metformin has been researched along with Anemia, Diamond-Blackfan in 1 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Anemia, Diamond-Blackfan: A rare congenital hypoplastic anemia that usually presents early in infancy. The disease is characterized by a moderate to severe macrocytic anemia, occasional neutropenia or thrombocytosis, a normocellular bone marrow with erythroid hypoplasia, and an increased risk of developing leukemia. (Curr Opin Hematol 2000 Mar;7(2):85-94)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metformin is a well-tolerated drug for type 2 diabetes with multiple cellular targets." | 1.56 | Metformin-induced suppression of Nemo-like kinase improves erythropoiesis in preclinical models of Diamond-Blackfan anemia through induction of miR-26a. ( Chen, J; Flygare, J; Glader, B; Kam, S; Kapur, S; Lin, S; Mercado, J; Narla, A; Perez, CA; Sakamoto, KM; Saxena, M; Serrano, M; Siva, K; Varetti, G; Wentworth, EP; Wilkes, MC, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wilkes, MC | 1 |
| Siva, K | 1 |
| Varetti, G | 1 |
| Mercado, J | 1 |
| Wentworth, EP | 1 |
| Perez, CA | 1 |
| Saxena, M | 1 |
| Kam, S | 1 |
| Kapur, S | 1 |
| Chen, J | 1 |
| Narla, A | 1 |
| Glader, B | 1 |
| Lin, S | 1 |
| Serrano, M | 1 |
| Flygare, J | 1 |
| Sakamoto, KM | 1 |
1 other study available for metformin and Anemia, Diamond-Blackfan
| Article | Year |
|---|---|
Metformin-induced suppression of Nemo-like kinase improves erythropoiesis in preclinical models of Diamond-Blackfan anemia through induction of miR-26a.
Topics: 3' Untranslated Regions; Anemia, Diamond-Blackfan; Animals; Cells, Cultured; Colony-Forming Units As | 2020 |