metformin has been researched along with Acute Disease in 31 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Acute Disease: Disease having a short and relatively severe course.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In people with metformin-treated diabetes, to evaluate the risk of acute pancreatitis, pancreatic cancer and other diseases of the pancreas post second-line anti-hyperglycaemic agent initiation." | 7.91 | Treatment with incretins does not increase the risk of pancreatic diseases compared to older anti-hyperglycaemic drugs, when added to metformin: real world evidence in people with Type 2 diabetes. ( Atherton, J; Green, JB; Montvida, O; Paul, SK, 2019) |
| " It compared metformin and other hypoglycaemic medication use in diabetic patients with uncomplicated diverticulosis to those with acute diverticulitis." | 7.85 | Metformin use in diabetics with diverticular disease is associated with reduced incidence of diverticulitis. ( Croagh, D; Evans, JA; Freckelton, J; Moore, GT, 2017) |
| " All-cause mortality was considered as the primary endpoint and the effect of metformin therapy across the most representative subgroups in heart failure as a secondary endpoint." | 7.85 | Metformin and risk of long-term mortality following an admission for acute heart failure. ( Bertomeu, V; Fabregat-Andrés, Ó; Fácila, L; García-Blas, S; Miñana, G; Morell, S; Navarro, JP; Núñez, J; Sanchis, J; Valero, E, 2017) |
| "Accumulating evidence suggests that chronic metformin preconditioning offers potent neuroprotective effects against ischemic stroke." | 7.81 | Chronic Metformin Preconditioning Provides Neuroprotection via Suppression of NF-κB-Mediated Inflammatory Pathway in Rats with Permanent Cerebral Ischemia. ( Cao, L; Ding, ZZ; Jiang, T; Tan, L; Tan, MS; Wang, HF; Yu, JT; Zhang, QQ; Zhu, XC, 2015) |
| "Treatment with metformin also alleviated the histological abnormalities in the heart, suppressed the upregulation of myeloperoxidase (MPO), decreased the elevation of creatinine kinase-myocardial band (CK-MB) and brain natriuretic peptide (BNP)." | 5.46 | Metformin attenuated endotoxin-induced acute myocarditis via activating AMPK. ( Dai, J; Ge, P; Huang, W; Lei, H; Lin, L; Liu, G; Luo, F; Wu, K; Zhang, L, 2017) |
| "Byetta was withdrawn, the patient was treated for acute pancreatitis and the symptoms subsided." | 5.35 | Exenatide and acute pancreatitis. ( Basha, S; Jain, R; Ramachandran, A; Shetty, S; Tripathy, NR, 2008) |
| "Metformin is a biguanide commonly used in type 2 diabetes and considered to be a safe drug with minimal side effects." | 5.32 | Metformin induced acute pancreatitis precipitated by renal failure. ( Mallick, S, 2004) |
| "We performed a systematic search on PubMed, applying the following search terms: "acute metabolic acidosis," "lactic acidosis," "metformin" AND "acidosis," "unbalanced solutions" AND "acidosis," "bicarbonate" AND "acidosis" AND "outcome," "acute metabolic acidosis" AND "management," and "acute metabolic acidosis" AND "renal replacement therapy (RRT)/dialysis." | 5.05 | Etiology and Management of Acute Metabolic Acidosis: An Update. ( Matyukhin, I; Patschan, D; Patschan, S; Ritter, O, 2020) |
