metformin has been researched along with Carotid Arteriopathies, Traumatic in 2 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metformin increased insulin sensitivity, but did not affect neointimal thickness in either the normal fat or high fat diet-fed rats." | 7.85 | High-dose metformin (420mg/kg daily p.o.) increases insulin sensitivity but does not affect neointimal thickness in the rat carotid balloon injury model of restenosis. ( Breen, DM; Dalvi, P; Dolinsky, VW; Giacca, A; Guo, J; Lam, L; Pereira, TJ; Swain, N; Yeung, LSN, 2017) |
| "Treatment with metformin significantly attenuates neointimal hyperplasia through inhibition of smooth muscle cell proliferation, migration, and inflammation as well as by improvement of the insulin signaling pathway." | 5.39 | The protective effect and underlying mechanism of metformin on neointima formation in fructose-induced insulin resistant rats. ( Adeli, K; Ji, J; Jiang, B; Liu, L; Lu, J; Meng, H; Meng, QH; Randell, E; Wang, D, 2013) |
| "Metformin increased insulin sensitivity, but did not affect neointimal thickness in either the normal fat or high fat diet-fed rats." | 3.85 | High-dose metformin (420mg/kg daily p.o.) increases insulin sensitivity but does not affect neointimal thickness in the rat carotid balloon injury model of restenosis. ( Breen, DM; Dalvi, P; Dolinsky, VW; Giacca, A; Guo, J; Lam, L; Pereira, TJ; Swain, N; Yeung, LSN, 2017) |
| "Treatment with metformin significantly attenuates neointimal hyperplasia through inhibition of smooth muscle cell proliferation, migration, and inflammation as well as by improvement of the insulin signaling pathway." | 1.39 | The protective effect and underlying mechanism of metformin on neointima formation in fructose-induced insulin resistant rats. ( Adeli, K; Ji, J; Jiang, B; Liu, L; Lu, J; Meng, H; Meng, QH; Randell, E; Wang, D, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lu, J | 1 |
| Ji, J | 1 |
| Meng, H | 1 |
| Wang, D | 1 |
| Jiang, B | 1 |
| Liu, L | 1 |
| Randell, E | 1 |
| Adeli, K | 1 |
| Meng, QH | 1 |
| Guo, J | 1 |
| Pereira, TJ | 1 |
| Dalvi, P | 1 |
| Yeung, LSN | 1 |
| Swain, N | 1 |
| Breen, DM | 1 |
| Lam, L | 1 |
| Dolinsky, VW | 1 |
| Giacca, A | 1 |
2 other studies available for metformin and Carotid Arteriopathies, Traumatic
| Article | Year |
|---|---|
The protective effect and underlying mechanism of metformin on neointima formation in fructose-induced insulin resistant rats.
Topics: Animals; Blood Glucose; Carotid Arteries; Carotid Artery Injuries; Carotid Stenosis; Cells, Cultured | 2013 |
High-dose metformin (420mg/kg daily p.o.) increases insulin sensitivity but does not affect neointimal thickness in the rat carotid balloon injury model of restenosis.
Topics: AMP-Activated Protein Kinases; Animals; Blood Pressure; Carotid Artery Injuries; Carotid Intima-Medi | 2017 |