metformin has been researched along with Alveolar Bone Atrophy in 14 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to develop a chitosan-metformin based intrapocket dental film (CMIDF) for applications in the treatment of periodontitis and alveolar bone loss in an rat model of periodontitis." | 7.88 | Development and evaluation of novel biodegradable chitosan based metformin intrapocket dental film for the management of periodontitis and alveolar bone loss in a rat model. ( Karasik, D; Khajuria, DK; Patil, ON; Razdan, R, 2018) |
| "To evaluate the effects of metformin (Met) on inflammation, oxidative stress, and bone loss in a rat model of ligature-induced periodontitis." | 7.85 | Effects of metformin on inflammation, oxidative stress, and bone loss in a rat model of periodontitis. ( Araújo Júnior, RF; Araújo, AA; Araújo, LS; Brito, GAC; Guedes, PMM; Hiyari, S; Leitão, RFC; Medeiros, CACX; Pereira, ASBF; Pirih, FQ, 2017) |
| "In ligature-induced periodontitis, the metformin treatment of rats induced a significant reduction in alveolar bone loss compared to vehicle-treated rats." | 7.76 | The effect of metformin on alveolar bone in ligature-induced periodontitis in rats: a pilot study. ( Bak, EJ; Cha, JH; Choi, SH; Kim, M; Kim, S; Kim, SW; Park, HG; Yoo, YJ, 2010) |
| "This study evaluated the influence of type 2 diabetes mellitus on bone loss, bone repair and cytokine production in hyperglycemic rats, treated or not with metformin." | 5.56 | Impact of hyperglycemia and treatment with metformin on ligature-induced bone loss, bone repair and expression of bone metabolism transcription factors. ( Azarias, JS; Bastos, MF; Garcia, RP; Malta, FS; Miranda, TS; Ribeiro, GKDR; Shibli, JA, 2020) |
| "The aim of this study was to develop a chitosan-metformin based intrapocket dental film (CMIDF) for applications in the treatment of periodontitis and alveolar bone loss in an rat model of periodontitis." | 3.88 | Development and evaluation of novel biodegradable chitosan based metformin intrapocket dental film for the management of periodontitis and alveolar bone loss in a rat model. ( Karasik, D; Khajuria, DK; Patil, ON; Razdan, R, 2018) |
| "To evaluate the effects of metformin (Met) on inflammation, oxidative stress, and bone loss in a rat model of ligature-induced periodontitis." | 3.85 | Effects of metformin on inflammation, oxidative stress, and bone loss in a rat model of periodontitis. ( Araújo Júnior, RF; Araújo, AA; Araújo, LS; Brito, GAC; Guedes, PMM; Hiyari, S; Leitão, RFC; Medeiros, CACX; Pereira, ASBF; Pirih, FQ, 2017) |
| "In ligature-induced periodontitis, the metformin treatment of rats induced a significant reduction in alveolar bone loss compared to vehicle-treated rats." | 3.76 | The effect of metformin on alveolar bone in ligature-induced periodontitis in rats: a pilot study. ( Bak, EJ; Cha, JH; Choi, SH; Kim, M; Kim, S; Kim, SW; Park, HG; Yoo, YJ, 2010) |
| "This study evaluated the influence of type 2 diabetes mellitus on bone loss, bone repair and cytokine production in hyperglycemic rats, treated or not with metformin." | 1.56 | Impact of hyperglycemia and treatment with metformin on ligature-induced bone loss, bone repair and expression of bone metabolism transcription factors. ( Azarias, JS; Bastos, MF; Garcia, RP; Malta, FS; Miranda, TS; Ribeiro, GKDR; Shibli, JA, 2020) |
| "Felodipine was withdrawn and the diabetes was controlled before dental treatment was initiated." | 1.33 | Felodipine-influenced gingival enlargement in an uncontrolled type 2 diabetic patient. ( Fay, AA; Gapski, R; Satheesh, K, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 11 (78.57) | 24.3611 |
| 2020's | 2 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Ikhar, AS | 1 |
| Kolte, RA | 1 |
| Kolte, AP | 1 |
| Purohit, AR | 1 |
| Dahake, RN | 1 |
| Malta, FS | 1 |
| Garcia, RP | 1 |
| Azarias, JS | 1 |
| Ribeiro, GKDR | 1 |
| Miranda, TS | 1 |
| Shibli, JA | 1 |
| Bastos, MF | 1 |
| Araújo, AA | 1 |
| Pereira, ASBF | 1 |
| Medeiros, CACX | 1 |
| Brito, GAC | 1 |
| Leitão, RFC | 1 |
| Araújo, LS | 1 |
| Guedes, PMM | 1 |
| Hiyari, S | 1 |
| Pirih, FQ | 1 |
| Araújo Júnior, RF | 1 |
| Khajuria, DK | 1 |
| Patil, ON | 1 |
| Karasik, D | 1 |
| Razdan, R | 1 |
| Kurian, IG | 1 |
| Dileep, P | 1 |
| Ipshita, S | 1 |
| Pradeep, AR | 5 |
| Nagpal, K | 2 |
| Karvekar, S | 2 |
| Patnaik, K | 2 |
| Naik, SB | 4 |
| Guruprasad, CN | 1 |
| Ramamurthy, BL | 1 |
| Suke, D | 1 |
| Singh, P | 1 |
| Raju, A | 1 |
| Malhotra, A | 1 |
| Bak, EJ | 1 |
| Park, HG | 1 |
| Kim, M | 1 |
| Kim, SW | 1 |
| Kim, S | 1 |
| Choi, SH | 1 |
| Cha, JH | 1 |
| Yoo, YJ | 1 |
| Han, B | 1 |
| You, L | 1 |
| Rao, NS | 2 |
| Kumari, M | 2 |
| Liu, L | 1 |
| Zhang, C | 1 |
| Hu, Y | 1 |
| Peng, B | 1 |
| Fay, AA | 1 |
| Satheesh, K | 1 |
| Gapski, R | 1 |
1 review available for metformin and Alveolar Bone Atrophy
| Article | Year |
|---|---|
Efficacy of platelet rich fibrin with and without metformin in the treatment of periodontal osseous defects: a systematic review and meta-analysis.
