metformin has been researched along with Compartment Syndromes in 2 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Compartment Syndromes: Conditions in which increased pressure within a limited space compromises the BLOOD CIRCULATION and function of tissue within that space. Some of the causes of increased pressure are TRAUMA, tight dressings, HEMORRHAGE, and exercise. Sequelae include nerve compression (NERVE COMPRESSION SYNDROMES); PARALYSIS; and ISCHEMIC CONTRACTURE. FASCIOTOMY is often used to decompress increased pressure and eliminate pain associated with compartment syndromes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report the case of a 46-yr-old male who developed severe lactic acidosis, cardiorespiratory arrest, and rhabdomyolysis following an overdose of metformin and ramipril." | 7.74 | Severe lactic acidosis and rhabdomyolysis following metformin and ramipril overdose. ( Bramham, K; Galea, M; Jelacin, N; White, I, 2007) |
| "Capillary leak syndrome is a condition that increases systemic capillary permeability and causes characteristic manifestations such as recurrent hypovolemia, systemic edema, and hemoconcentration." | 5.56 | Multiple limb compartment syndrome as a manifestation of capillary leak syndrome secondary to metformin and dipeptidyl peptidase IV inhibitor overdose: A case report. ( Hirakawa, A; Jingushi, N; Kasugai, D; Tajima, K; Uenishi, N, 2020) |
| "We report the case of a 46-yr-old male who developed severe lactic acidosis, cardiorespiratory arrest, and rhabdomyolysis following an overdose of metformin and ramipril." | 3.74 | Severe lactic acidosis and rhabdomyolysis following metformin and ramipril overdose. ( Bramham, K; Galea, M; Jelacin, N; White, I, 2007) |
| "Capillary leak syndrome is a condition that increases systemic capillary permeability and causes characteristic manifestations such as recurrent hypovolemia, systemic edema, and hemoconcentration." | 1.56 | Multiple limb compartment syndrome as a manifestation of capillary leak syndrome secondary to metformin and dipeptidyl peptidase IV inhibitor overdose: A case report. ( Hirakawa, A; Jingushi, N; Kasugai, D; Tajima, K; Uenishi, N, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kasugai, D | 1 |
| Tajima, K | 1 |
| Jingushi, N | 1 |
| Uenishi, N | 1 |
| Hirakawa, A | 1 |
| Galea, M | 1 |
| Jelacin, N | 1 |
| Bramham, K | 1 |
| White, I | 1 |
2 other studies available for metformin and Compartment Syndromes
| Article | Year |
|---|---|
Multiple limb compartment syndrome as a manifestation of capillary leak syndrome secondary to metformin and dipeptidyl peptidase IV inhibitor overdose: A case report.
Topics: Adolescent; Capillary Leak Syndrome; Compartment Syndromes; Decompression, Surgical; Dipeptidyl-Pept | 2020 |
Severe lactic acidosis and rhabdomyolysis following metformin and ramipril overdose.
Topics: Acidosis, Lactic; Antihypertensive Agents; Compartment Syndromes; Drug Overdose; Hemofiltration; Hum | 2007 |