| " On the other hand, treatment of obese patients with metformin significantly reduced the incidence of myocardial infarction and of mortality diabetes related." | 4.80 | [Should the occurrence of a first coronary event change the management of diabetes?]. ( Dubois-Laforgue, D; Timsit, J, 2000) |
| "In people with metformin-treated diabetes, to evaluate the risk of acute pancreatitis, pancreatic cancer and other diseases of the pancreas post second-line anti-hyperglycaemic agent initiation." | 3.91 | Treatment with incretins does not increase the risk of pancreatic diseases compared to older anti-hyperglycaemic drugs, when added to metformin: real world evidence in people with Type 2 diabetes. ( Atherton, J; Green, JB; Montvida, O; Paul, SK, 2019) |
| " It compared metformin and other hypoglycaemic medication use in diabetic patients with uncomplicated diverticulosis to those with acute diverticulitis." | 3.85 | Metformin use in diabetics with diverticular disease is associated with reduced incidence of diverticulitis. ( Croagh, D; Evans, JA; Freckelton, J; Moore, GT, 2017) |
| " All-cause mortality was considered as the primary endpoint and the effect of metformin therapy across the most representative subgroups in heart failure as a secondary endpoint." | 3.85 | Metformin and risk of long-term mortality following an admission for acute heart failure. ( Bertomeu, V; Fabregat-Andrés, Ó; Fácila, L; García-Blas, S; Miñana, G; Morell, S; Navarro, JP; Núñez, J; Sanchis, J; Valero, E, 2017) |
| "Accumulating evidence suggests that chronic metformin preconditioning offers potent neuroprotective effects against ischemic stroke." | 3.81 | Chronic Metformin Preconditioning Provides Neuroprotection via Suppression of NF-κB-Mediated Inflammatory Pathway in Rats with Permanent Cerebral Ischemia. ( Cao, L; Ding, ZZ; Jiang, T; Tan, L; Tan, MS; Wang, HF; Yu, JT; Zhang, QQ; Zhu, XC, 2015) |
| "Although metformin-associated lactic acidosis is well described, there is less information on metformin overdose and whether it is of similar severity." | 3.81 | Hyperlactataemia and clinical severity of acute metformin overdose. ( Isbister, GK; McNamara, K, 2015) |
| " The overall frequency of adverse events was similar among the groups." | 2.84 | Randomized, double-blind, phase III study to evaluate the efficacy and safety of once-daily treatment with alogliptin and metformin hydrochloride in Japanese patients with type 2 diabetes. ( Kaku, K; Katou, M; Kinugawa, Y; Nishiyama, Y; Sumino, S, 2017) |
| "Troglitazone treatment of type 2 diabetic patients diminishes sCD40L levels, suggesting a novel antiinflammatory mechanism for limiting diabetes-associated arterial disease." | 2.71 | Elevated plasma levels of the atherogenic mediator soluble CD40 ligand in diabetic patients: a novel target of thiazolidinediones. ( Bernal, MR; Calle-Pascual, AL; Fernández-Cruz, A; Goldfine, A; Horton, E; Jarolim, P; Libby, P; Nuzzo, R; Schönbeck, U; Varo, JJ; Varo, N; Veves, A; Vicent, D, 2003) |
