metformin has been researched along with Abortion, Spontaneous in 51 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Abortion, Spontaneous: Expulsion of the product of FERTILIZATION before completing the term of GESTATION and without deliberate interference.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In pregnant women with PCOS, metformin treatment from the late first trimester until delivery might reduce the risk of late miscarriage and preterm birth, but does not prevent gestational diabetes." | 9.30 | Use of metformin to treat pregnant women with polycystic ovary syndrome (PregMet2): a randomised, double-blind, placebo-controlled trial. ( Andræ, F; Berg, AH; Bixo, M; Carlsen, SM; Gómez-Real, F; Hestvold, KV; Hirschberg, AL; Hjelle, S; Lønnebotn, M; Løvvik, TS; Mohlin, J; Poromaa, IS; Salvesen, Ø; Steffensen, B; Thorarinsdottir, S; Trouva, A; Underdal, M; Vanky, E; Zabielska, R, 2019) |
| "To evaluate the efficacy and safety of using metformin in pregnant women with polycystic ovarian syndrome (PCOS) and to explore the most effective and safe protocol by using a meta-analysis method." | 9.22 | Efficacy and safety of metformin in pregnant women with polycystic ovary syndrome: a systematic review with meta-analysis of randomized and non-randomized controlled trials. ( He, J; Zhao, Q, 2022) |
| "In 76 PCOS women, first pregnancy miscarriage and live birth were compared before and on metformin/diet, started 6." | 9.17 | Effects of metformin-diet intervention before and throughout pregnancy on obstetric and neonatal outcomes in patients with polycystic ovary syndrome. ( Glueck, CJ; Goldenberg, N; Khan, Z; Padda, J; Pranikoff, J; Wang, P, 2013) |
| "The role of metformin in the treatment of infertility in women with polycystic ovary syndrome (PCOS) is still controversial." | 9.16 | Metformin improves pregnancy and live-birth rates in women with polycystic ovary syndrome (PCOS): a multicenter, double-blind, placebo-controlled randomized trial. ( Bloigu, R; Hippeläinen, M; Morin-Papunen, L; Perheentupa, A; Puukka, K; Rantala, AS; Ruokonen, A; Tapanainen, JS; Tiitinen, A; Tinkanen, H; Unkila-Kallio, L, 2012) |
| "To prospectively evaluate the safety of metformin administration during pregnancy in a group of PCOS patients by assessing its effect on the prevalence of gestational complications and neonatal outcome." | 9.15 | The administration of metformin during pregnancy reduces polycystic ovary syndrome related gestational complications. ( De Leo, V; Di Sabatino, A; Morgante, G; Musacchio, MC; Piomboni, P, 2011) |
| "According to the current findings, it seems that continuing metformin during the first trimester of pregnancy has beneficial effects in patients with PCOS." | 9.14 | Effect of metformin on miscarriage in pregnant patients with polycystic ovary syndrome. ( Bagheri, B; Haghollahi, F; Shariat, M; Sohrabvand, F, 2009) |
| "The purpose of this study was to compare the effectiveness of laparoscopic ovarian diathermy (LOD) vs clomiphene citrate (CC) plus metformin in infertile patients with CC-resistant polycystic ovary syndrome (PCOS)." | 9.14 | Laparoscopic ovarian diathermy vs clomiphene citrate plus metformin as second-line strategy for infertile anovulatory patients with polycystic ovary syndrome: a randomized controlled trial. ( Battista, L; Falbo, A; Orio, F; Palomba, S; Russo, T; Tolino, A; Venturella, R; Zullo, F, 2010) |
| "The efficacy of metformin-CC combination therapy is higher than that of NAC-CC for inducing ovulation and achieving pregnancy among CC-resistant PCOS patients." | 9.14 | N-acetyl cysteine plus clomiphene citrate versus metformin and clomiphene citrate in treatment of clomiphene-resistant polycystic ovary syndrome: a randomized controlled trial. ( Abu Hashim, H; Anwar, K; El-Fatah, RA, 2010) |
| "Administration of metformin throughout pregnancy to women with PCOS was associated with a marked and significant reduction in the rate of early pregnancy loss." | 9.12 | Metformin reduces abortion in pregnant women with polycystic ovary syndrome. ( Al-Inany, H; Foutouh, IA; Khattab, S; Moaz, M; Mohsen, IA; Ramadan, A, 2006) |
| "To determine whether metformin would safely reduce the rate of first-trimester spontaneous abortion without teratogenicity in 19 women with the polycystic ovary syndrome (PCOS)." | 9.09 | Continuing metformin throughout pregnancy in women with polycystic ovary syndrome appears to safely reduce first-trimester spontaneous abortion: a pilot study. ( Cameron, D; Glueck, CJ; Phillips, H; Sieve-Smith, L; Wang, P, 2001) |
