metformin has been researched along with Adrenocortical Carcinoma in 2 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Adrenocortical Carcinoma: A malignant neoplasm of the ADRENAL CORTEX. Adrenocortical carcinomas are unencapsulated anaplastic (ANAPLASIA) masses sometimes exceeding 20 cm or 200 g. They are more likely to be functional than nonfunctional, and produce ADRENAL CORTEX HORMONES that may result in hypercortisolism (CUSHING SYNDROME); HYPERALDOSTERONISM; and/or VIRILISM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metformin has been proposed as a novel anti-cancer drug for adrenocortical carcinoma (ACC) based upon Poli's recent preclinical studies that 1." | 7.85 | Metformin and Melatonin in Adrenocortical Carcinoma: Morphoproteomics and Biomedical Analytics Provide Proof of Concept in a Case Study. ( Brown, RE; Buryanek, J; McGuire, MF, 2017) |
| "Metformin has been proposed as a novel anti-cancer drug for adrenocortical carcinoma (ACC) based upon Poli's recent preclinical studies that 1." | 3.85 | Metformin and Melatonin in Adrenocortical Carcinoma: Morphoproteomics and Biomedical Analytics Provide Proof of Concept in a Case Study. ( Brown, RE; Buryanek, J; McGuire, MF, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brown, RE | 1 |
| Buryanek, J | 1 |
| McGuire, MF | 1 |
| Poli, G | 1 |
| Cantini, G | 1 |
| Armignacco, R | 1 |
| Fucci, R | 1 |
| Santi, R | 1 |
| Canu, L | 1 |
| Nesi, G | 1 |
| Mannelli, M | 1 |
| Luconi, M | 1 |
2 other studies available for metformin and Adrenocortical Carcinoma
| Article | Year |
|---|---|
Metformin and Melatonin in Adrenocortical Carcinoma: Morphoproteomics and Biomedical Analytics Provide Proof of Concept in a Case Study.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Adult; Antioxidants; Biomarkers, Tumor; Drug The | 2017 |
Metformin as a new anti-cancer drug in adrenocortical carcinoma.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Animals; Antineoplastic Agents; Apoptosis; Caspa | 2016 |