| "Metformin is known to cause potentially fatal metabolic acidosis with an increased lactate level in both overdose and therapeutic use." | 2.45 | Acute metformin overdose: examining serum pH, lactate level, and metformin concentrations in survivors versus nonsurvivors: a systematic review of the literature. ( Abramson, J; Dell'Aglio, DM; Kazzi, Z; Morgan, BW; Perino, LJ; Schwartz, MD, 2009) |
| "Metformin treatment reduced liver injury caused by bile acid, and it suppressed ER stress, inflammation, chemokine expression, and neutrophil infiltration." | 1.56 | Metformin ameliorates bile duct ligation-induced acute hepatic injury via regulation of ER stress. ( Cho, DH; Han, JH; Kim, S; Lee, CH; Lee, H; Nam, DH; Woo, CH, 2020) |
| "Metformin has unexpected beneficial effects other than glucose-lowering effects." | 1.48 | Metformin protects against intestinal barrier dysfunction via AMPKα1-dependent inhibition of JNK signalling activation. ( Chen, Y; Deng, J; Lai, X; Li, J; Lin, Q; Liu, L; Zeng, L, 2018) |
| "Metformin has antineoplastic and cancer protective effects in vitro, sensitizing leukemia cells to chemotherapeutic agents, inducing apoptosis and cell cycle arrest." | 1.48 | [Effect of metformin added to chemotherapy on the survival of patients with acute lymphoblastic leukemia]. ( Centeno Cruz, F; Ceron Maldonado, R; Collazo Jaloma, J; Kassack Ipiña, JJ; Martínez Tovar, A; Miranda Peralta, E; Olarte Carrillo, I; Ramos Peñafiel, C; Rozen Fuller, E, 2018) |
| "Treatment with metformin also alleviated the histological abnormalities in the heart, suppressed the upregulation of myeloperoxidase (MPO), decreased the elevation of creatinine kinase-myocardial band (CK-MB) and brain natriuretic peptide (BNP)." | 1.46 | Metformin attenuated endotoxin-induced acute myocarditis via activating AMPK. ( Dai, J; Ge, P; Huang, W; Lei, H; Lin, L; Liu, G; Luo, F; Wu, K; Zhang, L, 2017) |
| "To assess the risk of acute pancreatitis during treatment with glucagon-like peptide 1 receptor agonist dulaglutide, placebo, and active comparators across phase 2/3 dulaglutide trials." | 1.46 | Assessment of Pancreas Safety in the Development Program of Once-Weekly GLP-1 Receptor Agonist Dulaglutide. ( Anglin, G; Barkin, JS; Frossard, JL; Harper, KD; Hensley, IE; Milicevic, Z; Nauck, MA, 2017) |
| "Byetta was withdrawn, the patient was treated for acute pancreatitis and the symptoms subsided." | 1.35 | Exenatide and acute pancreatitis. ( Basha, S; Jain, R; Ramachandran, A; Shetty, S; Tripathy, NR, 2008) |
| "Acute liver failure was defined as acute liver disease and (1) hepatic encephalopathy, (2) prothrombin time prolongation greater than 3 seconds or international normalized ratio greater than 1." | 1.32 | A cohort study of the incidence of serious acute liver injury in diabetic patients treated with hypoglycemic agents. ( Ackerson, L; Chan, KA; Everhart, JE; Gurwitz, JH; Hurley, JS; Martinson, B; Moseley, RH; Platt, R; Selby, JV; Terrault, N; Truman, A, 2003) |
