metformin has been researched along with Acquired Nephrogenic Diabetes Insipidus in 4 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This is especially true for nephrogenic diabetes insipidus (NDI)." | 2.53 | Physiological insights into novel therapies for nephrogenic diabetes insipidus. ( Klein, JD; Sands, JM, 2016) |
| "With metformin treatment, the blood osmolality decreased from 328." | 1.62 | Protective effect of metformin on lithium-induced nephrogenic diabetes insipidus: An experimental study in rats. ( Sancak, EB; Tas, HI, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tas, HI | 1 |
| Sancak, EB | 1 |
| Bech, AP | 1 |
| Wetzels, JFM | 1 |
| Nijenhuis, T | 1 |
| Klein, JD | 2 |
| Wang, Y | 1 |
| Blount, MA | 1 |
| Molina, PA | 1 |
| LaRocque, LM | 1 |
| Ruiz, JA | 1 |
| Sands, JM | 2 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Correction of Hypernatremia by Intravenous Hypotonic Solution Compared to Enteral Water, Randomized Clinical Trial[NCT06061783] | 178 participants (Anticipated) | Interventional | 2023-11-30 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for metformin and Acquired Nephrogenic Diabetes Insipidus
| Article | Year |
|---|---|
Physiological insights into novel therapies for nephrogenic diabetes insipidus.
Topics: Adenylate Kinase; Animals; Aquaporin 2; Diabetes Insipidus, Nephrogenic; Erlotinib Hydrochloride; Hu | 2016 |
1 trial available for metformin and Acquired Nephrogenic Diabetes Insipidus
| Article | Year |
|---|---|
Effects of sildenafil, metformin, and simvastatin on ADH-independent urine concentration in healthy volunteers.
Topics: Adult; Diabetes Insipidus, Nephrogenic; Female; Healthy Volunteers; Humans; Kidney; Male; Metformin; | 2018 |
2 other studies available for metformin and Acquired Nephrogenic Diabetes Insipidus
| Article | Year |
|---|---|
Protective effect of metformin on lithium-induced nephrogenic diabetes insipidus: An experimental study in rats.
Topics: Animals; Aquaporin 2; Diabetes Insipidus, Nephrogenic; Diabetes Mellitus, Type 2; Humans; Lithium; M | 2021 |
Metformin, an AMPK activator, stimulates the phosphorylation of aquaporin 2 and urea transporter A1 in inner medullary collecting ducts.
Topics: AMP-Activated Protein Kinases; Animals; Aquaporin 2; Diabetes Insipidus, Nephrogenic; Drug Evaluatio | 2016 |