Page last updated: 2024-10-30

metformin and Cerebral Hemorrhage

metformin has been researched along with Cerebral Hemorrhage in 6 studies

Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.

Cerebral Hemorrhage: Bleeding into one or both CEREBRAL HEMISPHERES including the BASAL GANGLIA and the CEREBRAL CORTEX. It is often associated with HYPERTENSION and CRANIOCEREBRAL TRAUMA.

Research Excerpts

ExcerptRelevanceReference
"Although recent studies have focused on the use of metformin in treating ischemic stroke, there is little literature to support whether it can treat intracerebral hemorrhage (ICH)."8.02Prestroke Metformin Use on the 1-Year Prognosis of Intracerebral Hemorrhage Patients with Type 2 Diabetes. ( Liu, Q; Sun, BL; Tu, WJ; Wang, K; Wang, Y; Zeng, Q; Zeng, X, 2021)
"The study aimed to evaluate the impact of D3 on the COS-markers and matrix metalloproteinases MMP2/MMP9 activity after acute intracerebral hemorrhage (ICH) in rats with experimental type 2 diabetes mellitus (Т2DM) compared to metformin (Met)."4.31Impact of Vitamin D3 on Carbonyl-Oxidative Stress and Matrix Metalloproteinases after Acute Intracerebral Hemorrhage in Rats with Type 2 Diabetes Mellitus. ( Dovban, O; Kharchenko, Y; Kovalchuk, Y; Lievykh, A; Shevtsova, A; Tkachenko, V; Ushakova, G; Zhyliuk, V, 2023)
"Although recent studies have focused on the use of metformin in treating ischemic stroke, there is little literature to support whether it can treat intracerebral hemorrhage (ICH)."4.02Prestroke Metformin Use on the 1-Year Prognosis of Intracerebral Hemorrhage Patients with Type 2 Diabetes. ( Liu, Q; Sun, BL; Tu, WJ; Wang, K; Wang, Y; Zeng, Q; Zeng, X, 2021)
"Metformin treatment ameliorated hydrocephalus and upregulated VE-cadherin expression in choroid plexus meanwhile."1.72Metformin Preserves VE-Cadherin in Choroid Plexus and Attenuates Hydrocephalus via VEGF/VEGFR2/p-Src in an Intraventricular Hemorrhage Rat Model. ( Gao, F; Hao, X; Jin, L; Jin, Y; Li, J; Shen, D; Tong, L; Ye, X, 2022)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (33.33)24.3611
2020's4 (66.67)2.80

Authors

AuthorsStudies
Lin, C1
Yang, K1
Zhang, G1
Yu, J1
Tu, WJ1
Zeng, Q1
Wang, K1
Wang, Y1
Sun, BL1
Zeng, X1
Liu, Q1
Shen, D1
Ye, X1
Li, J1
Hao, X1
Jin, L1
Jin, Y1
Tong, L1
Gao, F1
Lievykh, A1
Zhyliuk, V1
Ushakova, G1
Tkachenko, V1
Kovalchuk, Y1
Dovban, O1
Kharchenko, Y1
Shevtsova, A1
Qi, B1
Hu, L1
Zhu, L1
Shang, L1
Wang, X1
Liu, N1
Wen, N1
Hong, Y1
Fang, D1
Savadogo, M1
Millogo, GR1
Zabsonré, S1

Other Studies

6 other studies available for metformin and Cerebral Hemorrhage

ArticleYear
Metformin Ameliorates Neuronal Necroptosis after Intracerebral Hemorrhage by Activating AMPK.
    Current neurovascular research, 2021, Volume: 18, Issue:3

    Topics: AMP-Activated Protein Kinases; Cerebral Hemorrhage; Diabetes Mellitus, Type 2; Humans; Metformin; Ne

2021
Prestroke Metformin Use on the 1-Year Prognosis of Intracerebral Hemorrhage Patients with Type 2 Diabetes.
    Oxidative medicine and cellular longevity, 2021, Volume: 2021

    Topics: Adult; Aged; Biomarkers; Blood Glucose; Cerebral Hemorrhage; Diabetes Mellitus, Type 2; Female; Foll

2021
Metformin Preserves VE-Cadherin in Choroid Plexus and Attenuates Hydrocephalus via VEGF/VEGFR2/p-Src in an Intraventricular Hemorrhage Rat Model.
    International journal of molecular sciences, 2022, Aug-02, Volume: 23, Issue:15

    Topics: Animals; Antigens, CD; Cadherins; Cerebral Hemorrhage; Choroid Plexus; Hydrocephalus; Metformin; Pro

2022
Impact of Vitamin D3 on Carbonyl-Oxidative Stress and Matrix Metalloproteinases after Acute Intracerebral Hemorrhage in Rats with Type 2 Diabetes Mellitus.
    Endocrine, metabolic & immune disorders drug targets, 2023, Volume: 23, Issue:10

    Topics: Advanced Oxidation Protein Products; Animals; Biomarkers; Cerebral Hemorrhage; Cholecalciferol; Diab

2023
Metformin Attenuates Neurological Deficit after Intracerebral Hemorrhage by Inhibiting Apoptosis, Oxidative Stress and Neuroinflammation in Rats.
    Neurochemical research, 2017, Volume: 42, Issue:10

    Topics: Animals; Antioxidants; Apoptosis; Brain Injuries; Cerebral Hemorrhage; Disease Models, Animal; Infla

2017
[A hemorrhagic stroke revealing Neisseria meningitidis meningitis].
    The Pan African medical journal, 2015, Volume: 20

    Topics: Ceftriaxone; Cerebral Hemorrhage; Emergencies; Ethmoid Sinusitis; Female; Humans; Hydrocephalus; Hyp

2015