metformin has been researched along with Astrocytosis in 3 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lafora disease is a fatal form of progressive myoclonic epilepsy caused by mutations in the EPM2A or NHLRC1/EPM2B genes that usually appears during adolescence." | 1.91 | Early Treatment with Metformin Improves Neurological Outcomes in Lafora Disease. ( Burgos, DF; Giráldez, BG; González-Fernández, J; Iglesias-Cabeza, N; Machío-Castello, M; Sánchez, MP; Sánchez-Martín, G; Serratosa, JM, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Burgos, DF | 1 |
| Machío-Castello, M | 1 |
| Iglesias-Cabeza, N | 1 |
| Giráldez, BG | 1 |
| González-Fernández, J | 1 |
| Sánchez-Martín, G | 1 |
| Sánchez, MP | 2 |
| Serratosa, JM | 2 |
| Grissi, M | 1 |
| Boudot, C | 1 |
| Assem, M | 1 |
| Candellier, A | 1 |
| Lando, M | 1 |
| Poirot-Leclercq, S | 1 |
| Boullier, A | 1 |
| Bennis, Y | 1 |
| Lenglet, G | 1 |
| Avondo, C | 1 |
| Lalau, JD | 1 |
| Choukroun, G | 1 |
| Massy, ZA | 1 |
| Kamel, S | 1 |
| Chillon, JM | 1 |
| Hénaut, L | 1 |
| Berthier, A | 1 |
| Payá, M | 1 |
| García-Cabrero, AM | 1 |
| Ballester, MI | 1 |
| Heredia, M | 1 |
| Sanz, P | 1 |
3 other studies available for metformin and Astrocytosis
| Article | Year |
|---|---|
Early Treatment with Metformin Improves Neurological Outcomes in Lafora Disease.
Topics: Animals; Follow-Up Studies; Gliosis; Lafora Disease; Metformin; Mice; Ubiquitin-Protein Ligases | 2023 |
Metformin prevents stroke damage in non-diabetic female mice with chronic kidney disease.
Topics: Adenylate Kinase; Animals; Apoptosis; Body Weight; Brain Infarction; Enzyme Activation; Female; Gene | 2021 |
Pharmacological Interventions to Ameliorate Neuropathological Symptoms in a Mouse Model of Lafora Disease.
Topics: Animals; Brain; Disease Models, Animal; Fluorescent Antibody Technique; Gliosis; Glucans; Hippocampu | 2016 |