Page last updated: 2024-10-30

metformin and Calcinosis

metformin has been researched along with Calcinosis in 5 studies

Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.

Calcinosis: Pathologic deposition of calcium salts in tissues.

Research Excerpts

ExcerptRelevanceReference
" Methods and Results The Diabetes Prevention Program was a randomized controlled trial comparing an intensive lifestyle intervention, metformin, or placebo for prevention of type 2 diabetes among patients with prediabetes."5.69Coronary Artery Calcium and Cognitive Decline in the Diabetes Prevention Program Outcomes Study. ( Crandall, JP; Dabelea, D; Gadde, KM; Goldberg, RB; Ibebuogu, UN; Luchsinger, JA; Orchard, TJ; Pi-Sunyer, FX; Schlögl, M; Temprosa, M; Watson, KE; Yin, X, 2023)
"Metformin treatment ameliorated AVICs calcification and apoptosis by activating the PI3K/AKT signaling pathway."1.62Metformin alleviates the calcification of aortic valve interstitial cells through activating the PI3K/AKT pathway in an AMPK dependent way. ( En, Q; Wei, W; Xu, W; Yuetang, W; Zeping, H, 2021)
"Metformin usage was independently associated with lower CAC scores in T2DM patients."1.51Association between Metformin Use and Coronary Artery Calcification in Type 2 Diabetic Patients. ( Cai, Z; Chen, Z; Lu, Y; Sun, X; Wang, Y; Wei, J; Weng, T; Xiang, M, 2019)
"HFD successfully induces gallstone (4 out of 4 of the HFD members)."1.48Metformin treatment prevents gallstone formation but mimics porcelain gallbladder in C57Bl/6 mice. ( Dehghanian, A; Dorvash, MR; Firouzabadi, N; Khoshnood, MJ; Mosaddeghi, P; Saber, H, 2018)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's2 (40.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
En, Q1
Zeping, H1
Yuetang, W1
Xu, W1
Wei, W1
Gadde, KM1
Yin, X1
Goldberg, RB1
Orchard, TJ1
Schlögl, M1
Dabelea, D1
Ibebuogu, UN1
Watson, KE1
Pi-Sunyer, FX1
Crandall, JP1
Temprosa, M1
Luchsinger, JA1
Dorvash, MR1
Khoshnood, MJ1
Saber, H1
Dehghanian, A1
Mosaddeghi, P1
Firouzabadi, N1
Lu, Y1
Wang, Y1
Weng, T1
Chen, Z1
Sun, X1
Wei, J1
Cai, Z1
Xiang, M1
Bhasin, DK1
Sidhu, RS1
Bhansali, A1
Nagi, B1

Trials

1 trial available for metformin and Calcinosis

ArticleYear
Coronary Artery Calcium and Cognitive Decline in the Diabetes Prevention Program Outcomes Study.
    Journal of the American Heart Association, 2023, 11-07, Volume: 12, Issue:21

    Topics: Adult; Calcinosis; Calcium; Calcium, Dietary; Cognitive Dysfunction; Coronary Artery Disease; Corona

2023

Other Studies

4 other studies available for metformin and Calcinosis

ArticleYear
Metformin alleviates the calcification of aortic valve interstitial cells through activating the PI3K/AKT pathway in an AMPK dependent way.
    Molecular medicine (Cambridge, Mass.), 2021, 12-11, Volume: 27, Issue:1

    Topics: AMP-Activated Protein Kinases; Aortic Valve; Aortic Valve Stenosis; Calcinosis; Cells, Cultured; Hum

2021
Metformin treatment prevents gallstone formation but mimics porcelain gallbladder in C57Bl/6 mice.
    European journal of pharmacology, 2018, Aug-15, Volume: 833

    Topics: Animals; Calcinosis; Cholagogues and Choleretics; Cholesterol; Diabetes Mellitus, Type 2; Diet, High

2018
Association between Metformin Use and Coronary Artery Calcification in Type 2 Diabetic Patients.
    Journal of diabetes research, 2019, Volume: 2019

    Topics: Aged; Calcinosis; Coronary Artery Disease; Coronary Vessels; Cross-Sectional Studies; Diabetes Melli

2019
Diabetic ketoacidosis in a patient with chronic calcific pancreatitis after minor papilla stent insertion.
    Gastrointestinal endoscopy, 2004, Volume: 59, Issue:3

    Topics: Alcoholism; Calcinosis; Cholangiopancreatography, Endoscopic Retrograde; Chronic Disease; Diabetic K

2004