| "Metformin is a biguanide commonly used in type 2 diabetes and considered to be a safe drug with minimal side effects." | 1.32 | Metformin induced acute pancreatitis precipitated by renal failure. ( Mallick, S, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (3.23) | 18.2507 |
| 2000's | 11 (35.48) | 29.6817 |
| 2010's | 15 (48.39) | 24.3611 |
| 2020's | 4 (12.90) | 2.80 |
| Authors | Studies |
|---|---|
| Dugic, A | 3 |
| Hagström, H | 3 |
| Dahlman, I | 3 |
| Rutkowski, W | 3 |
| Daou, D | 3 |
| Kulinski, P | 3 |
| Löhr, JM | 3 |
| Vujasinovic, M | 3 |
| Lee, CH | 1 |
| Han, JH | 1 |
| Kim, S | 2 |
| Lee, H | 1 |
| Nam, DH | 1 |
| Cho, DH | 1 |
| Woo, CH | 1 |
| Matyukhin, I | 1 |
| Patschan, S | 1 |
| Ritter, O | 1 |
| Patschan, D | 1 |
| Nguépy Keubo, FR | 1 |
| Mboua, PC | 1 |
| Djifack Tadongfack, T | 1 |
| Fokouong Tchoffo, E | 1 |
| Tasson Tatang, C | 1 |
| Ide Zeuna, J | 1 |
| Noupoue, EM | 1 |
| Tsoplifack, CB | 1 |
| Folefack, GO | 1 |
| Kettani, M | 1 |
| Bandelier, P | 1 |
| Huo, J | 1 |
| Li, H | 4 |
| Yu, D | 1 |
| Arulsamy, N | 1 |
| AlAbbad, S | 1 |
| Sardot, T | 1 |
| Lekashvili, O | 1 |
| Decato, D | 1 |
| Lelj, F | 1 |
| Alexander Ross, JB | 1 |
| Rosenberg, E | 1 |
| Nazir, H | 1 |
| Muthuswamy, N | 1 |
| Louis, C | 1 |
| Jose, S | 1 |
| Prakash, J | 1 |
| Buan, MEM | 1 |
| Flox, C | 1 |
| Chavan, S | 1 |
| Shi, X | 1 |
| Kauranen, P | 1 |
| Kallio, T | 1 |
| Maia, G | 1 |
| Tammeveski, K | 1 |
| Lymperopoulos, N | 1 |
| Carcadea, E | 1 |
| Veziroglu, E | 1 |
| Iranzo, A | 1 |
| M Kannan, A | 1 |
| Arunamata, A | 1 |
| Tacy, TA | 1 |
| Kache, S | 1 |
| Mainwaring, RD | 1 |
| Ma, M | 1 |
| Maeda, K | 1 |
| Punn, R | 1 |
| Noguchi, S | 1 |
| Hahn, S | 3 |
| Iwasa, Y | 3 |
| Ling, J | 2 |
| Voccio, JP | 2 |
| Kim, Y | 3 |
| Song, J | 3 |
| Bascuñán, J | 2 |
| Chu, Y | 1 |
| Tomita, M | 1 |
| Cazorla, M | 1 |
| Herrera, E | 1 |
| Palomeque, E | 1 |
| Saud, N | 1 |
| Hoplock, LB | 1 |
| Lobchuk, MM | 1 |
| Lemoine, J | 1 |
| Li, X | 10 |
| Henson, MA | 1 |
| Unsihuay, D | 1 |
| Qiu, J | 1 |
| Swaroop, S | 1 |
| Nagornov, KO | 1 |
| Kozhinov, AN | 1 |
| Tsybin, YO | 1 |
| Kuang, S | 1 |
| Laskin, J | 1 |
| Zin, NNINM | 1 |
| Mohamad, MN | 1 |
| Roslan, K | 1 |
| Abdul Wafi, S | 1 |
| Abdul Moin, NI | 1 |
| Alias, A | 1 |
| Zakaria, Y | 1 |
| Abu-Bakar, N | 1 |
| Naveed, A | 1 |
| Jilani, K | 1 |
| Siddique, AB | 1 |
| Akbar, M | 1 |
| Riaz, M | 1 |
| Mushtaq, Z | 1 |
| Sikandar, M | 1 |
| Ilyas, S | 1 |
| Bibi, I | 1 |
| Asghar, A | 1 |
| Rasool, G | 1 |
| Irfan, M | 1 |
| Li, XY | 1 |
| Zhao, S | 1 |
| Fan, XH | 1 |
| Chen, KP | 1 |
| Hua, W | 1 |
| Liu, ZM | 1 |
| Xue, XD | 1 |
| Zhou, B | 1 |
| Zhang, S | 2 |
| Xing, YL | 1 |
| Chen, MA | 1 |
| Sun, Y | 1 |
| Neradilek, MB | 1 |
| Wu, XT | 1 |
| Zhang, D | 2 |
| Huang, W | 2 |
| Cui, Y | 1 |
| Yang, QQ | 1 |
| Li, HW | 1 |
| Zhao, XQ | 1 |
| Hossein Rashidi, B | 1 |
| Tarafdari, A | 1 |
| Ghazimirsaeed, ST | 1 |
| Shahrokh Tehraninezhad, E | 1 |
| Keikha, F | 1 |
| Eslami, B | 1 |
