metformin has been researched along with Acne Inversa in 18 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In metformin-treated patients, these metabolic pathways were restored and their PBMCs had reduced inflammatory markers following long-term metformin treatment." | 5.91 | Metformin has anti-inflammatory effects and induces immunometabolic reprogramming via multiple mechanisms in hidradenitis suppurativa. ( Almeida, JP; Boland, PA; Fletcher, JM; Hambly, R; Ismaiel, M; Kearney, N; Kennedy, C; Kirby, B; Mac Mahon, J; Murphy, S; O'Rourke, AM; Pender, EK; Petrasca, A; Smith, CM; Winter, D; Zaborowski, A, 2023) |
| "The aim of the study was to investigate immune-mediated (urticaria, allergic contact dermatitis, and psoriasis) and androgen-mediated (acanthosis nigricans, hidradenitis suppurativa, and acne) skin diseases associated with metformin use." | 4.31 | Differential Effects of Metformin on Immune-Mediated and Androgen-Mediated Non-Cancer Skin Diseases in Diabetes Patients: A Retrospective Cohort Study. ( Tseng, CH, 2023) |
| "Hormonal treatments in hidradenitis suppurativa: a systematic review." | 3.01 | Hormonal Treatments in Hidradenitis Suppurativa: A Systematic Review. ( Hsiao, JL; Jeong, C; Masson, R; Shi, VY; Shih, T, 2023) |
| "Hidradenitis suppurativa/acne inversa is a disease with deep-seated chronic painful nodules, abscesses, and draining sinus tracts, which manifests on the apocrine gland-rich skin areas of the body." | 2.61 | Is There a Role for Antiandrogen Therapy for Hidradenitis Suppurativa? A Systematic Review of Published Data. ( Kyrgidis, A; Nikolakis, G; Zouboulis, CC, 2019) |
| "The management of hidradenitis suppurativa is multidisciplinary, involving general measures, medical treatment and surgery." | 2.55 | Non-surgical treatments for hidradenitis suppurativa: A systematic review. ( Bodin, F; Chaput, B; Gall, Y; Grolleau, JL; Konstantinou, MP; Laloze, J; Paul, C; Robert, E, 2017) |
| "Hidradenitis suppurativa is a debilitating inflammatory skin disease with a chronic course and often disappointing response to treatment." | 2.55 | Management of hidradenitis suppurativa in pregnancy. ( Okoye, GA; Perng, P; Zampella, JG, 2017) |
| "Hidradenitis suppurativa is a common debilitating skin disease that has been neglected by science." | 2.53 | Medical Treatments of Hidradenitis Suppurativa: More Options, Less Evidence. ( Gulliver, WP; van der Zee, HH, 2016) |
| "In metformin-treated patients, these metabolic pathways were restored and their PBMCs had reduced inflammatory markers following long-term metformin treatment." | 1.91 | Metformin has anti-inflammatory effects and induces immunometabolic reprogramming via multiple mechanisms in hidradenitis suppurativa. ( Almeida, JP; Boland, PA; Fletcher, JM; Hambly, R; Ismaiel, M; Kearney, N; Kennedy, C; Kirby, B; Mac Mahon, J; Murphy, S; O'Rourke, AM; Pender, EK; Petrasca, A; Smith, CM; Winter, D; Zaborowski, A, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (5.56) | 29.6817 |
| 2010's | 8 (44.44) | 24.3611 |
| 2020's | 9 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tseng, CH | 1 |
| Hambly, R | 2 |
| Kearney, N | 2 |
| Hughes, R | 1 |
| Fletcher, JM | 2 |
| Kirby, B | 2 |
| Moreno, A | 1 |
| Williams, SC | 1 |
| Goto, R | 1 |
| Krueger, JG | 1 |
| Renert-Yuval, Y | 1 |
| Masson, R | 1 |
| Shih, T | 1 |
| Jeong, C | 1 |
| Shi, VY | 1 |
| Hsiao, JL | 1 |
| Petrasca, A | 1 |
| Smith, CM | 1 |
| Pender, EK | 1 |
| Mac Mahon, J | 1 |
| O'Rourke, AM | 1 |
| Ismaiel, M | 1 |
| Boland, PA | 1 |
| Almeida, JP | 1 |
| Kennedy, C | 1 |
| Zaborowski, A | 1 |
| Murphy, S | 1 |
| Winter, D | 1 |
| Melnik, BC | 1 |
| Chang, JE | 1 |
| Choi, MS | 1 |
| Moussa, C | 1 |
| Wadowski, L | 1 |
| Price, H | 1 |
| Mirea, L | 1 |
| O'Haver, J | 1 |
| Robert, E | 1 |
| Bodin, F | 1 |
| Paul, C | 1 |
| Konstantinou, MP | 1 |
| Gall, Y | 1 |
| Grolleau, JL | 1 |
| Laloze, J | 1 |
| Chaput, B | 1 |
| Nikolakis, G | 1 |
| Kyrgidis, A | 1 |
| Zouboulis, CC | 1 |
| Scheinfeld, N | 1 |
| Kerdel, FA | 1 |
| van der Zee, HH | 1 |
| Gulliver, WP | 1 |
| Perng, P | 1 |
| Zampella, JG | 1 |
| Okoye, GA | 1 |
| Riis, PT | 1 |
| Ring, HC | 1 |
| Themstrup, L | 1 |
| Jemec, GB | 1 |
| Arun, B | 1 |
| Loffeld, A | 1 |
| Verdolini, R | 1 |
| Clayton, N | 1 |
| Smith, A | 1 |
| Alwash, N | 1 |
| Mannello, B | 1 |
8 reviews available for metformin and Acne Inversa
| Article | Year |
|---|---|
Hormonal Treatments in Hidradenitis Suppurativa: A Systematic Review.
