metformin has been researched along with Clostridioides difficile Infection in 3 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Here metformin hydrochloride was suggested to be useful for the treatment of recurrent CDI with type 2 diabetes mellitus." | 1.91 | [A case of recurrent Clostridium difficile infection with type 2 diabetes mellitus indicating the usefulness of metformin hydrochloride]. ( Obata, K; Yamashita, S, 2023) |
| "Data on risk factors for Clostridium difficile infection (CDI) in diabetic patients are scarce." | 1.42 | Predicting Clostridium difficile infection in diabetic patients and the effect of metformin therapy: a retrospective, case-control study. ( Barsheshet, A; Bishara, J; Eliakim-Raz, N; Fishman, G; Goldberg, E; Stein, GY; Yahav, D; Zvi, HB, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Obata, K | 1 |
| Yamashita, S | 1 |
| Staley, C | 1 |
| Kaiser, T | 1 |
| Vaughn, BP | 1 |
| Graiziger, C | 1 |
| Hamilton, MJ | 1 |
| Kabage, AJ | 1 |
| Khoruts, A | 1 |
| Sadowsky, MJ | 1 |
| Eliakim-Raz, N | 1 |
| Fishman, G | 1 |
| Yahav, D | 1 |
| Goldberg, E | 1 |
| Stein, GY | 1 |
| Zvi, HB | 1 |
| Barsheshet, A | 1 |
| Bishara, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Aiming to Reduce Disease-related Gastrointestinal Symptoms in Systemic Sclerosis by Repeat Intestinal Infusions of Anaerobic Cultivated Human Intestinal Microbiome (ACHIM); a Randomized, Double-blind Placebo-controlled 20 Week Study[NCT04300426] | Phase 2 | 75 participants (Actual) | Interventional | 2020-09-24 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 other studies available for metformin and Clostridioides difficile Infection
| Article | Year |
|---|---|
[A case of recurrent Clostridium difficile infection with type 2 diabetes mellitus indicating the usefulness of metformin hydrochloride].
Topics: Aged; Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Diabetes Mellitus, Ty | 2023 |
Durable Long-Term Bacterial Engraftment following Encapsulated Fecal Microbiota Transplantation To Treat Clostridium difficile Infection.
Topics: Adult; Aged; Bacteroidetes; Bayes Theorem; Clostridioides difficile; Clostridium Infections; Cohort | 2019 |
Predicting Clostridium difficile infection in diabetic patients and the effect of metformin therapy: a retrospective, case-control study.
Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Clostridioides difficile; Clostridium Infectio | 2015 |