| " Insulin-sensitising agents such as metformin may be effective in treating PCOS-related anovulation." | 8.95 | Insulin-sensitising drugs (metformin, rosiglitazone, pioglitazone, D-chiro-inositol) for women with polycystic ovary syndrome, oligo amenorrhoea and subfertility. ( Balen, AH; Morley, LC; Norman, RJ; Tang, T; Yasmin, E, 2017) |
| "Our results showed that continued use during of metformin, during pregnancy in women with PCOS, had no effect on incidence of fetal abnormalities or fetal birth weight." | 8.93 | Effect of metformin treatment during pregnancy on women with PCOS: a systematic review and meta-analysis. ( Chang, Y; Fang, C; Li, S; Liu, H; Tan, X; Wang, Y; Zhang, X, 2016) |
| "Databases were searched for reports published in English between 2002 and 2013, using combinations of the terms "polycystic ovary syndrome," "PCOS," "insulin-sensitizing," and "metformin." | 8.91 | A systematic review and meta-analysis of metformin among patients with polycystic ovary syndrome undergoing assisted reproductive technology procedures. ( Huang, X; Li, Y; Lv, F; Tal, R; Wang, P; Zhang, X, 2015) |
| "To evaluate the efficacy of metformin administration throughout pregnancy on pregnancy-related complications in women with polycystic ovary syndrome (PCOS)." | 8.91 | Efficacy of metformin on pregnancy complications in women with polycystic ovary syndrome: a meta-analysis. ( Du, YK; Feng, L; Hu, D; Lin, XF; Wan, ZH, 2015) |
| "In infertile patients with PCOS treated with gonadotrophins for IVF/ICSI cycles, metformin exerts no clinical effect on rates of pregnancy or live birth, but it reduces the risk of OHSS, and improves the rates of miscarriage and implantation." | 8.89 | Effects of metformin in women with polycystic ovary syndrome treated with gonadotrophins for in vitro fertilisation and intracytoplasmic sperm injection cycles: a systematic review and meta-analysis of randomised controlled trials. ( Falbo, A; La Sala, GB; Palomba, S, 2013) |
| "This article is a review of the literature assessing pregnancy outcomes and the effect of metformin treatment among women with polycystic ovary syndrome (PCOS)." | 8.88 | Pregnancy outcomes and the effect of metformin treatment in women with polycystic ovary syndrome: an overview. ( Awwad, JT; Ghazeeri, GS; Nassar, AH; Younes, Z, 2012) |
| "To evaluate the effect of pregestational metformin administration on abortion risk in polycystic ovary syndrome (PCOS) patients." | 8.85 | Effect of preconceptional metformin on abortion risk in polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trials. ( Falbo, A; Orio, F; Palomba, S; Zullo, F, 2009) |
| " The most extensively studied insulin-lowering agent in the treatment of PCOS is metformin: an oral antihyperglycaemic agent used initially in the treatment of type 2 diabetes mellitus." | 8.81 | Should patients with polycystic ovarian syndrome be treated with metformin? ( Duleba, AJ; Seli, E, 2002) |
| "Clinicians who treat pregnant women with metformin should be aware of the significant decrease in metformin concentration mediated by pregnancy, and the rapid increase after delivery, as it may impact both the therapeutic efficacy and the risk of adverse drug reactions." | 8.12 | Metformin serum concentrations during pregnancy and post partum - A clinical study in patients with polycystic ovary syndrome. ( Espnes, KA; Gundersen, POM; Hønnås, A; Løvvik, TS; Naavik, A; Skogvoll, E; Spigset, O; Vanky, E; Westin, AA, 2022) |
| "Pregnant women with pre-gestational diabetes on metformin are at a higher risk for adverse pregnancy outcomes than the general population." | 7.88 | Pregnancy outcomes in women on metformin for diabetes or other indications among those seeking teratology information services. ( Amar, E; Baud, D; Beau-Salinas, F; Bernard, N; Buclin, T; Cassina, M; Csajka, C; Dautriche, A; De Santis, M; Duman, MK; Dunstan, H; Eleftheriou, G; Hernandez-Diaz, S; Kaplan, YC; Klinger, G; Maňáková, E; Panchaud, A; Passier, A; Pistelli, A; Rothuizen, LE; Rousson, V; Vial, T; Winterfeld, U, 2018) |
| "The aim of this study was to evaluate the risk of major birth defects and spontaneous abortion after metformin use during the first trimester of pregnancy." | 7.88 | Pregnancy outcome after first-trimester exposure to metformin: A prospective cohort study. ( Beck, E; Grupe, K; Schaefer, C; Scherneck, S; Schlinke, N; Weber-Schoendorfer, C, 2018) |
