Page last updated: 2024-10-30

metformin and Aura

metformin has been researched along with Aura in 9 studies

Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.

Research Excerpts

ExcerptRelevanceReference
"Preclinical and clinical evidence involving metformin's role in epilepsy and special conditions like tuberous sclerosis have been reviewed in this paper."9.22A review on role of metformin as a potential drug for epilepsy treatment and modulation of epileptogenesis. ( Sarangi, SC; Singh, R; Singh, S; Tripathi, M, 2022)
"The present study was designed to examine the possible neuroprotective and antiepileptic effects of metformin (Metf) in a rat model of pentylenetetrazole (PTZ)-induced epilepsy and its possible underlying mechanisms."7.91Effects of metformin on apoptosis and α-synuclein in a rat model of pentylenetetrazole-induced epilepsy. ( Abbas, KM; Abulseoud, OA; Ali, AN; El-Mesery, M; El-Shafey, M; Eldosoky, M; Hussein, AM, 2019)
"Metformin is a drug in the family of biguanide compounds that is widely used in the treatment of type 2 diabetes (T2D)."6.72Beneficial Effects of Metformin on the Central Nervous System, with a Focus on Epilepsy and Lafora Disease. ( Sánchez, MP; Sanz, P; Serratosa, JM, 2021)
"Epilepsy is a neurological disorder characterized by an enduring predisposition to generate and aggravate epileptic seizures affecting around 1% of global population making it a serious health concern."6.61Envisioning the neuroprotective effect of Metformin in experimental epilepsy: A portrait of molecular crosstalk. ( H S, N; K L, K; Paudel, YN, 2019)
"Preclinical and clinical evidence involving metformin's role in epilepsy and special conditions like tuberous sclerosis have been reviewed in this paper."5.22A review on role of metformin as a potential drug for epilepsy treatment and modulation of epileptogenesis. ( Sarangi, SC; Singh, R; Singh, S; Tripathi, M, 2022)
"We searched PubMed, SCOPUS, Sciences Direct, and grey literature in order to explore articles published in English from January 2010 to November 2018, using key terms "epilepsy," "seizure," "metformin," "oral hypoglycemic agents," and "oral antidiabetic drugs"."5.01The Effect of Metformin in Experimentally Induced Animal Models of Epileptic Seizure. ( Gebre, AK; Surur, A; Wondafrash, DZ; Yimer, EM, 2019)
"The present study was designed to examine the possible neuroprotective and antiepileptic effects of metformin (Metf) in a rat model of pentylenetetrazole (PTZ)-induced epilepsy and its possible underlying mechanisms."3.91Effects of metformin on apoptosis and α-synuclein in a rat model of pentylenetetrazole-induced epilepsy. ( Abbas, KM; Abulseoud, OA; Ali, AN; El-Mesery, M; El-Shafey, M; Eldosoky, M; Hussein, AM, 2019)
"Metformin is a drug in the family of biguanide compounds that is widely used in the treatment of type 2 diabetes (T2D)."2.72Beneficial Effects of Metformin on the Central Nervous System, with a Focus on Epilepsy and Lafora Disease. ( Sánchez, MP; Sanz, P; Serratosa, JM, 2021)
"Epilepsy is a neurological disorder characterized by an enduring predisposition to generate and aggravate epileptic seizures affecting around 1% of global population making it a serious health concern."2.61Envisioning the neuroprotective effect of Metformin in experimental epilepsy: A portrait of molecular crosstalk. ( H S, N; K L, K; Paudel, YN, 2019)
"CA6 and CA12 (p."1.91Anticonvulsant Profile of Selected Medium-Chain Fatty Acids (MCFAs) Co-Administered with Metformin in Mice in Acute and Chronic Treatment. ( Nieoczym, D; Pieróg, M; Samorek-Pieróg, M; Socała, K; Wlaź, P; Wyska, E, 2023)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (44.44)24.3611
2020's5 (55.56)2.80