| Ghazimirsaeed, SM | 1 |
| Jafarabadi, M | 1 |
| Silvani, Y | 1 |
| Lovita, AND | 1 |
| Maharani, A | 1 |
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| Sujuti, H | 1 |
| Ratnawati, R | 1 |
| Raras, TYM | 1 |
| Lemin, AS | 1 |
| Rahman, MM | 1 |
| Pangarah, CA | 1 |
| Kiyu, A | 1 |
| Zeng, C | 2 |
| Du, H | 1 |
| Lin, D | 1 |
| Jalan, D | 1 |
| Rubagumya, F | 1 |
| Hopman, WM | 1 |
| Vanderpuye, V | 1 |
| Lopes, G | 1 |
| Seruga, B | 1 |
| Booth, CM | 1 |
| Berry, S | 1 |
| Hammad, N | 1 |
| Sajo, EA | 1 |
| Okunade, KS | 1 |
| Olorunfemi, G | 1 |
| Rabiu, KA | 1 |
| Anorlu, RI | 1 |
| Xu, C | 2 |
| Xiang, Y | 1 |
| Xu, X | 1 |
| Zhou, L | 2 |
| Dong, X | 1 |
| Tang, S | 1 |
| Gao, XC | 1 |
| Wei, CH | 1 |
| Zhang, RG | 1 |
| Cai, Q | 1 |
| He, Y | 1 |
| Tong, F | 1 |
| Dong, JH | 1 |
| Wu, G | 1 |
| Dong, XR | 1 |
| Tang, X | 1 |
| Tao, F | 1 |
| Xiang, W | 1 |
| Zhao, Y | 2 |
| Jin, L | 1 |
| Tao, H | 1 |
| Lei, Y | 1 |
| Gan, H | 1 |
| Huang, Y | 1 |
| Chen, Y | 4 |
| Chen, L | 3 |
| Shan, A | 1 |
| Zhao, H | 2 |
| Wu, M | 2 |
| Ma, Q | 1 |
| Wang, J | 4 |
| Zhang, E | 1 |
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| Li, Y | 5 |
| Xue, F | 1 |
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| Yan, Z | 2 |
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| Meng, J | 1 |
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| Anastassiadou, M | 1 |
| Bernasconi, G | 1 |
| Brancato, A | 1 |
| Carrasco Cabrera, L | 1 |
| Greco, L | 1 |
| Jarrah, S | 1 |
| Kazocina, A | 1 |
| Leuschner, R | 1 |
| Magrans, JO | 1 |
| Miron, I | 1 |
| Nave, S | 1 |
| Pedersen, R | 1 |
| Reich, H | 1 |
| Rojas, A | 1 |
| Sacchi, A | 1 |
| Santos, M | 1 |
| Theobald, A | 1 |
| Vagenende, B | 1 |
| Verani, A | 1 |
| Du, L | 1 |
| Liu, X | 1 |
| Ren, Y | 1 |
| Li, J | 8 |
| Li, P | 1 |
| Jiao, Q | 1 |
| Meng, P | 1 |
| Wang, F | 2 |
| Wang, YS | 1 |
| Wang, C | 3 |
| Zhou, X | 2 |
| Wang, W | 1 |
| Wang, S | 2 |
| Hou, J | 1 |
| Zhang, A | 1 |
| Lv, B | 1 |
| Gao, C | 1 |
| Pang, D | 1 |
| Lu, K | 1 |
| Ahmad, NH | 1 |
| Wang, L | 1 |
| Zhu, J | 2 |
| Zhang, L | 3 |
| Zhuang, T | 1 |
| Tu, J | 1 |
| Zhao, Z | 1 |
| Qu, Y | 1 |
| Yao, H | 1 |
| Wang, X | 5 |
| Lee, DF | 1 |
| Shen, J | 3 |
| Wen, L | 1 |
| Huang, G | 2 |
| Xie, X | 1 |
| Zhao, Q | 1 |
| Hu, W | 1 |
| Zhang, Y | 4 |
| Wu, X | 1 |
| Lu, J | 2 |
| Li, M | 1 |
| Li, W | 2 |
| Wu, W | 1 |
| Du, F | 1 |
| Ji, H | 1 |
| Yang, X | 2 |
| Xu, Z | 1 |
| Wan, L | 1 |
| Wen, Q | 1 |
| Cho, CH | 1 |
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| Su, X | 1 |
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| Wei, Y | 2 |
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| Liang, C | 1 |
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| Mi, Y | 1 |
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| Celestrin, CP | 1 |
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5 reviews available for metformin and Acute Disease
| Article | Year |
|---|---|
Etiology and Management of Acute Metabolic Acidosis: An Update.
