metformin has been researched along with Alcoholism in 9 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Alcoholism: A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with metformin is occasionally associated with the development of severe lactic acidosis." | 3.69 | Contraindications to metformin therapy in patients with NIDDM. ( Bosman, D; Krentz, AJ; Sulkin, TV, 1997) |
| "The pooled HR of prostate cancer for metformin therapy was 0." | 2.66 | Effect of metformin on the risk of prostate cancer in patients with type 2 diabetes by considering different confounding factors: a meta-analysis of observational studies. ( Bi, Y; Chen, T; Liu, X; Sun, Y; Tang, J; Wang, Y; Yan, P; Zhang, ZJ; Zhou, W, 2020) |
| "The metformin intoxication was confirmed to be intentional in 23% (n = 5) of the single intoxications." | 1.51 | Metformin - Postmortem fatal and non-fatal reference concentrations in femoral blood and risk factors associated with fatal intoxications. ( Ahlner, J; Druid, H; Jönsson, AK; Östgren, CJ; Walz, L, 2019) |
| "Metformin-treated patients, especially elderly ones, are at a risk of sudden deterioration of renal function, which in turn may increase the risk of lactic acidosis." | 1.39 | Lactic acidosis in patients with diabetes. ( Karnafel, W; Krzymień, J, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 2 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| Walz, L | 1 |
| Jönsson, AK | 1 |
| Ahlner, J | 1 |
| Östgren, CJ | 1 |
| Druid, H | 1 |
| Serra, MC | 1 |
| Kancherla, V | 1 |
| Khakharia, A | 1 |
| Allen, LL | 1 |
| Phillips, LS | 1 |
| Rhee, MK | 1 |
| Wilson, PWF | 1 |
| Vaughan, CP | 1 |
| Wang, Y | 1 |
| Liu, X | 1 |
| Yan, P | 1 |
| Tang, J | 1 |
| Chen, T | 1 |
| Sun, Y | 1 |
| Zhou, W | 1 |
| Bi, Y | 1 |
| Zhang, ZJ | 1 |
| Li, X | 1 |
| Jiao, Y | 1 |
| Xing, Y | 1 |
| Gao, P | 1 |
| Krzymień, J | 1 |
| Karnafel, W | 1 |
| Bhasin, DK | 1 |
| Sidhu, RS | 1 |
| Bhansali, A | 1 |
| Nagi, B | 1 |
| Nightingale, SL | 1 |
| Sulkin, TV | 1 |
| Bosman, D | 1 |
| Krentz, AJ | 1 |
| Debry, G | 1 |
| Laurent, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Study of Metformin Overdose in Adult Patients Treated at the University Hospital of Nancy: Single-center Descriptive Retrospective Observational Study[NCT04762966] | 50 participants (Anticipated) | Observational | 2021-03-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for metformin and Alcoholism
| Article | Year |
|---|---|
Effect of metformin on the risk of prostate cancer in patients with type 2 diabetes by considering different confounding factors: a meta-analysis of observational studies.
Topics: Alcoholism; Case-Control Studies; Confounding Factors, Epidemiologic; Diabetes Mellitus, Type 2; Gly | 2020 |
Diabetes Mellitus and Risk of Hepatic Fibrosis/Cirrhosis.
Topics: Alcoholism; Diabetes Complications; Diabetes Mellitus; Glucose; Hepacivirus; Hepatitis B; Hepatitis | 2019 |
7 other studies available for metformin and Alcoholism
| Article | Year |
|---|---|
Metformin - Postmortem fatal and non-fatal reference concentrations in femoral blood and risk factors associated with fatal intoxications.
Topics: Accidents; Adult; Aged; Aged, 80 and over; Alcoholism; Cardiovascular Diseases; Case-Control Studies | 2019 |
Long-term metformin treatment and risk of peripheral neuropathy in older Veterans.
Topics: Aged; Alcoholism; Body Mass Index; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Female; Humans; | 2020 |
Lactic acidosis in patients with diabetes.
Topics: Acidosis, Lactic; Adult; Aged; Aged, 80 and over; Alcohol Drinking; Alcoholism; Diabetes Mellitus, T | 2013 |
Diabetic ketoacidosis in a patient with chronic calcific pancreatitis after minor papilla stent insertion.
Topics: Alcoholism; Calcinosis; Cholangiopancreatography, Endoscopic Retrograde; Chronic Disease; Diabetic K | 2004 |
From the Food and Drug Administration.
Topics: Alcoholism; Diabetes Mellitus, Type 2; Drug Approval; Enzyme-Linked Immunosorbent Assay; HIV Antibod | 1995 |
Contraindications to metformin therapy in patients with NIDDM.
Topics: Acidosis, Lactic; Alcoholism; Contraindications; Diabetes Mellitus, Type 2; Diabetic Ketoacidosis; D | 1997 |
[Lactic acidosis and sugar diabetics].
Topics: Alcoholism; Diabetic Ketoacidosis; Humans; Hypoxia; Lactates; Metformin; Phenformin; Starvation | 1970 |