metformin has been researched along with Adenoma, beta-Cell in 3 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Since improvement of β-cell viability is a promising anti-diabetic strategy, the protective effect of metformin, a known insulin sensitizer was studied in rat insulinoma cells." | 7.80 | Metformin attenuates palmitate-induced endoplasmic reticulum stress, serine phosphorylation of IRS-1 and apoptosis in rat insulinoma cells. ( Csala, M; Kéri, G; Kokas, M; Mandl, J; Simon-Szabó, L, 2014) |
| " Since improvement of β-cell viability is a promising anti-diabetic strategy, the protective effect of metformin, a known insulin sensitizer was studied in rat insulinoma cells." | 3.80 | Metformin attenuates palmitate-induced endoplasmic reticulum stress, serine phosphorylation of IRS-1 and apoptosis in rat insulinoma cells. ( Csala, M; Kéri, G; Kokas, M; Mandl, J; Simon-Szabó, L, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hamano, K | 1 |
| Akita, K | 1 |
| Takeuchi, Y | 1 |
| Suwa, T | 1 |
| Takeda, J | 1 |
| Dodo, S | 1 |
| Simon-Szabó, L | 1 |
| Kokas, M | 1 |
| Mandl, J | 1 |
| Kéri, G | 1 |
| Csala, M | 1 |
| Langelueddecke, C | 1 |
| Jakab, M | 1 |
| Ketterl, N | 1 |
| Lehner, L | 1 |
| Hufnagl, C | 1 |
| Schmidt, S | 1 |
| Geibel, JP | 1 |
| Fuerst, J | 1 |
| Ritter, M | 1 |
3 other studies available for metformin and Adenoma, beta-Cell
| Article | Year |
|---|---|
Glucose-responsive Insulinoma with Insulin Hypersecretion Suppressed by Metformin.
Topics: Glucose Tolerance Test; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Insulinoma; Male; Metfor | 2019 |
Metformin attenuates palmitate-induced endoplasmic reticulum stress, serine phosphorylation of IRS-1 and apoptosis in rat insulinoma cells.
Topics: Animals; Apoptosis; Caspase 3; Cell Line, Tumor; Endoplasmic Reticulum Stress; Eukaryotic Initiation | 2014 |
Effect of the AMP-kinase modulators AICAR, metformin and compound C on insulin secretion of INS-1E rat insulinoma cells under standard cell culture conditions.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Apoptosis; Calcium; Cell Line, T | 2012 |