metformin has been researched along with Atrial Remodeling in 5 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Atrial Remodeling: Long-term changes in the electrophysiological parameters and/or anatomical structures of the HEART ATRIA that result from prolonged changes in atrial rate, often associated with ATRIAL FIBRILLATION or long periods of intense EXERCISE.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Moreover, compared to diabetic untreated and metformin-treated animals, those treated with PAP1 had the lowest risk of developing the life-threatening arrhythmia Torsade de Pointes under cardiac challenge." | 4.31 | Kv1.3 Channel Blockade Improves Inflammatory Profile, Reduces Cardiac Electrical Remodeling, and Prevents Arrhythmia in Type 2 Diabetic Rats. ( Alquiza, A; Casis, O; Echeazarra, L; Fernández-López, V; Gallego, M; Rodríguez-de-Yurre, A; Zayas-Arrabal, J, 2023) |
| "Laboratory studies suggest that metformin limits atherosclerosis." | 3.80 | The cardiovascular effects of metformin: lost in translation? ( Riksen, NP; Tack, CJ, 2014) |
| "Fibrosis was significantly less in treated mice atria." | 1.62 | Activation of AMP-Activated Protein Kinases Prevents Atrial Fibrillation. ( Dixit, G; Li, Z; Ozcan, C, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 4 (80.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zayas-Arrabal, J | 1 |
| Alquiza, A | 1 |
| Rodríguez-de-Yurre, A | 1 |
| Echeazarra, L | 1 |
| Fernández-López, V | 1 |
| Gallego, M | 1 |
| Casis, O | 1 |
| Liu, Y | 1 |
| Bai, F | 2 |
| Liu, N | 2 |
| Zhang, B | 2 |
| Qin, F | 2 |
| Tu, T | 2 |
| Li, B | 2 |
| Li, J | 2 |
| Ma, Y | 1 |
| Ouyang, F | 1 |
| Liu, Q | 2 |
| Po, SS | 1 |
| Sun, C | 1 |
| Xiao, Y | 1 |
| Zhou, S | 1 |
| Ozcan, C | 1 |
| Dixit, G | 1 |
| Li, Z | 1 |
| Riksen, NP | 1 |
| Tack, CJ | 1 |
5 other studies available for metformin and Atrial Remodeling
| Article | Year |
|---|---|
Kv1.3 Channel Blockade Improves Inflammatory Profile, Reduces Cardiac Electrical Remodeling, and Prevents Arrhythmia in Type 2 Diabetic Rats.
Topics: Animals; Arrhythmias, Cardiac; Atrial Remodeling; Cytokines; Diabetes Mellitus, Experimental; Diabet | 2023 |
Metformin improves lipid metabolism and reverses the Warburg effect in a canine model of chronic atrial fibrillation.
Topics: AMP-Activated Protein Kinases; Animals; Atrial Appendage; Atrial Fibrillation; Atrial Function, Left | 2020 |
Metformin regulates adiponectin signalling in epicardial adipose tissue and reduces atrial fibrillation vulnerability.
Topics: 3T3-L1 Cells; Adipocytes; Adiponectin; Adipose Tissue; Animals; Atrial Fibrillation; Atrial Remodeli | 2020 |
Activation of AMP-Activated Protein Kinases Prevents Atrial Fibrillation.
Topics: AMP-Activated Protein Kinases; Animals; Anti-Arrhythmia Agents; Aspirin; Atrial Fibrillation; Atrial | 2021 |
The cardiovascular effects of metformin: lost in translation?
Topics: Animals; Atherosclerosis; Atrial Remodeling; Carotid Intima-Media Thickness; Clinical Trials as Topi | 2014 |