metformin has been researched along with Colitis Gravis in 8 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
| Excerpt | Relevance | Reference |
|---|---|---|
| "It is revealed that metformin alleviated inflammation and underlying mechanism may result from inhibition of SPHK1/S1P signaling pathway." | 8.02 | Metformin alleviates inflammation in oxazolone induced ulcerative colitis in rats: plausible role of sphingosine kinase 1/sphingosine 1 phosphate signaling pathway. ( Abu-Risha, SE; El-Kadem, AH; El-Mahdy, NA; El-Sayad, ME, 2021) |
| "It is revealed that metformin alleviated inflammation and underlying mechanism may result from inhibition of SPHK1/S1P signaling pathway." | 4.02 | Metformin alleviates inflammation in oxazolone induced ulcerative colitis in rats: plausible role of sphingosine kinase 1/sphingosine 1 phosphate signaling pathway. ( Abu-Risha, SE; El-Kadem, AH; El-Mahdy, NA; El-Sayad, ME, 2021) |
| "Metformin has pleiotropic effects including anti-inflammatory properties and effects on the gut microbiome." | 1.72 | Metformin use is not associated with reduced risk of older onset inflammatory bowel disease: a Danish nationwide population-based study. ( Allin, KH; Jacobsen, RK; Jensen, CB; Jess, T, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 5 (62.50) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, J | 1 |
| Chen, C | 1 |
| Ren, Y | 1 |
| Zhou, X | 1 |
| Yu, S | 1 |
| Shaaban, AA | 1 |
| Abdelhamid, AM | 1 |
| Shaker, ME | 1 |
| Cavalu, S | 1 |
| Maghiar, AM | 1 |
| Alsayegh, AA | 1 |
| Babalghith, AO | 1 |
| El-Ahwany, E | 1 |
| Amin, NA | 1 |
| Mohammed, OA | 1 |
| Eissa, H | 1 |
| Gaafar, AGA | 1 |
| Batiha, GE | 1 |
| Saber, S | 1 |
| Allin, KH | 1 |
| Jensen, CB | 1 |
| Jacobsen, RK | 1 |
| Jess, T | 1 |
| Wanchaitanawong, W | 1 |
| Thinrungroj, N | 1 |
| Chattipakorn, SC | 1 |
| Chattipakorn, N | 1 |
| Shinlapawittayatorn, K | 1 |
| El-Mahdy, NA | 1 |
| El-Sayad, ME | 1 |
| El-Kadem, AH | 1 |
| Abu-Risha, SE | 1 |
| Pandey, A | 1 |
| Verma, S | 1 |
| Kumar, VL | 1 |
| Di Fusco, D | 1 |
| Dinallo, V | 1 |
| Monteleone, I | 1 |
| Laudisi, F | 1 |
| Marafini, I | 1 |
| Franzè, E | 1 |
| Di Grazia, A | 1 |
| Dwairi, R | 1 |
| Colantoni, A | 1 |
| Ortenzi, A | 1 |
| Stolfi, C | 1 |
| Monteleone, G | 1 |
| Brouwers, MC | 1 |
| Schaper, N | 1 |
| Keeris, L | 1 |
1 review available for metformin and Colitis Gravis
| Article | Year |
|---|---|
Repurposing metformin as a potential treatment for inflammatory bowel disease: Evidence from cell to the clinic.
Topics: Anti-Inflammatory Agents; Biological Factors; Colitis, Ulcerative; Drug Repositioning; Humans; Infla | 2022 |
7 other studies available for metformin and Colitis Gravis
| Article | Year |
|---|---|
Metformin alleviates intestinal epithelial barrier damage by inhibiting endoplasmic reticulum stress-induced cell apoptosis in colitis cell model.
Topics: Apoptosis; Caco-2 Cells; Colitis, Ulcerative; Endoplasmic Reticulum Stress; Humans; Metformin | 2021 |
Combining the HSP90 inhibitor TAS-116 with metformin effectively degrades the NLRP3 and attenuates inflammasome activation in rats: A new management paradigm for ulcerative colitis.
Topics: Animals; Benzamides; Colitis, Ulcerative; Dextran Sulfate; Inflammasomes; Inflammation; Metformin; M | 2022 |
Metformin use is not associated with reduced risk of older onset inflammatory bowel disease: a Danish nationwide population-based study.
Topics: Aged; Anti-Inflammatory Agents; Case-Control Studies; Colitis, Ulcerative; Denmark; Dipeptidyl-Pepti | 2022 |
Metformin alleviates inflammation in oxazolone induced ulcerative colitis in rats: plausible role of sphingosine kinase 1/sphingosine 1 phosphate signaling pathway.
Topics: Animals; Colitis, Ulcerative; Colon; Inflammation; Lysophospholipids; Male; Metformin; Oxazolone; Ph | 2021 |
Metformin maintains mucosal integrity in experimental model of colitis by inhibiting oxidative stress and pro-inflammatory signaling.
Topics: Animals; Anti-Inflammatory Agents; Biomarkers; Colitis, Ulcerative; Colon; Cyclooxygenase 2; Disease | 2017 |
Metformin inhibits inflammatory signals in the gut by controlling AMPK and p38 MAP kinase activation.
Topics: AMP-Activated Protein Kinases; Animals; Colitis, Ulcerative; Colon; Disease Models, Animal; Drug Eva | 2018 |
Does glucose infusion exacerbate metformin-associated lactate acidosis? A case report.
Topics: Acidosis, Lactic; Acute Kidney Injury; Colectomy; Colitis, Ulcerative; Diabetes Mellitus, Type 2; Fe | 2009 |