Page last updated: 2024-10-30

metformin and Aggression

metformin has been researched along with Aggression in 5 studies

Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.

Aggression: Behavior which may be manifested by destructive and attacking action which is verbal or physical, by covert attitudes of hostility or by obstructionism.

Research Excerpts

ExcerptRelevanceReference
" We present a case of psychosis associated with the menstrual cycle in a patient with polycystic ovary syndrome, a disorder typically characterized by anovulatory cycles, in whom the restoration of normal menstruation with use of metformine led to significant improvement of psychotic symptoms."7.74Metformine for psychosis associated with the menstrual cycle in a patient with polycystic ovary syndrome. ( Andreou, C; Karavatos, A; Syngelakis, M, 2008)
"The purpose of this manuscript is to review the evidence generated by clinical trials of pharmaceuticals in autism spectrum disorder (ASD), describe challenges in the conduct of such trials, and discuss future directions RECENT FINDINGS: Clinical trials in ASD have produced several compounds to adequately support the pharmacological treatment of associated symptom domains: attention deficit hyperactivity disorder (methylphenidate, atomoxetine, and alpha agonists), irritability/aggression (risperidone and aripiprazole), sleep (melatonin), and weight gain associated with atypical antipsychotic use (metformin)."4.98Clinical trials in autism spectrum disorder: evidence, challenges and future directions. ( Anagnostou, E, 2018)
" We present a case of psychosis associated with the menstrual cycle in a patient with polycystic ovary syndrome, a disorder typically characterized by anovulatory cycles, in whom the restoration of normal menstruation with use of metformine led to significant improvement of psychotic symptoms."3.74Metformine for psychosis associated with the menstrual cycle in a patient with polycystic ovary syndrome. ( Andreou, C; Karavatos, A; Syngelakis, M, 2008)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's3 (60.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Nagy, LR1
Rice, T1
Coffey, BJ2
Anagnostou, E1
MacLaren, RD1
Wisniewski, K1
MacLaren, C1
Salau, M1
Adam, B1
Andreou, C1
Syngelakis, M1
Karavatos, A1

Reviews

1 review available for metformin and Aggression

ArticleYear
Clinical trials in autism spectrum disorder: evidence, challenges and future directions.
    Current opinion in neurology, 2018, Volume: 31, Issue:2

    Topics: Adrenergic alpha-Agonists; Adrenergic Uptake Inhibitors; Aggression; Antipsychotic Agents; Aripipraz

2018

Other Studies

4 other studies available for metformin and Aggression

ArticleYear
Combined Topiramate and Metformin Pharmacotherapy for Second-Generation Antipsychotic-Induced Weight Gain in Pediatric Bipolar Disorder and Aggression.
    Journal of child and adolescent psychopharmacology, 2022, Volume: 32, Issue:1

    Topics: Aggression; Antipsychotic Agents; Bipolar Disorder; Child; Humans; Metformin; Topiramate; Weight Gai

2022
Environmental concentrations of metformin exposure affect aggressive behavior in the Siamese fighting fish, Betta splendens.
    PloS one, 2018, Volume: 13, Issue:5

    Topics: Aggression; Analysis of Variance; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Fishe

2018
Metformin in an Adolescent with Significant Weight Gain.
    Journal of child and adolescent psychopharmacology, 2015, Volume: 25, Issue:7

    Topics: Adolescent; Aggression; Antipsychotic Agents; Autism Spectrum Disorder; Humans; Hypoglycemic Agents;

2015
Metformine for psychosis associated with the menstrual cycle in a patient with polycystic ovary syndrome.
    Archives of women's mental health, 2008, Volume: 11, Issue:5-6

    Topics: Aggression; Female; Humans; Hypoglycemic Agents; Menstruation; Metformin; Polycystic Ovary Syndrome;

2008