Page last updated: 2024-10-30

metformin and Cardiovascular Pregnancy Complications

metformin has been researched along with Cardiovascular Pregnancy Complications in 4 studies

Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.

Research Excerpts

ExcerptRelevanceReference
"To review pregnancy outcomes in women with Type 2 diabetes (Type 2 DM), comparing women treated with those not treated with metformin."7.73Pregnancy in women with Type 2 diabetes: who takes metformin and what is the outcome? ( Hughes, RC; Rowan, JA, 2006)
" She would like to know whether she can continue using metformin during the pregnancy and also is concerned about the effect of the gastric bypass surgery."3.74A 40-year-old woman with diabetes contemplating pregnancy after gastric bypass surgery. ( Coustan, DR, 2008)
"To review pregnancy outcomes in women with Type 2 diabetes (Type 2 DM), comparing women treated with those not treated with metformin."3.73Pregnancy in women with Type 2 diabetes: who takes metformin and what is the outcome? ( Hughes, RC; Rowan, JA, 2006)
"Metformin is a logical treatment for women with gestational diabetes mellitus, but randomized trials to assess the efficacy and safety of its use for this condition are lacking."2.73Metformin versus insulin for the treatment of gestational diabetes. ( Battin, MR; Gao, W; Hague, WM; Moore, MP; Rowan, JA, 2008)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lundberg, GD1
Hughes, RC1
Rowan, JA2
Coustan, DR1
Hague, WM1
Gao, W1
Battin, MR1
Moore, MP1

Clinical Trials (6)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Glyburide and Metformin for the Treatment of Gestational Diabetes Mellitus. A Systematic Review and Meta-analysis of Randomized Controlled Trials Comparing These Drugs Either vs Insulin or vs Each Other.[NCT01998113]2,509 participants (Actual)Observational2013-03-31Completed
Does Metformin Improve Pregnancy Outcomes (Incidence of LGA (≥90% Birth Weight Centile) Babies, Onset of Maternal GDM, Hypertension, PET, Macrosomia, Shoulder Dystocia, Admission to SCBU) in Obese Non-diabetic Women?[NCT01273584]Phase 2/Phase 3450 participants (Actual)Interventional2010-10-31Completed
Prevention of Pre-eclampsia Using Metformin: a Randomized Control Trial[NCT04855513]414 participants (Anticipated)Interventional2022-03-24Not yet recruiting
Effect of Metformin on Healthy Live Birth After In-vitro Fertilization in Women With Prediabetes Mellitus: a Multicenter Double-blind Placebo Controlled Randomized Trial[NCT06064669]988 participants (Anticipated)Interventional2023-10-01Not yet recruiting
Preventing Recurrent Gestational Diabetes Mellitus With Early Metformin Intervention[NCT02394158]Phase 4112 participants (Anticipated)Interventional2015-01-27Recruiting
Non-inferiority Between Acarbose and Prandial Insulin for the Treatment of Gestational Diabetes Mellitus: a Randomized Multicenter and Prospective Trial. ACARB-GDM Study.[NCT03380546]Phase 3341 participants (Actual)Interventional2018-07-04Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for metformin and Cardiovascular Pregnancy Complications

ArticleYear
Metformin versus insulin for the treatment of gestational diabetes.
    The New England journal of medicine, 2008, May-08, Volume: 358, Issue:19

    Topics: Adult; Diabetes, Gestational; Drug Therapy, Combination; Female; Gestational Age; Humans; Hypoglycem

2008
Metformin versus insulin for the treatment of gestational diabetes.
    The New England journal of medicine, 2008, May-08, Volume: 358, Issue:19

    Topics: Adult; Diabetes, Gestational; Drug Therapy, Combination; Female; Gestational Age; Humans; Hypoglycem

2008
Metformin versus insulin for the treatment of gestational diabetes.
    The New England journal of medicine, 2008, May-08, Volume: 358, Issue:19

    Topics: Adult; Diabetes, Gestational; Drug Therapy, Combination; Female; Gestational Age; Humans; Hypoglycem

2008
Metformin versus insulin for the treatment of gestational diabetes.
    The New England journal of medicine, 2008, May-08, Volume: 358, Issue:19

    Topics: Adult; Diabetes, Gestational; Drug Therapy, Combination; Female; Gestational Age; Humans; Hypoglycem

2008
Metformin versus insulin for the treatment of gestational diabetes.
    The New England journal of medicine, 2008, May-08, Volume: 358, Issue:19

    Topics: Adult; Diabetes, Gestational; Drug Therapy, Combination; Female; Gestational Age; Humans; Hypoglycem

2008
Metformin versus insulin for the treatment of gestational diabetes.
    The New England journal of medicine, 2008, May-08, Volume: 358, Issue:19

    Topics: Adult; Diabetes, Gestational; Drug Therapy, Combination; Female; Gestational Age; Humans; Hypoglycem

