metformin has been researched along with Chondrosarcoma in 1 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Chondrosarcoma: A slowly growing malignant neoplasm derived from cartilage cells, occurring most frequently in pelvic bones or near the ends of long bones, in middle-aged and old people. Most chondrosarcomas arise de novo, but some may develop in a preexisting benign cartilaginous lesion or in patients with ENCHONDROMATOSIS. (Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Ten chondrosarcoma cell lines were treated with the metabolic compounds CB-849, metformin, phenformin (lipophilic analogue of metformin) and chloroquine." | 3.88 | Targeting glutaminolysis in chondrosarcoma in context of the IDH1/2 mutation. ( Addie, RD; Bovée, JVMG; Cleton-Jansen, AM; Cleven, AHG; de Jong, Y; Kruisselbrink, AB; Molenaar, RJ; Niessen, B; Peterse, EFP; van den Akker, BEWM, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Peterse, EFP | 1 |
| Niessen, B | 1 |
| Addie, RD | 1 |
| de Jong, Y | 1 |
| Cleven, AHG | 1 |
| Kruisselbrink, AB | 1 |
| van den Akker, BEWM | 1 |
| Molenaar, RJ | 1 |
| Cleton-Jansen, AM | 1 |
| Bovée, JVMG | 1 |
1 other study available for metformin and Chondrosarcoma
| Article | Year |
|---|---|
Targeting glutaminolysis in chondrosarcoma in context of the IDH1/2 mutation.
Topics: Antineoplastic Agents; Benzeneacetamides; Bone Neoplasms; Chloroquine; Chondrosarcoma; Drug Screenin | 2018 |