| "There were 56 patients who received metformin during pregnancy (metformin group) compared with 50 patients who did not receive the treatment (control group)." | 7.81 | Effect of metformin on early pregnancy loss in women with polycystic ovary syndrome. ( Al-Biate, MA, 2015) |
| "In women with polycystic ovary syndrome, metformin administration, not laparoscopic ovarian drilling, reduces plasminogen activator inhibitor 1 (PAI-1) activity." | 7.73 | Plasminogen activator inhibitor 1 and miscarriage after metformin treatment and laparoscopic ovarian drilling in patients with polycystic ovary syndrome. ( Falbo, A; Orio, F; Palomba, S; Russo, T; Tolino, A; Zullo, F, 2005) |
| "Metformin therapy during pregnancy in women with PCOS was safely associated with reduction in SAB and in GD, was not teratogenic, and did not adversely affect birthweight or height, or height, weight, and motor and social development at 3 and 6 months of life." | 7.71 | Pregnancy outcomes among women with polycystic ovary syndrome treated with metformin. ( Glueck, CJ; Goldenberg, N; Sieve-Smith, L; Wang, P, 2002) |
| " No adverse maternal-fetal side effects were reported on enoxaparin alone or enoxaparin-metformin." | 6.74 | Enoxaparin-metformin and enoxaparin alone may safely reduce pregnancy loss. ( Glueck, CJ; Goldenberg, N; Khan, N; Ramidi, G; Wang, P, 2009) |
| "When metformin was compared with CC, data for live birth were inconclusive, and the findings were limited by lack of evidence." | 6.61 | Metformin for ovulation induction (excluding gonadotrophins) in women with polycystic ovary syndrome. ( Balen, AH; Morley, LC; Norman, RJ; Sharpe, A; Tang, T, 2019) |
| "Polycystic ovary syndrome is characterized among other things by oligo-amenorrhea and may account for more than 75% of cases with anoluvatory infertility." | 6.43 | Is metformin therapy for polycystic ovary syndrome safe during pregnancy? ( Brock, B; Ovesen, P; Rungby, J; Schmitz, O; Smidt, K, 2005) |
| "A total of 27 RCTs with 12 interventions were included, and all therapies tended to increase clinical pregnancy, especially pioglitazone (PIO) (log OR 3." | 5.41 | The effects of first-line pharmacological treatments for reproductive outcomes in infertile women with PCOS: a systematic review and network meta-analysis. ( Li, J; Liu, Y; Ma, J; Peng, G; Tong, N; Wang, Y; Yan, Z, 2023) |
| "Polycystic ovary syndrome is the most common form of female infertility in the United States." | 5.31 | Effects of metformin on early pregnancy loss in the polycystic ovary syndrome. ( Iuorno, MJ; Jakubowicz, DJ; Jakubowicz, S; Nestler, JE; Roberts, KA, 2002) |
| "In pregnant women with PCOS, metformin treatment from the late first trimester until delivery might reduce the risk of late miscarriage and preterm birth, but does not prevent gestational diabetes." | 5.30 | Use of metformin to treat pregnant women with polycystic ovary syndrome (PregMet2): a randomised, double-blind, placebo-controlled trial. ( Andræ, F; Berg, AH; Bixo, M; Carlsen, SM; Gómez-Real, F; Hestvold, KV; Hirschberg, AL; Hjelle, S; Lønnebotn, M; Løvvik, TS; Mohlin, J; Poromaa, IS; Salvesen, Ø; Steffensen, B; Thorarinsdottir, S; Trouva, A; Underdal, M; Vanky, E; Zabielska, R, 2019) |
| "To evaluate the efficacy and safety of using metformin in pregnant women with polycystic ovarian syndrome (PCOS) and to explore the most effective and safe protocol by using a meta-analysis method." | 5.22 | Efficacy and safety of metformin in pregnant women with polycystic ovary syndrome: a systematic review with meta-analysis of randomized and non-randomized controlled trials. ( He, J; Zhao, Q, 2022) |
| "In 76 PCOS women, first pregnancy miscarriage and live birth were compared before and on metformin/diet, started 6." | 5.17 | Effects of metformin-diet intervention before and throughout pregnancy on obstetric and neonatal outcomes in patients with polycystic ovary syndrome. ( Glueck, CJ; Goldenberg, N; Khan, Z; Padda, J; Pranikoff, J; Wang, P, 2013) |
| "The role of metformin in the treatment of infertility in women with polycystic ovary syndrome (PCOS) is still controversial." | 5.16 | Metformin improves pregnancy and live-birth rates in women with polycystic ovary syndrome (PCOS): a multicenter, double-blind, placebo-controlled randomized trial. ( Bloigu, R; Hippeläinen, M; Morin-Papunen, L; Perheentupa, A; Puukka, K; Rantala, AS; Ruokonen, A; Tapanainen, JS; Tiitinen, A; Tinkanen, H; Unkila-Kallio, L, 2012) |