Topics: Acidosis; Acidosis, Lactic; Acute Disease; Animals; Bicarbonates; Disease Management; Electrolytes; | 2020 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Acute metformin overdose: examining serum pH, lactate level, and metformin concentrations in survivors versus nonsurvivors: a systematic review of the literature.
Topics: Acidosis, Lactic; Acute Disease; Adult; Drug Overdose; Female; Humans; Hydrogen-Ion Concentration; H | 2009 |
[Metformin-induced lactic acidosis].
Topics: Acidosis, Lactic; Acute Disease; Coma; Combined Modality Therapy; Contraindications; Diabetes Mellit | 2000 |
[Should the occurrence of a first coronary event change the management of diabetes?].
Topics: Acidosis, Lactic; Acute Disease; Adrenergic beta-Antagonists; Blood Glucose; Cardiovascular Agents; | 2000 |
4 trials available for metformin and Acute Disease
| Article | Year |
|---|---|
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Leukocyte telomere length and left ventricular function after acute ST-elevation myocardial infarction: data from the glycometabolic intervention as adjunct to primary coronary intervention in ST elevation myocardial infarction (GIPS-III) trial.
Topics: Acute Disease; Causality; Combined Modality Therapy; Comorbidity; Double-Blind Method; Female; Genet | 2015 |
Randomized, double-blind, phase III study to evaluate the efficacy and safety of once-daily treatment with alogliptin and metformin hydrochloride in Japanese patients with type 2 diabetes.
Topics: Acute Disease; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Administrat | 2017 |
Elevated plasma levels of the atherogenic mediator soluble CD40 ligand in diabetic patients: a novel target of thiazolidinediones.
Topics: Acute Disease; Adult; Aged; Arteriosclerosis; Body Mass Index; CD40 Ligand; Chromans; Chronic Diseas | 2003 |
23 other studies available for metformin and Acute Disease
| Article | Year |
|---|---|
Post-pancreatitis diabetes mellitus is common in chronic pancreatitis and is associated with adverse outcomes.
Topics: Acute Disease; Cohort Studies; Diabetes Mellitus, Type 2; Female; Humans; Insulins; Male; Metformin; | 2023 |
Post-pancreatitis diabetes mellitus is common in chronic pancreatitis and is associated with adverse outcomes.
Topics: Acute Disease; Cohort Studies; Diabetes Mellitus, Type 2; Female; Humans; Insulins; Male; Metformin; | 2023 |
Post-pancreatitis diabetes mellitus is common in chronic pancreatitis and is associated with adverse outcomes.
Topics: Acute Disease; Cohort Studies; Diabetes Mellitus, Type 2; Female; Humans; Insulins; Male; Metformin; | 2023 |
Post-pancreatitis diabetes mellitus is common in chronic pancreatitis and is associated with adverse outcomes.
Topics: Acute Disease; Cohort Studies; Diabetes Mellitus, Type 2; Female; Humans; Insulins; Male; Metformin; | 2023 |
Metformin ameliorates bile duct ligation-induced acute hepatic injury via regulation of ER stress.
Topics: Acute Disease; Animals; Bile Ducts; Cholestasis; Disease Models, Animal; Endoplasmic Reticulum Stres | 2020 |
Metformin attenuated endotoxin-induced acute myocarditis via activating AMPK.
Topics: Acute Disease; AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents; Cytokines; Heart; H | 2017 |
Metformin use in diabetics with diverticular disease is associated with reduced incidence of diverticulitis.
Topics: Acute Disease; Aged; Aged, 80 and over; Australia; Case-Control Studies; Diabetes Mellitus, Type 2; | 2017 |
Metformin protects against intestinal barrier dysfunction via AMPKα1-dependent inhibition of JNK signalling activation.
Topics: Acute Disease; Adenylate Kinase; Animals; Bacterial Translocation; Caco-2 Cells; Colitis; Dextran Su | 2018 |
Treatment with incretins does not increase the risk of pancreatic diseases compared to older anti-hyperglycaemic drugs, when added to metformin: real world evidence in people with Type 2 diabetes.
