metformin has been researched along with Bronchopulmonary Dysplasia in 2 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Bronchopulmonary Dysplasia: A chronic lung disease developed after OXYGEN INHALATION THERAPY or mechanical ventilation (VENTILATION, MECHANICAL) usually occurring in certain premature infants (INFANT, PREMATURE) or newborn infants with respiratory distress syndrome (RESPIRATORY DISTRESS SYNDROME, NEWBORN). Histologically, it is characterized by the unusual abnormalities of the bronchioles, such as METAPLASIA, decrease in alveolar number, and formation of CYSTS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metformin has potential anti-inflammatory properties and accelerates wound healing by enhancing vascular development." | 5.72 | Metformin regulates macrophage polarization via the Shh signaling pathway to improve pulmonary vascular development in bronchopulmonary dysplasia. ( Chen, Y; Lin, Z; Qu, X; Xia, H; Xiang, X; Zhou, L, 2022) |
| "Metformin has potential anti-inflammatory properties and accelerates wound healing by enhancing vascular development." | 1.72 | Metformin regulates macrophage polarization via the Shh signaling pathway to improve pulmonary vascular development in bronchopulmonary dysplasia. ( Chen, Y; Lin, Z; Qu, X; Xia, H; Xiang, X; Zhou, L, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xiang, X | 1 |
| Zhou, L | 1 |
| Lin, Z | 1 |
| Qu, X | 1 |
| Chen, Y | 1 |
| Xia, H | 1 |
| Chen, X | 1 |
| Walther, FJ | 1 |
| Sengers, RM | 1 |
| Laghmani, el H | 1 |
| Salam, A | 1 |
| Folkerts, G | 1 |
| Pera, T | 1 |
| Wagenaar, GT | 1 |
2 other studies available for metformin and Bronchopulmonary Dysplasia
| Article | Year |
|---|---|
Metformin regulates macrophage polarization via the Shh signaling pathway to improve pulmonary vascular development in bronchopulmonary dysplasia.
Topics: Animals; Bronchopulmonary Dysplasia; Cell Polarity; Hedgehog Proteins; Hyperoxia; Inflammation; Lung | 2022 |
Metformin attenuates hyperoxia-induced lung injury in neonatal rats by reducing the inflammatory response.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents; Bronchopulmonary Dysplasia; Capillary Permeabil | 2015 |