2008
Metformin versus insulin for the treatment of gestational diabetes.
    The New England journal of medicine, 2008, May-08, Volume: 358, Issue:19

    Topics: Adult; Diabetes, Gestational; Drug Therapy, Combination; Female; Gestational Age; Humans; Hypoglycem

2008
Metformin versus insulin for the treatment of gestational diabetes.
    The New England journal of medicine, 2008, May-08, Volume: 358, Issue:19

    Topics: Adult; Diabetes, Gestational; Drug Therapy, Combination; Female; Gestational Age; Humans; Hypoglycem

2008
Metformin versus insulin for the treatment of gestational diabetes.
    The New England journal of medicine, 2008, May-08, Volume: 358, Issue:19

    Topics: Adult; Diabetes, Gestational; Drug Therapy, Combination; Female; Gestational Age; Humans; Hypoglycem

2008
Metformin versus insulin for the treatment of gestational diabetes.
    The New England journal of medicine, 2008, May-08, Volume: 358, Issue:19

    Topics: Adult; Diabetes, Gestational; Drug Therapy, Combination; Female; Gestational Age; Humans; Hypoglycem

2008
Metformin versus insulin for the treatment of gestational diabetes.
    The New England journal of medicine, 2008, May-08, Volume: 358, Issue:19

    Topics: Adult; Diabetes, Gestational; Drug Therapy, Combination; Female; Gestational Age; Humans; Hypoglycem

2008
Metformin versus insulin for the treatment of gestational diabetes.
    The New England journal of medicine, 2008, May-08, Volume: 358, Issue:19

    Topics: Adult; Diabetes, Gestational; Drug Therapy, Combination; Female; Gestational Age; Humans; Hypoglycem

2008
Metformin versus insulin for the treatment of gestational diabetes.
    The New England journal of medicine, 2008, May-08, Volume: 358, Issue:19

    Topics: Adult; Diabetes, Gestational; Drug Therapy, Combination; Female; Gestational Age; Humans; Hypoglycem

2008
Metformin versus insulin for the treatment of gestational diabetes.
    The New England journal of medicine, 2008, May-08, Volume: 358, Issue:19

    Topics: Adult; Diabetes, Gestational; Drug Therapy, Combination; Female; Gestational Age; Humans; Hypoglycem

2008
Metformin versus insulin for the treatment of gestational diabetes.
    The New England journal of medicine, 2008, May-08, Volume: 358, Issue:19

    Topics: Adult; Diabetes, Gestational; Drug Therapy, Combination; Female; Gestational Age; Humans; Hypoglycem

2008
Metformin versus insulin for the treatment of gestational diabetes.
    The New England journal of medicine, 2008, May-08, Volume: 358, Issue:19

    Topics: Adult; Diabetes, Gestational; Drug Therapy, Combination; Female; Gestational Age; Humans; Hypoglycem

2008
Metformin versus insulin for the treatment of gestational diabetes.
    The New England journal of medicine, 2008, May-08, Volume: 358, Issue:19

    Topics: Adult; Diabetes, Gestational; Drug Therapy, Combination; Female; Gestational Age; Humans; Hypoglycem

2008
Metformin versus insulin for the treatment of gestational diabetes.
    The New England journal of medicine, 2008, May-08, Volume: 358, Issue:19

    Topics: Adult; Diabetes, Gestational; Drug Therapy, Combination; Female; Gestational Age; Humans; Hypoglycem

2008
Metformin versus insulin for the treatment of gestational diabetes.
    The New England journal of medicine, 2008, May-08, Volume: 358, Issue:19

    Topics: Adult; Diabetes, Gestational; Drug Therapy, Combination; Female; Gestational Age; Humans; Hypoglycem

2008
Metformin versus insulin for the treatment of gestational diabetes.
    The New England journal of medicine, 2008, May-08, Volume: 358, Issue:19

    Topics: Adult; Diabetes, Gestational; Drug Therapy, Combination; Female; Gestational Age; Humans; Hypoglycem

2008
Metformin versus insulin for the treatment of gestational diabetes.
    The New England journal of medicine, 2008, May-08, Volume: 358, Issue:19

    Topics: Adult; Diabetes, Gestational; Drug Therapy, Combination; Female; Gestational Age; Humans; Hypoglycem

2008
Metformin versus insulin for the treatment of gestational diabetes.
    The New England journal of medicine, 2008, May-08, Volume: 358, Issue:19

    Topics: Adult; Diabetes, Gestational; Drug Therapy, Combination; Female; Gestational Age; Humans; Hypoglycem

2008
Metformin versus insulin for the treatment of gestational diabetes.
    The New England journal of medicine, 2008, May-08, Volume: 358, Issue:19

    Topics: Adult; Diabetes, Gestational; Drug Therapy, Combination; Female; Gestational Age; Humans; Hypoglycem