Topics: Finasteride; Flutamide; Hidradenitis Suppurativa; Humans; Liraglutide; Metformin; Spironolactone | 2023 |
A Molecular Perspective on the Potential Benefits of Metformin for the Treatment of Inflammatory Skin Disorders.
Topics: Acanthosis Nigricans; Acne Vulgaris; Dermatitis, Allergic Contact; Hidradenitis Suppurativa; Humans; | 2020 |
Non-surgical treatments for hidradenitis suppurativa: A systematic review.
Topics: Androgen Antagonists; Anti-Bacterial Agents; Anti-Inflammatory Agents; Biological Products; Dermatol | 2017 |
Is There a Role for Antiandrogen Therapy for Hidradenitis Suppurativa? A Systematic Review of Published Data.
Topics: Androgen Antagonists; Androgens; Cyproterone Acetate; Drug Therapy, Combination; Finasteride; Hidrad | 2019 |
Hidradenitis suppurativa: A practical review of possible medical treatments based on over 350 hidradenitis patients.
Topics: Abscess; Anti-Bacterial Agents; Anti-Inflammatory Agents; Bandages; Biofilms; Combined Modality Ther | 2013 |
Medical Treatments of Hidradenitis Suppurativa: More Options, Less Evidence.
Topics: Acitretin; Adrenal Cortex Hormones; Anti-Infective Agents; Cyclosporine; Dapsone; Dermatologic Agent | 2016 |
Management of hidradenitis suppurativa in pregnancy.
Topics: Anti-Bacterial Agents; Biological Products; Contraindications; Cryotherapy; Female; Hidradenitis Sup | 2017 |
The Role of Androgens and Estrogens in Hidradenitis Suppurativa - A Systematic Review.
Topics: Adult; Age Distribution; Androgens; Chronic Disease; Denmark; Estrogens; Female; Hidradenitis Suppur | 2016 |
10 other studies available for metformin and Acne Inversa
| Article | Year |
|---|---|
Differential Effects of Metformin on Immune-Mediated and Androgen-Mediated Non-Cancer Skin Diseases in Diabetes Patients: A Retrospective Cohort Study.
Topics: Acne Vulgaris; Androgens; Diabetes Mellitus, Type 2; Hidradenitis Suppurativa; Humans; Metformin; Re | 2023 |
Metformin Treatment of Hidradenitis Suppurativa: Effect on Metabolic Parameters, Inflammation, Cardiovascular Risk Biomarkers, and Immune Mediators.
Topics: Adipokines; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Case-Control Studies; Heart Dis | 2023 |
A systematic review and critical appraisal of pharmacological treatments for pediatric hidradenitis suppurativa.
Topics: Child; Hidradenitis Suppurativa; Humans; Immunosuppressive Agents; Metformin; Systematic Reviews as | 2023 |
Metformin has anti-inflammatory effects and induces immunometabolic reprogramming via multiple mechanisms in hidradenitis suppurativa.
Topics: Anti-Inflammatory Agents; Cytokines; Hidradenitis Suppurativa; Humans; Leukocytes, Mononuclear; Metf | 2023 |
Metformin attenuates mechanistic target of rapamycin complex 1/hypoxia-inducible factor-1α-driven glycolysis reducing keratinocyte and T helper 17 cell proliferation in hyperproliferative inflammatory skin diseases.
Topics: Anti-Inflammatory Agents; Cell Proliferation; Glycolysis; Hidradenitis Suppurativa; Humans; Hypoxia- | 2023 |
The antidiabetic medicine metformin has beneficial effects in hidradenitis suppurativa.
Topics: Anti-Inflammatory Agents; Hidradenitis Suppurativa; Humans; Hypoglycemic Agents; Metformin | 2023 |
Metformin as Adjunctive Therapy for Pediatric Patients With Hidradenitis Suppurativa.
Topics: Adolescent; Anti-Bacterial Agents; Child; Cross-Sectional Studies; Drug Therapy, Combination; Female | 2020 |
Current and emerging nonsurgical treatment options for hidradenitis suppurativa.
Topics: Adalimumab; Adrenal Cortex Hormones; Anti-Bacterial Agents; Antibodies, Monoclonal; Antibodies, Mono | 2014 |
Long-standing hidradenitis suppurativa treated effectively with metformin.
Topics: Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Female; Hidradenitis Suppurativa; Human | 2009 |
Metformin for the treatment of hidradenitis suppurativa: a little help along the way.
Topics: Adolescent; Adult; Female; Hidradenitis Suppurativa; Humans; Male; Metformin; Middle Aged; Young Adu | 2013 |