metformin has been researched along with Acid-Base Imbalance in 2 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Acid-Base Imbalance: Disturbances in the ACID-BASE EQUILIBRIUM of the body.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metformin-associated lactic acidosis (MALA) is a rare adverse effect that has significant morbidity and mortality." | 9.05 | Osmolar-gap in the setting of metformin-associated lactic acidosis: Case report and a literature review highlighting an apparently unusual association. ( Alamin, M; Elshafei, MN; Mohamed, MFH, 2020) |
| "Metformin-associated lactic acidosis (MALA) is a rare adverse effect that has significant morbidity and mortality." | 5.05 | Osmolar-gap in the setting of metformin-associated lactic acidosis: Case report and a literature review highlighting an apparently unusual association. ( Alamin, M; Elshafei, MN; Mohamed, MFH, 2020) |
| "Metformin use has been associated with the development of lactic acidosis, although many studies have doubt the direct link with this serious complication." | 2.55 | Acid-base and electrolyte disorders associated with the use of antidiabetic drugs. ( Elisaf, M; Filippatos, T; Liamis, G; Rizos, C; Tzavella, E, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Elshafei, MN | 1 |
| Alamin, M | 1 |
| Mohamed, MFH | 1 |
| Filippatos, T | 1 |
| Tzavella, E | 1 |
| Rizos, C | 1 |
| Elisaf, M | 1 |
| Liamis, G | 1 |
2 reviews available for metformin and Acid-Base Imbalance
| Article | Year |
|---|---|
Osmolar-gap in the setting of metformin-associated lactic acidosis: Case report and a literature review highlighting an apparently unusual association.
Topics: Acid-Base Imbalance; Acidosis, Lactic; Acute Kidney Injury; Diabetes Mellitus, Type 2; Humans; Hypog | 2020 |
Acid-base and electrolyte disorders associated with the use of antidiabetic drugs.
Topics: Acid-Base Equilibrium; Acid-Base Imbalance; Animals; Diabetes Mellitus, Type 2; Humans; Hypoglycemic | 2017 |