Page last updated: 2024-10-30

metformin and Anesthesia

metformin has been researched along with Anesthesia in 9 studies

Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.

Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.

Research Excerpts

ExcerptRelevanceReference
"To determine whether a causal or coincidental relationship is indicated in the literature between metaformin and lactic acidosis and to recommend clinical guidelines for the withdrawal of metformin prior to surgery."8.82Metformin lactic acidosis and anaesthesia: myth or reality? ( De Kock, M; Vreven, R, 2005)
"To investigate the protective effects of metformin on the diabetic mice with cognitive impairment induced by the combination of streptozotocin (STZ) and isoflurane anesthesia."8.02Metformin improves cognitive impairment in diabetic mice induced by a combination of streptozotocin and isoflurane anesthesia. ( Li, P; Lv, Z; Zhang, J; Zhang, W; Zhao, L, 2021)
"To determine whether a causal or coincidental relationship is indicated in the literature between metaformin and lactic acidosis and to recommend clinical guidelines for the withdrawal of metformin prior to surgery."4.82Metformin lactic acidosis and anaesthesia: myth or reality? ( De Kock, M; Vreven, R, 2005)
"To investigate the protective effects of metformin on the diabetic mice with cognitive impairment induced by the combination of streptozotocin (STZ) and isoflurane anesthesia."4.02Metformin improves cognitive impairment in diabetic mice induced by a combination of streptozotocin and isoflurane anesthesia. ( Li, P; Lv, Z; Zhang, J; Zhang, W; Zhao, L, 2021)
"Metformin supplementation did not influence the induction time of propofol anesthesia in mice, while the dose of propofol was significantly decreased."3.91Metformin with propofol enhances the scavenging ability of free radicals and inhibits lipid peroxidation in mice. ( Chen, Y; Liu, NH; Zhang, XB; Zhu, L, 2019)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (66.67)29.6817
2010's2 (22.22)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Zhang, W1
Zhao, L1
Zhang, J1
Li, P1
Lv, Z1
Finley, J1
Liu, NH1
Zhu, L1
Zhang, XB1
Chen, Y1
Landgraf, R1
Nawroth, PP1
von Keinbaum, P1
Peters, J1
Ley, SC1
Preckel, B1
Schlack, W1
Vreven, R1
De Kock, M1
Chadwick, WA1
Roux, S1
van de Venter, M1
Louw, J1
Oelofsen, W1
Heikkinen, M1
Salmenperä, M1
Lepäntalo, A1
Lepäntalo, M1

Reviews

4 reviews available for metformin and Anesthesia

ArticleYear
[Perioperative metformin and lactacidosis].
    Der Anaesthesist, 2002, Volume: 51, Issue:10

    Topics: Acidosis, Lactic; Anesthesia; Animals; Diabetes Complications; Humans; Hypoglycemic Agents; Intraope

2002
[Perioperative treatment of patients with Diabetes mellitus].
    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 2005, Volume: 40, Issue:4

    Topics: Anesthesia; Blood Transfusion; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type

2005
Metformin lactic acidosis and anaesthesia: myth or reality?
    Acta anaesthesiologica Belgica, 2005, Volume: 56, Issue:3

    Topics: Acidosis, Lactic; Anesthesia; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Metformin

2005
Diabetes care for patients with peripheral arterial disease.
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2007, Volume: 33, Issue:5

    Topics: Anesthesia; Blood Pressure; Contrast Media; Diabetic Angiopathies; Diabetic Foot; Glycated Hemoglobi

2007

Other Studies

5 other studies available for metformin and Anesthesia

ArticleYear
Metformin improves cognitive impairment in diabetic mice induced by a combination of streptozotocin and isoflurane anesthesia.
    Bioengineered, 2021, Volume: 12, Issue:2

    Topics: Anesthesia; Animals; Cognitive Dysfunction; Diabetes Mellitus, Experimental; Disease Models, Animal;

2021
Cellular stress and AMPK links metformin and diverse compounds with accelerated emergence from anesthesia and potential recovery from disorders of consciousness.
    Medical hypotheses, 2019, Volume: 124

    Topics: AMP-Activated Protein Kinases; Anesthesia; Anesthesia Recovery Period; Anesthetics; Animals; Brain M

2019
Metformin with propofol enhances the scavenging ability of free radicals and inhibits lipid peroxidation in mice.
    European review for medical and pharmacological sciences, 2019, Volume: 23, Issue:11

    Topics: Anesthesia; Anesthetics, Intravenous; Animals; Drug Synergism; Free Radical Scavengers; Free Radical

2019
[Metformin and anesthesia].
    Der Anaesthesist, 2002, Volume: 51, Issue:6

    Topics: Acidosis, Lactic; Anesthesia; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Metformin

2002
Anti-diabetic effects of Sutherlandia frutescens in Wistar rats fed a diabetogenic diet.
    Journal of ethnopharmacology, 2007, Jan-03, Volume: 109, Issue:1

    Topics: Anesthesia; Animals; Blood Glucose; Body Weight; Diet; Dietary Fats; Glucose; Glycogen; Hyperinsulin

2007