Authors

AuthorsStudies
Singh, R1
Sarangi, SC1
Singh, S1
Tripathi, M1
Jurca, CM1
Kozma, K1
Petchesi, CD1
Zaha, DC1
Magyar, I1
Munteanu, M1
Faur, L1
Jurca, A1
Bembea, D1
Severin, E1
Jurca, AD1
Pieróg, M1
Socała, K1
Nieoczym, D1
Wyska, E1
Samorek-Pieróg, M1
Wlaź, P1
Kopel, J1
Grooms, A1
Ganapathy, V1
Clothier, J1
Sanz, P1
Serratosa, JM1
Sánchez, MP1
Rubio Osornio, MDC1
Custodio Ramírez, V1
Calderón Gámez, D1
Paz Tres, C1
Carvajal Aguilera, KG1
Phillips Farfán, BV1
Hussein, AM1
Eldosoky, M1
El-Shafey, M1
El-Mesery, M1
Ali, AN1
Abbas, KM1
Abulseoud, OA1
Yimer, EM1
Surur, A1
Wondafrash, DZ1
Gebre, AK1
H S, N1
Paudel, YN1
K L, K1

Reviews

5 reviews available for metformin and Aura

ArticleYear
A review on role of metformin as a potential drug for epilepsy treatment and modulation of epileptogenesis.
    Seizure, 2022, Volume: 101

    Topics: AMP-Activated Protein Kinases; Anticonvulsants; Epilepsy; Humans; Metformin; TOR Serine-Threonine Ki

2022
Tuberous Sclerosis, Type II Diabetes Mellitus and the PI3K/AKT/mTOR Signaling Pathways-Case Report and Literature Review.
    Genes, 2023, 02-08, Volume: 14, Issue:2

    Topics: Adolescent; Adult; Diabetes Mellitus, Type 2; Epilepsy; Female; Humans; Infant; Metformin; Phosphati

2023
Beneficial Effects of Metformin on the Central Nervous System, with a Focus on Epilepsy and Lafora Disease.
    International journal of molecular sciences, 2021, May-19, Volume: 22, Issue:10

    Topics: Animals; Central Nervous System; Diabetes Mellitus, Type 2; Disease Models, Animal; Epilepsy; Humans

2021
The Effect of Metformin in Experimentally Induced Animal Models of Epileptic Seizure.
    Behavioural neurology, 2019, Volume: 2019

    Topics: Animals; Anticonvulsants; Behavior; Epilepsy; Humans; Metformin; Models, Animal; Seizures

2019
Envisioning the neuroprotective effect of Metformin in experimental epilepsy: A portrait of molecular crosstalk.
    Life sciences, 2019, Sep-15, Volume: 233

    Topics: Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; Epilepsy; Hypoglycemic Agents; Metformin

2019

Other Studies

4 other studies available for metformin and Aura

ArticleYear
Anticonvulsant Profile of Selected Medium-Chain Fatty Acids (MCFAs) Co-Administered with Metformin in Mice in Acute and Chronic Treatment.
    Molecules (Basel, Switzerland), 2023, Apr-29, Volume: 28, Issue:9

    Topics: AMP-Activated Protein Kinases; Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relat

2023
Metformin, valproic acid, and starvation induce seizures in a patient with partial SLC13A5 deficiency: a case of pharmaco-synergistic heterozygosity.
    Psychiatric genetics, 2021, 02-01, Volume: 31, Issue:1

    Topics: Adult; Amino Acid Substitution; Ammonia; Animals; Anticonvulsants; Autistic Disorder; Bipolar Disord

2021
Metformin Plus Caloric Restriction Show Anti-epileptic Effects Mediated by mTOR Pathway Inhibition.
    Cellular and molecular neurobiology, 2018, Volume: 38, Issue:7

    Topics: AMP-Activated Protein Kinases; Animals; Anticonvulsants; Caloric Restriction; Combined Modality Ther

2018
Effects of metformin on apoptosis and α-synuclein in a rat model of pentylenetetrazole-induced epilepsy.
    Canadian journal of physiology and pharmacology, 2019, Volume: 97, Issue:1

    Topics: alpha-Synuclein; Animals; Apoptosis; Convulsants; Epilepsy; Male; Metformin; Pentylenetetrazole; Rat

2019