metformin has been researched along with Autism-Dementia-Ataxia-Loss of Purposeful Hand Use Syndrome in 1 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metformin is the most common anti-diabetic drug and a promising therapy for disorders beyond diabetes, including Rett syndrome (RTT), a rare neurologic disease characterized by severe intellectual disability." | 8.31 | Chronic treatment with the anti-diabetic drug metformin rescues impaired brain mitochondrial activity and selectively ameliorates defective cognitive flexibility in a female mouse model of Rett syndrome. ( Cosentino, L; De Filippis, B; Di Crescenzo, L; Di Domenico, F; Lanzillotta, C; Perluigi, M; Pietraforte, D; Prestia, F; Quattrini, MC; Urbinati, C; Vacca, RA; Valenti, D, 2023) |
| "Metformin is the most common anti-diabetic drug and a promising therapy for disorders beyond diabetes, including Rett syndrome (RTT), a rare neurologic disease characterized by severe intellectual disability." | 4.31 | Chronic treatment with the anti-diabetic drug metformin rescues impaired brain mitochondrial activity and selectively ameliorates defective cognitive flexibility in a female mouse model of Rett syndrome. ( Cosentino, L; De Filippis, B; Di Crescenzo, L; Di Domenico, F; Lanzillotta, C; Perluigi, M; Pietraforte, D; Prestia, F; Quattrini, MC; Urbinati, C; Vacca, RA; Valenti, D, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Urbinati, C | 3 |
| Lanzillotta, C | 3 |
| Cosentino, L | 3 |
| Valenti, D | 3 |
| Quattrini, MC | 3 |
| Di Crescenzo, L | 3 |
| Prestia, F | 3 |
| Pietraforte, D | 3 |
| Perluigi, M | 3 |
| Di Domenico, F | 3 |
| Vacca, RA | 3 |
| De Filippis, B | 3 |
1 other study available for metformin and Autism-Dementia-Ataxia-Loss of Purposeful Hand Use Syndrome