Page last updated: 2024-10-30

metformin and Alopecia

metformin has been researched along with Alopecia in 9 studies

Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.

Alopecia: Absence of hair from areas where it is normally present.

Research Excerpts

ExcerptRelevanceReference
"Twelve-month metformin treatment reduced fat content, waist circumference, glycated hemoglobin, glucose and triglycerides, as well as improved insulin sensitivity."8.12Impaired metabolic effects of metformin in men with early-onset androgenic alopecia. ( Kowalcze, K; Krysiak, R; Okopień, B, 2022)
"Metformin treatment may protect men with early-onset androgenic alopecia against the development of gonadotroph hyperplasia and/or focal testicular changes."5.72Pituitary Effects of Metformin in Men With Early-Onset Androgenic Alopecia. ( Kowalcze, K; Krysiak, R; Okopień, B, 2022)
"Twelve-month metformin treatment reduced fat content, waist circumference, glycated hemoglobin, glucose and triglycerides, as well as improved insulin sensitivity."4.12Impaired metabolic effects of metformin in men with early-onset androgenic alopecia. ( Kowalcze, K; Krysiak, R; Okopień, B, 2022)
"Metformin treatment may protect men with early-onset androgenic alopecia against the development of gonadotroph hyperplasia and/or focal testicular changes."1.72Pituitary Effects of Metformin in Men With Early-Onset Androgenic Alopecia. ( Kowalcze, K; Krysiak, R; Okopień, B, 2022)
"Hair loss or alopecia affects millions worldwide, but methods that can be used to regrow hair are lacking."1.51Stimulation of Hair Growth by Small Molecules that Activate Autophagy. ( Chai, M; Chu, J; Crooks, GM; de Barros, SC; Doan, NB; Fu, X; Herschman, H; Huang, J; Huang, W; Jiang, M; Jiao, J; Reue, K; Vergnes, L, 2019)
"We report a 69-year-old man with type 2 diabetes that developed sudden loss of eyebrows and eyelashes about 4 months after the beginning of Janumet®."1.46Loss of Eyebrows and Eyelashes During Concomitant Treatment with Sitagliptin and Metformin. ( Arturi, F; Gallelli, L; Palleria, C; Ruffo, M; Serra, R; Succurro, E, 2017)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (11.11)29.6817
2010's5 (55.56)24.3611
2020's3 (33.33)2.80

Authors

AuthorsStudies
Krysiak, R2
Kowalcze, K2
Okopień, B2
Torres-Zegarra, C1
Sundararajan, D1
Benson, J1
Seagle, H1
Witten, M1
Walders-Abramson, N1
Simon, SL1
Huguelet, P1
Nokoff, NJ1
Cree-Green, M1
Chai, M1
Jiang, M1
Vergnes, L1
Fu, X1
de Barros, SC1
Doan, NB1
Huang, W1
Chu, J1
Jiao, J1
Herschman, H1
Crooks, GM1
Reue, K1
Huang, J1
Buzney, E1
Sheu, J1
Buzney, C1
Reynolds, RV1
Goodman, NF1
Cobin, RH1
Futterweit, W1
Glueck, JS1
Legro, RS1
Carmina, E1
Succurro, E1
Palleria, C1
Ruffo, M1
Serra, R1
Arturi, F1
Gallelli, L1
Langmár, Z1
Jothilakshmi, PK1
Watson, AJ1
Jude, E1

Reviews

1 review available for metformin and Alopecia

ArticleYear
Polycystic ovary syndrome: a review for dermatologists: Part II. Treatment.
    Journal of the American Academy of Dermatology, 2014, Volume: 71, Issue:5

    Topics: 5-alpha Reductase Inhibitors; Acne Vulgaris; Alopecia; Androgen Antagonists; Contraceptives, Oral, C

2014

Other Studies

8 other studies available for metformin and Alopecia

ArticleYear
Impaired metabolic effects of metformin in men with early-onset androgenic alopecia.
    Pharmacological reports : PR, 2022, Volume: 74, Issue:1

    Topics: Alopecia; Biological Availability; Blood Glucose; Diabetes Mellitus, Type 2; Drug Monitoring; Humans

2022
Pituitary Effects of Metformin in Men With Early-Onset Androgenic Alopecia.
    Journal of clinical pharmacology, 2022, Volume: 62, Issue:11

    Topics: Adrenocorticotropic Hormone; Alopecia; Androgens; Dehydroepiandrosterone Sulfate; Follicle Stimulati

2022
Care for Adolescents With Polycystic Ovary Syndrome: Development and Prescribing Patterns of a Multidisciplinary Clinic.
    Journal of pediatric and adolescent gynecology, 2021, Volume: 34, Issue:5

    Topics: Adolescent; Adult; Alopecia; Child; Female; Hirsutism; Humans; Metformin; Polycystic Ovary Syndrome;

2021
Stimulation of Hair Growth by Small Molecules that Activate Autophagy.
    Cell reports, 2019, 06-18, Volume: 27, Issue:12

    Topics: Aging; Allyl Compounds; Alopecia; AMP-Activated Protein Kinases; Animals; Autophagy; Butyrates; Cell

2019
AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS, AMERICAN COLLEGE OF ENDOCRINOLOGY, AND ANDROGEN EXCESS AND PCOS SOCIETY DISEASE STATE CLINICAL REVIEW: GUIDE TO THE BEST PRACTICES IN THE EVALUATION AND TREATMENT OF POLYCYSTIC OVARY SYNDROME--PART 1.
    Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 2015, Volume: 21, Issue:11

    Topics: Adolescent; Alopecia; Androgen Antagonists; Androgens; Anovulation; Diagnostic Techniques, Endocrine

2015
Loss of Eyebrows and Eyelashes During Concomitant Treatment with Sitagliptin and Metformin.
    Current drug safety, 2017, Volume: 12, Issue:1

    Topics: Aged; Alopecia; Diabetes Mellitus, Type 2; Eyebrows; Eyelashes; Follow-Up Studies; Humans; Hypoglyce

2017
[Diagnosis and treatment of polycystic ovary syndrome].
    Orvosi hetilap, 2010, Apr-04, Volume: 151, Issue:14

    Topics: Acne Vulgaris; Alopecia; Amenorrhea; Androgens; Clomiphene; Diabetes Complications; Diagnosis, Diffe

2010
Acute alopecia due to metformin treatment for polycystic ovarian syndrome.
    Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 2006, Volume: 26, Issue:6

    Topics: Adult; Alopecia; Female; Humans; Hypoglycemic Agents; Metformin; Polycystic Ovary Syndrome

2006