Page last updated: 2024-10-30

metformin and Cirrhoses, Experimental Liver

metformin has been researched along with Cirrhoses, Experimental Liver in 5 studies

Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.

Research Excerpts

ExcerptRelevanceReference
"Insulin sensitivity was determined by euglycemic hyperinsulinemic clamp."1.48Salvianolate Reduces Glucose Metabolism Disorders in Dimethylnitrosamine-Induced Cirrhotic Rats. ( Liu, CH; Tang, LR; Tao, YY; Wang, HN, 2018)
"Metformin treatment remarkably improved liver function, alleviated lipid peroxidation and histological damages of the liver, and ameliorated glucose intolerance and insulin resistance."1.43Metformin improves hepatic IRS2/PI3K/Akt signaling in insulin-resistant rats of NASH and cirrhosis. ( Chen, F; Liu, Y; Ping, J; Ruo, R; Shou, Q; Xu, H; Zhou, Y, 2016)
"The animal model of type 2 diabetes with hepatic fibrosis was successfully made."1.36[Effect of metformin on the formation of hepatic fibrosis in type 2 diabetic rats]. ( Chen, BN; Du, GH; Qiang, GF; Shi, LL; Xuan, Q; Yang, XY; Zhang, HA; Zhang, L, 2010)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (60.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
Moheimani, HR1
Amiriani, T1
Alizadeh, AM1
Jand, Y1
Shakiba, D1
Ensan, PS1
Jafarzadeh, F1
Rajaei, M1
Enayati, A1
Pourabouk, M1
Aliazadeh, S1
Pourkhani, AH1
Mazaheri, Z1
Zeyghami, MA1
Dehpour, A1
Khori, V1
Sato, Y2
Qiu, J1
Hirose, T1
Miura, T1
Kohzuki, M1
Ito, O1
Tang, LR1
Tao, YY1
Liu, CH1
Wang, HN1
Xu, H1
Zhou, Y1
Liu, Y1
Ping, J1
Shou, Q1
Chen, F1
Ruo, R1
Qiang, GF1
Zhang, L1
Xuan, Q1
Yang, XY1
Shi, LL1
Zhang, HA1
Chen, BN1
Du, GH1

Other Studies

5 other studies available for metformin and Cirrhoses, Experimental Liver

ArticleYear
Preconditioning and anti-apoptotic effects of Metformin and Cyclosporine-A in an isolated bile duct-ligated rat heart.
    European journal of pharmacology, 2021, Feb-15, Volume: 893

    Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Apoptosis Regulatory Proteins; Bile Ducts; Cardio

2021
Metformin slows liver cyst formation and fibrosis in experimental model of polycystic liver disease.
    American journal of physiology. Gastrointestinal and liver physiology, 2021, 04-01, Volume: 320, Issue:4

    Topics: AMP-Activated Protein Kinases; Animals; Cell Proliferation; Cysts; Disease Progression; Enzyme Activ

2021
Salvianolate Reduces Glucose Metabolism Disorders in Dimethylnitrosamine-Induced Cirrhotic Rats.
    Chinese journal of integrative medicine, 2018, Volume: 24, Issue:9

    Topics: Animals; Dimethylnitrosamine; Glucose; Glucose Tolerance Test; Insulin Resistance; Liver; Liver Cirr

2018
Metformin improves hepatic IRS2/PI3K/Akt signaling in insulin-resistant rats of NASH and cirrhosis.
    The Journal of endocrinology, 2016, Volume: 229, Issue:2

    Topics: Animals; Glucose Intolerance; Hypoglycemic Agents; Insulin Receptor Substrate Proteins; Insulin Resi

2016
[Effect of metformin on the formation of hepatic fibrosis in type 2 diabetic rats].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2010, Volume: 45, Issue:6

    Topics: Actins; Animals; Apoptosis; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetes Me

2010