | 5.05 | COVID-19 in diabetic patients: Related risks and specifics of management. ( Hermans, MP; Maiter, D; Orioli, L; Thissen, JP; Vandeleene, B; Yombi, JC, 2020) |
| "Whether metformin exposure is associated with improved outcomes in patients with type 2 diabetes mellitus and sepsis." | 4.12 | Association of Metformin Use During Hospitalization and Mortality in Critically Ill Adults With Type 2 Diabetes Mellitus and Sepsis. ( Angus, DC; Chang, CH; Del Rio-Pertuz, G; Gómez, H; Kellum, JA; Liu, Q; Manrique-Caballero, CL; Murugan, R; Priyanka, P; Wang, S; Zuckerbraun, BS, 2022) |
| "Neither diabetes mellitus nor preadmission insulin or metformin use are associated with altered disease presentation, outcome or host response in patients with sepsis requiring intensive care." | 3.83 | Association of diabetes and diabetes treatment with the host response in critically ill sepsis patients. ( Bonten, MM; Cremer, OL; Hoogendijk, AJ; Horn, J; Klein Klouwenberg, PM; Nürnberg, P; Schultz, MJ; Scicluna, BP; van der Poll, T; van Vught, LA; Wiewel, MA, 2016) |
| "From January 2004 to November 2008, 11 cases of metformin-associated lactic acidosis were seen at a medical center in Taiwan." | 3.75 | Impact of acute kidney injury on metformin-associated lactic acidosis. ( Wen, YK, 2009) |
| "A 74-year-old man with cardiac failure and renal impairment was admitted to the cardiothoracic intensive care unit with metformin-induced lactic acidosis and shock." | 3.75 | Continuous venovenous haemodiafiltration for metformin-induced lactic acidosis. ( MacLaren, G; Pan, LT, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 3 (37.50) | 2.80 |
| Authors | Studies |
|---|---|
| Gómez, H | 1 |
| Del Rio-Pertuz, G | 1 |
| Priyanka, P | 1 |
| Manrique-Caballero, CL | 1 |
| Chang, CH | 1 |
| Wang, S | 1 |
| Liu, Q | 1 |
| Zuckerbraun, BS | 1 |
| Murugan, R | 1 |
| Angus, DC | 1 |
| Kellum, JA | 1 |
| Orioli, L | 1 |
| Hermans, MP | 1 |
| Thissen, JP | 1 |
| Maiter, D | 1 |
| Vandeleene, B | 1 |
| Yombi, JC | 1 |
| Posma, RA | 1 |
| Hulman, A | 1 |
| Thomsen, RW | 1 |
| Jespersen, B | 1 |
| Nijsten, MW | 1 |
| Christiansen, CF | 1 |
| van Vught, LA | 1 |
| Scicluna, BP | 1 |
| Hoogendijk, AJ | 1 |
| Wiewel, MA | 1 |
| Klein Klouwenberg, PM | 1 |
| Cremer, OL | 1 |
| Horn, J | 1 |
| Nürnberg, P | 1 |
| Bonten, MM | 1 |
| Schultz, MJ | 1 |
| van der Poll, T | 1 |
| Wen, YK | 1 |
| Pan, LT | 1 |
| MacLaren, G | 1 |
| Mojtahedzadeh, M | 1 |
| Jafarieh, A | 1 |
| Najafi, A | 1 |
| Khajavi, MR | 1 |
| Khalili, N | 1 |
| Read, JA | 1 |
| Bearfield, P | 1 |
| Agarwal, B | 1 |
1 review available for metformin and Critical Illness
| Article | Year |
|---|---|
COVID-19 in diabetic patients: Related risks and specifics of management.
Topics: Acidosis, Lactic; Betacoronavirus; Comorbidity; Coronavirus Infections; COVID-19; Critical Illness; | 2020 |
1 trial available for metformin and Critical Illness
| Article | Year |
|---|---|
Comparison of metformin and insulin in the control of hyperglycaemia in non-diabetic critically ill patients.
Topics: Adult; APACHE; Blood Glucose; Critical Care; Critical Illness; Double-Blind Method; Female; Humans; | 2012 |
6 other studies available for metformin and Critical Illness
| Article | Year |
|---|---|
Association of Metformin Use During Hospitalization and Mortality in Critically Ill Adults With Type 2 Diabetes Mellitus and Sepsis.
Topics: Adult; Critical Illness; Diabetes Mellitus, Type 2; Hospitalization; Humans; Metformin; Retrospectiv | 2022 |
Metformin use and early lactate levels in critically ill patients according to chronic and acute renal impairment.
Topics: Aged; Critical Illness; Denmark; Female; Humans; Hypoglycemic Agents; Lactic Acid; Male; Metformin; | 2020 |
Association of diabetes and diabetes treatment with the host response in critically ill sepsis patients.
Topics: Aged; Biomarkers; Chemokine CX3CL1; Critical Illness; Diabetes Mellitus; E-Selectin; Female; Humans; | 2016 |
Impact of acute kidney injury on metformin-associated lactic acidosis.
Topics: Academic Medical Centers; Acidosis, Lactic; Acute Kidney Injury; Aged; Anti-Bacterial Agents; Bicarb | 2009 |
Continuous venovenous haemodiafiltration for metformin-induced lactic acidosis.
Topics: Acidosis, Lactic; Aged; Critical Illness; Hemofiltration; Humans; Hypoglycemic Agents; Intensive Car | 2009 |
Glycaemic control in critically ill patients with myotonic dystrophy.
Topics: Critical Illness; Humans; Hyperglycemia; Hypoglycemic Agents; Male; Metformin; Myotonic Dystrophy | 2008 |