metformin has been researched along with Calcinosis in 5 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Calcinosis: Pathologic deposition of calcium salts in tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Methods and Results The Diabetes Prevention Program was a randomized controlled trial comparing an intensive lifestyle intervention, metformin, or placebo for prevention of type 2 diabetes among patients with prediabetes." | 5.69 | Coronary Artery Calcium and Cognitive Decline in the Diabetes Prevention Program Outcomes Study. ( Crandall, JP; Dabelea, D; Gadde, KM; Goldberg, RB; Ibebuogu, UN; Luchsinger, JA; Orchard, TJ; Pi-Sunyer, FX; Schlögl, M; Temprosa, M; Watson, KE; Yin, X, 2023) |
| "Metformin treatment ameliorated AVICs calcification and apoptosis by activating the PI3K/AKT signaling pathway." | 1.62 | Metformin alleviates the calcification of aortic valve interstitial cells through activating the PI3K/AKT pathway in an AMPK dependent way. ( En, Q; Wei, W; Xu, W; Yuetang, W; Zeping, H, 2021) |
| "Metformin usage was independently associated with lower CAC scores in T2DM patients." | 1.51 | Association between Metformin Use and Coronary Artery Calcification in Type 2 Diabetic Patients. ( Cai, Z; Chen, Z; Lu, Y; Sun, X; Wang, Y; Wei, J; Weng, T; Xiang, M, 2019) |
| "HFD successfully induces gallstone (4 out of 4 of the HFD members)." | 1.48 | Metformin treatment prevents gallstone formation but mimics porcelain gallbladder in C57Bl/6 mice. ( Dehghanian, A; Dorvash, MR; Firouzabadi, N; Khoshnood, MJ; Mosaddeghi, P; Saber, H, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 2 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| En, Q | 1 |
| Zeping, H | 1 |
| Yuetang, W | 1 |
| Xu, W | 1 |
| Wei, W | 1 |
| Gadde, KM | 1 |
| Yin, X | 1 |
| Goldberg, RB | 1 |
| Orchard, TJ | 1 |
| Schlögl, M | 1 |
| Dabelea, D | 1 |
| Ibebuogu, UN | 1 |
| Watson, KE | 1 |
| Pi-Sunyer, FX | 1 |
| Crandall, JP | 1 |
| Temprosa, M | 1 |
| Luchsinger, JA | 1 |
| Dorvash, MR | 1 |
| Khoshnood, MJ | 1 |
| Saber, H | 1 |
| Dehghanian, A | 1 |
| Mosaddeghi, P | 1 |
| Firouzabadi, N | 1 |
| Lu, Y | 1 |
| Wang, Y | 1 |
| Weng, T | 1 |
| Chen, Z | 1 |
| Sun, X | 1 |
| Wei, J | 1 |
| Cai, Z | 1 |
| Xiang, M | 1 |
| Bhasin, DK | 1 |
| Sidhu, RS | 1 |
| Bhansali, A | 1 |
| Nagi, B | 1 |
1 trial available for metformin and Calcinosis
| Article | Year |
|---|---|
Coronary Artery Calcium and Cognitive Decline in the Diabetes Prevention Program Outcomes Study.
Topics: Adult; Calcinosis; Calcium; Calcium, Dietary; Cognitive Dysfunction; Coronary Artery Disease; Corona | 2023 |
4 other studies available for metformin and Calcinosis
| Article | Year |
|---|---|
Metformin alleviates the calcification of aortic valve interstitial cells through activating the PI3K/AKT pathway in an AMPK dependent way.
Topics: AMP-Activated Protein Kinases; Aortic Valve; Aortic Valve Stenosis; Calcinosis; Cells, Cultured; Hum | 2021 |
Metformin treatment prevents gallstone formation but mimics porcelain gallbladder in C57Bl/6 mice.
Topics: Animals; Calcinosis; Cholagogues and Choleretics; Cholesterol; Diabetes Mellitus, Type 2; Diet, High | 2018 |
Association between Metformin Use and Coronary Artery Calcification in Type 2 Diabetic Patients.
Topics: Aged; Calcinosis; Coronary Artery Disease; Coronary Vessels; Cross-Sectional Studies; Diabetes Melli | 2019 |
Diabetic ketoacidosis in a patient with chronic calcific pancreatitis after minor papilla stent insertion.
Topics: Alcoholism; Calcinosis; Cholangiopancreatography, Endoscopic Retrograde; Chronic Disease; Diabetic K | 2004 |