metformin has been researched along with Cochlear Hearing Loss in 4 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 40-year-old man with sensorineural hearing loss and diabetes mellitus was hospitalized with acute-onset impaired consciousness and clumsiness in his left hand." | 5.91 | Mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes diagnosed after metformin-triggered stroke-like episodes. ( Ishiguchi, H; Ito, H; Murakami, K; Sakamoto, K, 2023) |
| "A 40-year-old man with sensorineural hearing loss and diabetes mellitus was hospitalized with acute-onset impaired consciousness and clumsiness in his left hand." | 1.91 | Mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes diagnosed after metformin-triggered stroke-like episodes. ( Ishiguchi, H; Ito, H; Murakami, K; Sakamoto, K, 2023) |
| "Hearing impairments are the most common symptom of congenital defects, and they generally remain intractable to treatment." | 1.46 | Cochlear Cell Modeling Using Disease-Specific iPSCs Unveils a Degenerative Phenotype and Suggests Treatments for Congenital Progressive Hearing Loss. ( Akamatsu, W; Fujioka, M; Hosoya, M; Matsunaga, T; Ogawa, K; Okamoto, S; Okano, H; Sone, T; Ueda, HR; Ukai, H, 2017) |
| "Metformin was not cytotoxic or radioprotective in cultured auditory hair cells." | 1.40 | Safety and otoprotection of metformin in radiation-induced sensorineural hearing loss in the guinea pig. ( Daniel, SJ; Devic, S; Mujica-Mota, MA; Salehi, P, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Murakami, K | 1 |
| Sakamoto, K | 1 |
| Ishiguchi, H | 1 |
| Ito, H | 1 |
| Mujica-Mota, MA | 1 |
| Salehi, P | 1 |
| Devic, S | 1 |
| Daniel, SJ | 1 |
| Hosoya, M | 1 |
| Fujioka, M | 1 |
| Sone, T | 1 |
| Okamoto, S | 1 |
| Akamatsu, W | 1 |
| Ukai, H | 1 |
| Ueda, HR | 1 |
| Ogawa, K | 1 |
| Matsunaga, T | 1 |
| Okano, H | 1 |
| Miller, DK | 1 |
| Brinson, AJ | 1 |
| Catalano, G | 1 |
| Catalano, MC | 1 |
4 other studies available for metformin and Cochlear Hearing Loss
| Article | Year |
|---|---|
Mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes diagnosed after metformin-triggered stroke-like episodes.
Topics: Acidosis, Lactic; Adult; Hearing Loss, Sensorineural; Humans; Male; MELAS Syndrome; Metformin; Strok | 2023 |
Safety and otoprotection of metformin in radiation-induced sensorineural hearing loss in the guinea pig.
Topics: Animals; Disease Models, Animal; Evoked Potentials, Auditory, Brain Stem; Guinea Pigs; Hair Cells, A | 2014 |
Cochlear Cell Modeling Using Disease-Specific iPSCs Unveils a Degenerative Phenotype and Suggests Treatments for Congenital Progressive Hearing Loss.
Topics: Adolescent; Adult; Cell Line; Child; Child, Preschool; Cochlea; Female; Goiter, Nodular; Hearing Los | 2017 |
Lactic acidosis, hypotension, and sensorineural hearing loss following intentional metformin overdose.
Topics: Acidosis, Lactic; Drug Overdose; Glyburide; Hearing Loss, Sensorineural; Humans; Hypoglycemia; Hypog | 2011 |