Topics: Acute Disease; Aged; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Drug Therapy, Co | 2019 |
[Effect of metformin added to chemotherapy on the survival of patients with acute lymphoblastic leukemia].
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; D | 2018 |
Chronic Metformin Preconditioning Provides Neuroprotection via Suppression of NF-κB-Mediated Inflammatory Pathway in Rats with Permanent Cerebral Ischemia.
Topics: Acute Disease; Animals; Astrocytes; Brain; Brain Ischemia; Calcium-Binding Proteins; Cytokines; Glia | 2015 |
Hyperlactataemia and clinical severity of acute metformin overdose.
Topics: Acidosis, Lactic; Acute Disease; Adolescent; Adult; Aged; Drug Overdose; Female; Humans; Hyperlactat | 2015 |
Metformin and risk of long-term mortality following an admission for acute heart failure.
Topics: Acute Disease; Aged; Aged, 80 and over; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Heart | 2017 |
Protective Effect of Metformin against Acute Inflammation and Oxidative Stress in Rat.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Carrageenan; Catalase; Diclofenac; Disease Models, | 2016 |
Assessment of Pancreas Safety in the Development Program of Once-Weekly GLP-1 Receptor Agonist Dulaglutide.
Topics: Acute Disease; Diabetes Mellitus, Type 2; Exenatide; Female; Glucagon-Like Peptide-1 Receptor; Gluca | 2017 |
[Toxic metformin-associated acute pancreatitis without kidney failure].
Topics: Acute Disease; Female; Humans; Hypoglycemic Agents; Metformin; Pancreatitis; Renal Insufficiency; Yo | 2008 |
Exenatide and acute pancreatitis.
Topics: Acute Disease; Diabetes Mellitus, Type 2; Drug Interactions; Exenatide; Female; Humans; Hypoglycemic | 2008 |
Acute rhabdomyolysis during treatment with amisulpride and metformin.
Topics: Acute Disease; Adult; Amisulpride; Antipsychotic Agents; Biomarkers; Creatine Kinase, MM Form; Human | 2010 |
Cimetidine-induced lactic acidosis and acute pancreatitis.
Topics: Acidosis, Lactic; Acute Disease; Cimetidine; Diabetes Mellitus, Type 2; Drug Interactions; Female; G | 2010 |
Transient vision loss in a patient with severe metformin-associated lactic acidosis.
Topics: Acidosis, Lactic; Acute Disease; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Humans; Hypoglyc | 2012 |
A cohort study of the incidence of serious acute liver injury in diabetic patients treated with hypoglycemic agents.
Topics: Acute Disease; Adult; Aged; Chemical and Drug Induced Liver Injury; Chromans; Cohort Studies; Female | 2003 |
Metformin induced acute pancreatitis precipitated by renal failure.
Topics: Acidosis, Lactic; Acute Disease; Acute Kidney Injury; Angiotensin-Converting Enzyme Inhibitors; Anti | 2004 |
Metformin-induced pancreatitis: A possible adverse drug effect during acute renal failure.
Topics: Acute Disease; Acute Kidney Injury; Diabetes Mellitus; Female; Humans; Hypoglycemic Agents; Metformi | 2006 |
Metformin-induced lactic acidosis and acute pancreatitis precipitated by diuretic, celecoxib, and candesartan-associated acute kidney dysfunction.
Topics: Acidosis, Lactic; Acute Disease; Acute Kidney Injury; Angiotensin II Type 1 Receptor Blockers; Benzi | 2008 |
Metformin-induced acute hepatitis.
Topics: Acute Disease; Alanine Transaminase; Alkaline Phosphatase; Bilirubin; Biopsy; Chemical and Drug Indu | 1998 |
Metformin associated acute pancreatitis.
Topics: Acute Disease; Adult; Amylases; Female; Humans; Hypoglycemic Agents; Lipase; Metformin; Pancreatitis | 2002 |