metformin has been researched along with Brain Edema in 1 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metformin treatment after SAH promoted mitophagy in an AMPK-dependent manner." | 5.72 | Metformin attenuates early brain injury after subarachnoid hemorrhage in rats via AMPK-dependent mitophagy. ( Guo, Y; Li, Y; Liu, B; Shi, H; Tian, Y; Wu, P; Zhang, T; Zhang, Y, 2022) |
| "Metformin treatment after SAH promoted mitophagy in an AMPK-dependent manner." | 1.72 | Metformin attenuates early brain injury after subarachnoid hemorrhage in rats via AMPK-dependent mitophagy. ( Guo, Y; Li, Y; Liu, B; Shi, H; Tian, Y; Wu, P; Zhang, T; Zhang, Y, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, Y | 1 |
| Zhang, T | 1 |
| Li, Y | 1 |
| Guo, Y | 1 |
| Liu, B | 1 |
| Tian, Y | 1 |
| Wu, P | 1 |
| Shi, H | 1 |
1 other study available for metformin and Brain Edema
| Article | Year |
|---|---|
Metformin attenuates early brain injury after subarachnoid hemorrhage in rats via AMPK-dependent mitophagy.
Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Blood-Brain Barrier; Brain Edema; Brain Injuries; | 2022 |