metformin has been researched along with Carcinoma 256, Walker in 4 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Carcinoma 256, Walker: A transplantable carcinoma of the rat that originally appeared spontaneously in the mammary gland of a pregnant albino rat, and which now resembles a carcinoma in young transplants and a sarcoma in older transplants. (Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metformin treatment not only decreases the tumour growth but also improves the protein metabolism in gastrocnemius muscle in tumour-bearing rats." | 5.43 | Metformin treatment modulates the tumour-induced wasting effects in muscle protein metabolism minimising the cachexia in tumour-bearing rats. ( Gomes-Marcondes, MC; Oliveira, AG, 2016) |
| "Our data allow us to suggest that metformin, reducing the stimulatory effect of obesity on tumor development, has a potential role in the management of cancers." | 3.81 | Metformin reduces the Walker-256 tumor development in obese-MSG rats via AMPK and FOXO3a. ( Akamine, EH; de Carvalho, MH; de Queiroz, EA; Fortes, ZB; Sampaio, SC, 2015) |
| "Chronic metformin treatment improved the glycemic homeostasis in pre-diabetic MSG-rats, glucose intolerance, tissue insulin resistance, hyperinsulinemia and decreased the fat tissue accretion." | 3.80 | Protective effect of metformin against walker 256 tumor growth is not dependent on metabolism improvement. ( Agostinho, AR; Barella, LF; Beraldi, EJ; de Castro Prado, MA; de Oliveira, JC; de Sant'Anna, JR; de Souza, CO; de Souza, HM; Franco, CC; Gravena, C; Malta, A; Mathias, PC; Miranda, RA; Prates, KV; Tófolo, LP; Torrezan, R; Trombini, AB, 2014) |
| "Metformin treatment not only decreases the tumour growth but also improves the protein metabolism in gastrocnemius muscle in tumour-bearing rats." | 1.43 | Metformin treatment modulates the tumour-induced wasting effects in muscle protein metabolism minimising the cachexia in tumour-bearing rats. ( Gomes-Marcondes, MC; Oliveira, AG, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| de Queiroz, EA | 1 |
| Akamine, EH | 2 |
| de Carvalho, MH | 2 |
| Sampaio, SC | 1 |
| Fortes, ZB | 2 |
| Franco, CC | 1 |
| Miranda, RA | 1 |
| de Oliveira, JC | 1 |
| Barella, LF | 1 |
| Agostinho, AR | 1 |
| Prates, KV | 1 |
| Malta, A | 1 |
| Trombini, AB | 1 |
| Torrezan, R | 1 |
| Gravena, C | 1 |
| Tófolo, LP | 1 |
| de Sant'Anna, JR | 1 |
| de Castro Prado, MA | 1 |
| de Souza, CO | 1 |
| de Souza, HM | 1 |
| Beraldi, EJ | 1 |
| Mathias, PC | 1 |
| Oliveira, AG | 1 |
| Gomes-Marcondes, MC | 1 |
| Fonseca, EA | 1 |
| de Oliveira, MA | 1 |
| Lobato, Nde S | 1 |
| Colquhoun, A | 1 |
| Zyngier, SB | 1 |
4 other studies available for metformin and Carcinoma 256, Walker
| Article | Year |
|---|---|
Metformin reduces the Walker-256 tumor development in obese-MSG rats via AMPK and FOXO3a.
Topics: Animals; Carcinoma 256, Walker; Cyclic AMP-Dependent Protein Kinases; Female; Food Additives; Forkhe | 2015 |
Protective effect of metformin against walker 256 tumor growth is not dependent on metabolism improvement.
Topics: Animals; Blood Glucose; Carcinoma 256, Walker; Cell Proliferation; Diabetes Mellitus, Experimental; | 2014 |
Metformin treatment modulates the tumour-induced wasting effects in muscle protein metabolism minimising the cachexia in tumour-bearing rats.
Topics: Animals; Body Composition; Cachexia; Carcinoma 256, Walker; Cell Line, Tumor; Cell Proliferation; Ge | 2016 |
Metformin reduces the stimulatory effect of obesity on in vivo Walker-256 tumor development and increases the area of tumor necrosis.
Topics: Animals; Carcinoma 256, Walker; Male; Metformin; Necrosis; Obesity; Random Allocation; Rats; Rats, W | 2011 |