metformin has been researched along with Cat Diseases in 2 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Cat Diseases: Diseases of the domestic cat (Felis catus or F. domesticus). This term does not include diseases of the so-called big cats such as CHEETAHS; LIONS; tigers, cougars, panthers, leopards, and other Felidae for which the heading CARNIVORA is used.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metformin is an oral hypoglycemic drug that has been shown to inhibit cancer cell proliferation via up-regulation of AMPK (AMP-activated protein kinase), and possibly inhibition of mTOR (mammalian target of rapamycin)." | 5.46 | Anti-proliferative effect of metformin on a feline injection site sarcoma cell line independent of Mtor inhibition. ( Gogal, R; Hoover, K; Karpuzoglu, E; McLean, K; Pierro, J; Prater, R; Saba, C; Williams, R, 2017) |
| "Metformin is an oral hypoglycemic drug that has been shown to inhibit cancer cell proliferation via up-regulation of AMPK (AMP-activated protein kinase), and possibly inhibition of mTOR (mammalian target of rapamycin)." | 1.46 | Anti-proliferative effect of metformin on a feline injection site sarcoma cell line independent of Mtor inhibition. ( Gogal, R; Hoover, K; Karpuzoglu, E; McLean, K; Pierro, J; Prater, R; Saba, C; Williams, R, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pierro, J | 1 |
| Saba, C | 1 |
| McLean, K | 1 |
| Williams, R | 1 |
| Karpuzoglu, E | 1 |
| Prater, R | 1 |
| Hoover, K | 1 |
| Gogal, R | 1 |
| Wypij, JM | 1 |
2 other studies available for metformin and Cat Diseases
| Article | Year |
|---|---|
Anti-proliferative effect of metformin on a feline injection site sarcoma cell line independent of Mtor inhibition.
Topics: Animals; Apoptosis; Cat Diseases; Cats; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Re | 2017 |
Pilot study of oral metformin in cancer-bearing cats.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Cat Diseases; Cats; Female; Insulin-Like Growt | 2017 |