Topics: Alveolar Bone Loss; Humans; Inflammatory Bowel Diseases; Metformin; Periodontal Attachment Loss; Pla | 2023 |
4 trials available for metformin and Alveolar Bone Atrophy
| Article | Year |
|---|---|
Platelet-rich fibrin with 1% metformin for the treatment of intrabony defects in chronic periodontitis: a randomized controlled clinical trial.
Topics: Adult; Alveolar Bone Loss; Blood Platelets; Chronic Periodontitis; Debridement; Dental Plaque Index; | 2015 |
Efficacy of locally-delivered 1% metformin gel in the treatment of intrabony defects in patients with chronic periodontitis: a randomized, controlled clinical trial.
Topics: Adult; Alveolar Bone Loss; Chronic Periodontitis; Combined Modality Therapy; Dental Scaling; Female; | 2016 |
Efficacy of varying concentrations of subgingivally delivered metformin in the treatment of chronic periodontitis: a randomized controlled clinical trial.
Topics: Administration, Topical; Adult; Alveolar Bone Loss; Chromatography, High Pressure Liquid; Chronic Pe | 2013 |
Locally delivered 1% metformin gel in the treatment of smokers with chronic periodontitis: a randomized controlled clinical trial.
Topics: Administration, Topical; Adult; Alveolar Bone Loss; Bone Density Conservation Agents; Chronic Period | 2013 |
9 other studies available for metformin and Alveolar Bone Atrophy
| Article | Year |
|---|---|
Impact of hyperglycemia and treatment with metformin on ligature-induced bone loss, bone repair and expression of bone metabolism transcription factors.
Topics: Alveolar Bone Loss; Alveolar Process; Animals; Bone Regeneration; Cell Differentiation; Cytokines; D | 2020 |
Effects of metformin on inflammation, oxidative stress, and bone loss in a rat model of periodontitis.
Topics: Alveolar Bone Loss; Animals; Disease Models, Animal; Gingiva; Glutathione Peroxidase; Glutathione Pe | 2017 |
Development and evaluation of novel biodegradable chitosan based metformin intrapocket dental film for the management of periodontitis and alveolar bone loss in a rat model.
Topics: Alveolar Bone Loss; Animals; Anti-Bacterial Agents; Chitosan; Disease Models, Animal; Drug Implants; | 2018 |
Comparative evaluation of subgingivally-delivered 1% metformin and Aloe vera gel in the treatment of intrabony defects in chronic periodontitis patients: A randomized, controlled clinical trial.
Topics: Adult; Alveolar Bone Loss; Chronic Periodontitis; Combined Modality Therapy; Dental Scaling; Female; | 2018 |
Letters to the Editor: Re: Platelet-Rich Fibrin With 1% Metformin for the Treatment of Intrabony Defects in Chronic Periodontitis: A Randomized Controlled Clinical Trial.
Topics: Alveolar Bone Loss; Chronic Periodontitis; Fibrin; Humans; Metformin; Periodontal Attachment Loss; P | 2016 |
The effect of metformin on alveolar bone in ligature-induced periodontitis in rats: a pilot study.
Topics: 3T3 Cells; Adipocytes; Alveolar Bone Loss; Animals; Cell Differentiation; Hypoglycemic Agents; Injec | 2010 |
[Effect of initial periodontal therapy on diabetic patients with chronic periodontitis].
Topics: Adult; Alveolar Bone Loss; Blood Glucose; Chronic Periodontitis; Dental Scaling; Diabetes Mellitus, | 2010 |
Protective effect of metformin on periapical lesions in rats by decreasing the ratio of receptor activator of nuclear factor kappa B ligand/osteoprotegerin.
Topics: Alveolar Bone Loss; Animals; Anti-Inflammatory Agents; Bone Remodeling; Injections, Intramuscular; M | 2012 |
Felodipine-influenced gingival enlargement in an uncontrolled type 2 diabetic patient.
Topics: Alveolar Bone Loss; Anti-Bacterial Agents; Anticholesteremic Agents; Calcium Channel Blockers; Denta | 2005 |