Page last updated: 2024-10-30

metformin and Atrophy

metformin has been researched along with Atrophy in 5 studies

Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.

Atrophy: Decrease in the size of a cell, tissue, organ, or multiple organs, associated with a variety of pathological conditions such as abnormal cellular changes, ischemia, malnutrition, or hormonal changes.

Research Excerpts

ExcerptRelevanceReference
"Our findings revealed that metformin could induce endometrial atrophy in 21 out of 22 patients (95."5.19Antiproliferative effect of metformin on the endometrium--a clinical trial. ( Bidadi, S; Foroughi, M; Ghojazadeh, M; Melli, MS; Tabrizi, AD, 2014)
"Metformin (200mg/kg) was given at the time of reperfusion daily until sacrifice."1.40Metformin promotes focal angiogenesis and neurogenesis in mice following middle cerebral artery occlusion. ( Liu, Y; Tang, G; Wang, Y; Yang, GY; Zhang, Z, 2014)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (60.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
Antal, B1
McMahon, LP1
Sultan, SF1
Lithen, A1
Wexler, DJ1
Dickerson, B1
Ratai, EM1
Mujica-Parodi, LR1
Nabizadeh, F1
Kankam, SB1
Balabandian, M1
Hashemi, SM1
Sharifkazemi, H1
Rostami, MR1
Liu, Y1
Tang, G1
Zhang, Z1
Wang, Y1
Yang, GY1
Tabrizi, AD1
Melli, MS1
Foroughi, M1
Ghojazadeh, M1
Bidadi, S1
Liberati-Čizmek, AM1
Kruljac, I1
Bakula, M1

Reviews

1 review available for metformin and Atrophy

ArticleYear
Type 2 diabetes mellitus accelerates brain aging and cognitive decline: Complementary findings from UK Biobank and meta-analyses.
    eLife, 2022, 05-24, Volume: 11

    Topics: Aged; Aged, 80 and over; Aging; Atrophy; Biological Specimen Banks; Cognitive Dysfunction; Cross-Sec

2022

Trials

1 trial available for metformin and Atrophy

ArticleYear
Antiproliferative effect of metformin on the endometrium--a clinical trial.
    Asian Pacific journal of cancer prevention : APJCP, 2014, Volume: 15, Issue:23

    Topics: Adult; Antineoplastic Agents, Hormonal; Atrophy; Carcinoma, Endometrioid; Endometrial Hyperplasia; E

2014

Other Studies

3 other studies available for metformin and Atrophy

ArticleYear
Metformin use and brain atrophy in nondemented elderly individuals with diabetes.
    Experimental gerontology, 2022, Volume: 166

    Topics: Aged; Alzheimer Disease; Atrophy; Brain; Cognitive Dysfunction; Diabetes Mellitus; Hippocampus; Huma

2022
Metformin promotes focal angiogenesis and neurogenesis in mice following middle cerebral artery occlusion.
    Neuroscience letters, 2014, Sep-05, Volume: 579

    Topics: Animals; Atrophy; Brain; Cyclic AMP-Dependent Protein Kinases; Doublecortin Protein; Hypoglycemic Ag

2014
A 65-year-old female with poorly controlled type 2 diabetes mellitus.
    The Netherlands journal of medicine, 2015, Volume: 73, Issue:10

    Topics: Aged; Atrophy; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents;

2015