metformin has been researched along with Blood Pressure, Low in 11 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metformin accumulation is associated with lactic acidosis and haemodynamic instability." | 8.31 | [Metformin-associated lactic acidosis]. ( Arthurson, C; Fjære, OL; Morberg, PCW; Ringdal, KG, 2023) |
| "Metformin is an antidiabetic drug; used to treat type II diabetes mellitus, metformin associated lactic acidosis has an incidence of 2-9 cases / 100,000 patients / year with high mortality (30%)." | 7.88 | [A case of severe metformin-associated lactic acidosis treated with CVVHDF and regional anticoagulation with sodium citrate]. ( Apicella, A; Beretta, E; Della Morte, M; Ferrario, M, 2018) |
| "Lactic acidosis is a well-recognized consequence of metformin." | 7.79 | Metformin overdose-induced hypoglycemia in the absence of other antidiabetic drugs. ( Al-Abri, SA; Hayashi, S; Olson, KR; Thoren, KL, 2013) |
| "Metformin-associated lactic acidosis (MALA) is well described in patients taking therapeutic metformin who develop renal failure or other serious comorbid conditions." | 7.76 | Can acute overdose of metformin lead to lactic acidosis? ( Bryant, SM; Buckley, P; Seo, B; Wills, BK, 2010) |
| "Metformin has been shown to modulate the cardiovascular response to intraduodenal glucose in patients with type 2 diabetes (T2DM), and may have the capacity to regulate postprandial blood pressure (BP), which is often inadequately compensated in T2DM, resulting in postprandial hypotension." | 5.30 | Metformin attenuates the postprandial fall in blood pressure in type 2 diabetes. ( Borg, MJ; Horowitz, M; Jones, KL; Rayner, CK; Sun, Z; Wu, T, 2019) |
| "Metformin accumulation is associated with lactic acidosis and haemodynamic instability." | 4.31 | [Metformin-associated lactic acidosis]. ( Arthurson, C; Fjære, OL; Morberg, PCW; Ringdal, KG, 2023) |
| "Metformin is an antidiabetic drug; used to treat type II diabetes mellitus, metformin associated lactic acidosis has an incidence of 2-9 cases / 100,000 patients / year with high mortality (30%)." | 3.88 | [A case of severe metformin-associated lactic acidosis treated with CVVHDF and regional anticoagulation with sodium citrate]. ( Apicella, A; Beretta, E; Della Morte, M; Ferrario, M, 2018) |
| "Lactic acidosis is a well-recognized consequence of metformin." | 3.79 | Metformin overdose-induced hypoglycemia in the absence of other antidiabetic drugs. ( Al-Abri, SA; Hayashi, S; Olson, KR; Thoren, KL, 2013) |
| "Metformin-associated lactic acidosis (MALA) is well described in patients taking therapeutic metformin who develop renal failure or other serious comorbid conditions." | 3.76 | Can acute overdose of metformin lead to lactic acidosis? ( Bryant, SM; Buckley, P; Seo, B; Wills, BK, 2010) |
| "Metformin, widely used in the treatment of diabetes mellitus, is known to cause lactic acidosis in both therapeutic use and after an overdose." | 3.76 | Metformin overdose with a resultant serum pH of 6.59: survival without sequalae. ( Algren, DA; Dell'Aglio, DM; Morgan, BW; Perino, LJ; Todino, JD, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 7 (63.64) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Fjære, OL | 1 |
| Arthurson, C | 1 |
| Ringdal, KG | 1 |
| Morberg, PCW | 1 |
| Ferrario, M | 1 |
| Apicella, A | 1 |
| Della Morte, M | 1 |
| Beretta, E | 1 |
| Borg, MJ | 1 |
| Jones, KL | 1 |
| Sun, Z | 1 |
| Horowitz, M | 1 |
| Rayner, CK | 1 |
| Wu, T | 1 |
| Al-Abri, SA | 1 |
| Hayashi, S | 1 |
| Thoren, KL | 1 |
| Olson, KR | 1 |
| Ebrahim, I | 1 |
| Blockman, M | 1 |
| Wills, BK | 1 |
| Bryant, SM | 1 |
| Buckley, P | 1 |
| Seo, B | 1 |
| Miller, DK | 1 |
| Brinson, AJ | 1 |
| Catalano, G | 1 |
| Catalano, MC | 1 |
| Kazory, A | 1 |
| Walsh, K | 1 |
| Harman, E | 1 |
| Talor, Z | 1 |
| Dell'Aglio, DM | 1 |
| Perino, LJ | 1 |
| Todino, JD | 1 |
| Algren, DA | 1 |
| Morgan, BW | 1 |
| Muntzel, MS | 2 |
| Abe, A | 1 |
| Petersen, JS | 1 |
| Nyeduala, B | 1 |
| Barrett, S | 1 |
1 trial available for metformin and Blood Pressure, Low
| Article | Year |
|---|---|
Metformin attenuates the postprandial fall in blood pressure in type 2 diabetes.
Topics: Aged; Blood Pressure; Cross-Over Studies; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Ga | 2019 |
10 other studies available for metformin and Blood Pressure, Low
| Article | Year |
|---|---|
[Metformin-associated lactic acidosis].
Topics: Acidosis, Lactic; Aged; Bradycardia; Female; Humans; Hypoglycemic Agents; Hypotension; Metformin; Me | 2023 |
[A case of severe metformin-associated lactic acidosis treated with CVVHDF and regional anticoagulation with sodium citrate].
Topics: Acidosis, Lactic; Aged; Anticoagulants; Bronchial Spasm; Combined Modality Therapy; Female; Furosemi | 2018 |
Metformin overdose-induced hypoglycemia in the absence of other antidiabetic drugs.
Topics: Acidosis, Lactic; Adolescent; Drug Overdose; Female; Humans; Hypoglycemia; Hypoglycemic Agents; Hypo | 2013 |
Metabolic acidosis in a patient with metformin overdose.
Topics: Acidosis; Blood Gas Analysis; Cardiotonic Agents; Drug Overdose; Fatal Outcome; Female; Heart Arrest | 2017 |
Can acute overdose of metformin lead to lactic acidosis?
Topics: Acidosis, Lactic; Adolescent; Adult; Child; Child, Preschool; Drug Overdose; Female; Humans; Hypogly | 2010 |
Lactic acidosis, hypotension, and sensorineural hearing loss following intentional metformin overdose.
Topics: Acidosis, Lactic; Drug Overdose; Glyburide; Hearing Loss, Sensorineural; Humans; Hypoglycemia; Hypog | 2011 |
Is metformin safe in patients with mild renal insufficiency?
Topics: Diabetic Nephropathies; Humans; Hypoglycemic Agents; Hypotension; Lung Diseases; Male; Metformin; Mi | 2007 |
Metformin overdose with a resultant serum pH of 6.59: survival without sequalae.
Topics: Acidosis, Lactic; Adult; Drug Overdose; Female; Humans; Hypoglycemic Agents; Hypotension; Metformin; | 2010 |
Effects of adrenergic, cholinergic and ganglionic blockade on acute depressor responses to metformin in spontaneously hypertensive rats.
Topics: Adrenergic Antagonists; Animals; Cholinergic Antagonists; Enzyme Inhibitors; Ganglia; Hypoglycemic A | 1997 |
High dietary salt enhances acute depressor responses to metformin.
Topics: Animals; Blood Pressure; Drug Interactions; Heart Rate; Hypertension; Hypoglycemic Agents; Hypotensi | 1999 |