2008
Metformin versus insulin for the treatment of gestational diabetes.
    The New England journal of medicine, 2008, May-08, Volume: 358, Issue:19

    Topics: Adult; Diabetes, Gestational; Drug Therapy, Combination; Female; Gestational Age; Humans; Hypoglycem

2008
Metformin versus insulin for the treatment of gestational diabetes.
    The New England journal of medicine, 2008, May-08, Volume: 358, Issue:19

    Topics: Adult; Diabetes, Gestational; Drug Therapy, Combination; Female; Gestational Age; Humans; Hypoglycem

2008
Metformin versus insulin for the treatment of gestational diabetes.
    The New England journal of medicine, 2008, May-08, Volume: 358, Issue:19

    Topics: Adult; Diabetes, Gestational; Drug Therapy, Combination; Female; Gestational Age; Humans; Hypoglycem

2008
Metformin versus insulin for the treatment of gestational diabetes.
    The New England journal of medicine, 2008, May-08, Volume: 358, Issue:19

    Topics: Adult; Diabetes, Gestational; Drug Therapy, Combination; Female; Gestational Age; Humans; Hypoglycem

2008
Metformin versus insulin for the treatment of gestational diabetes.
    The New England journal of medicine, 2008, May-08, Volume: 358, Issue:19

    Topics: Adult; Diabetes, Gestational; Drug Therapy, Combination; Female; Gestational Age; Humans; Hypoglycem

2008
Metformin versus insulin for the treatment of gestational diabetes.
    The New England journal of medicine, 2008, May-08, Volume: 358, Issue:19

    Topics: Adult; Diabetes, Gestational; Drug Therapy, Combination; Female; Gestational Age; Humans; Hypoglycem

2008
Metformin versus insulin for the treatment of gestational diabetes.
    The New England journal of medicine, 2008, May-08, Volume: 358, Issue:19

    Topics: Adult; Diabetes, Gestational; Drug Therapy, Combination; Female; Gestational Age; Humans; Hypoglycem

2008
Metformin versus insulin for the treatment of gestational diabetes.
    The New England journal of medicine, 2008, May-08, Volume: 358, Issue:19

    Topics: Adult; Diabetes, Gestational; Drug Therapy, Combination; Female; Gestational Age; Humans; Hypoglycem

2008
Metformin versus insulin for the treatment of gestational diabetes.
    The New England journal of medicine, 2008, May-08, Volume: 358, Issue:19

    Topics: Adult; Diabetes, Gestational; Drug Therapy, Combination; Female; Gestational Age; Humans; Hypoglycem

2008
Metformin versus insulin for the treatment of gestational diabetes.
    The New England journal of medicine, 2008, May-08, Volume: 358, Issue:19

    Topics: Adult; Diabetes, Gestational; Drug Therapy, Combination; Female; Gestational Age; Humans; Hypoglycem

2008
Metformin versus insulin for the treatment of gestational diabetes.
    The New England journal of medicine, 2008, May-08, Volume: 358, Issue:19

    Topics: Adult; Diabetes, Gestational; Drug Therapy, Combination; Female; Gestational Age; Humans; Hypoglycem

2008
Metformin versus insulin for the treatment of gestational diabetes.
    The New England journal of medicine, 2008, May-08, Volume: 358, Issue:19

    Topics: Adult; Diabetes, Gestational; Drug Therapy, Combination; Female; Gestational Age; Humans; Hypoglycem

2008
Metformin versus insulin for the treatment of gestational diabetes.
    The New England journal of medicine, 2008, May-08, Volume: 358, Issue:19

    Topics: Adult; Diabetes, Gestational; Drug Therapy, Combination; Female; Gestational Age; Humans; Hypoglycem

2008

Other Studies

3 other studies available for metformin and Cardiovascular Pregnancy Complications

ArticleYear
Metformin Trumps insulin in the treatment of gestational diabetes.
    Medscape journal of medicine, 2008, Jul-31, Volume: 10, Issue:7

    Topics: Adult; Diabetes, Gestational; Drug Therapy, Combination; Female; Gestational Age; Humans; Hypoglycem

2008
Pregnancy in women with Type 2 diabetes: who takes metformin and what is the outcome?
    Diabetic medicine : a journal of the British Diabetic Association, 2006, Volume: 23, Issue:3

    Topics: Adult; Body Mass Index; Chronic Disease; Delivery, Obstetric; Diabetes Mellitus, Type 2; Female; Fet

2006
A 40-year-old woman with diabetes contemplating pregnancy after gastric bypass surgery.
    JAMA, 2008, Jun-04, Volume: 299, Issue:21

    Topics: Adult; Antihypertensive Agents; Breast Feeding; Diabetes Mellitus, Type 2; Female; Gastric Bypass; G

2008