| "To prospectively evaluate the safety of metformin administration during pregnancy in a group of PCOS patients by assessing its effect on the prevalence of gestational complications and neonatal outcome." | 5.15 | The administration of metformin during pregnancy reduces polycystic ovary syndrome related gestational complications. ( De Leo, V; Di Sabatino, A; Morgante, G; Musacchio, MC; Piomboni, P, 2011) |
| "The efficacy of metformin-CC combination therapy is higher than that of NAC-CC for inducing ovulation and achieving pregnancy among CC-resistant PCOS patients." | 5.14 | N-acetyl cysteine plus clomiphene citrate versus metformin and clomiphene citrate in treatment of clomiphene-resistant polycystic ovary syndrome: a randomized controlled trial. ( Abu Hashim, H; Anwar, K; El-Fatah, RA, 2010) |
| "According to the current findings, it seems that continuing metformin during the first trimester of pregnancy has beneficial effects in patients with PCOS." | 5.14 | Effect of metformin on miscarriage in pregnant patients with polycystic ovary syndrome. ( Bagheri, B; Haghollahi, F; Shariat, M; Sohrabvand, F, 2009) |
| "The purpose of this study was to compare the effectiveness of laparoscopic ovarian diathermy (LOD) vs clomiphene citrate (CC) plus metformin in infertile patients with CC-resistant polycystic ovary syndrome (PCOS)." | 5.14 | Laparoscopic ovarian diathermy vs clomiphene citrate plus metformin as second-line strategy for infertile anovulatory patients with polycystic ovary syndrome: a randomized controlled trial. ( Battista, L; Falbo, A; Orio, F; Palomba, S; Russo, T; Tolino, A; Venturella, R; Zullo, F, 2010) |
| "Administration of metformin throughout pregnancy to women with PCOS was associated with a marked and significant reduction in the rate of early pregnancy loss." | 5.12 | Metformin reduces abortion in pregnant women with polycystic ovary syndrome. ( Al-Inany, H; Foutouh, IA; Khattab, S; Moaz, M; Mohsen, IA; Ramadan, A, 2006) |
| "To determine whether metformin would safely reduce the rate of first-trimester spontaneous abortion without teratogenicity in 19 women with the polycystic ovary syndrome (PCOS)." | 5.09 | Continuing metformin throughout pregnancy in women with polycystic ovary syndrome appears to safely reduce first-trimester spontaneous abortion: a pilot study. ( Cameron, D; Glueck, CJ; Phillips, H; Sieve-Smith, L; Wang, P, 2001) |
| " Insulin-sensitising agents such as metformin may be effective in treating PCOS-related anovulation." | 4.95 | Insulin-sensitising drugs (metformin, rosiglitazone, pioglitazone, D-chiro-inositol) for women with polycystic ovary syndrome, oligo amenorrhoea and subfertility. ( Balen, AH; Morley, LC; Norman, RJ; Tang, T; Yasmin, E, 2017) |
| "Our results showed that continued use during of metformin, during pregnancy in women with PCOS, had no effect on incidence of fetal abnormalities or fetal birth weight." | 4.93 | Effect of metformin treatment during pregnancy on women with PCOS: a systematic review and meta-analysis. ( Chang, Y; Fang, C; Li, S; Liu, H; Tan, X; Wang, Y; Zhang, X, 2016) |
| "Databases were searched for reports published in English between 2002 and 2013, using combinations of the terms "polycystic ovary syndrome," "PCOS," "insulin-sensitizing," and "metformin." | 4.91 | A systematic review and meta-analysis of metformin among patients with polycystic ovary syndrome undergoing assisted reproductive technology procedures. ( Huang, X; Li, Y; Lv, F; Tal, R; Wang, P; Zhang, X, 2015) |
| "To evaluate the efficacy of metformin administration throughout pregnancy on pregnancy-related complications in women with polycystic ovary syndrome (PCOS)." | 4.91 | Efficacy of metformin on pregnancy complications in women with polycystic ovary syndrome: a meta-analysis. ( Du, YK; Feng, L; Hu, D; Lin, XF; Wan, ZH, 2015) |
| "In infertile patients with PCOS treated with gonadotrophins for IVF/ICSI cycles, metformin exerts no clinical effect on rates of pregnancy or live birth, but it reduces the risk of OHSS, and improves the rates of miscarriage and implantation." | 4.89 | Effects of metformin in women with polycystic ovary syndrome treated with gonadotrophins for in vitro fertilisation and intracytoplasmic sperm injection cycles: a systematic review and meta-analysis of randomised controlled trials. ( Falbo, A; La Sala, GB; Palomba, S, 2013) |
| "This article is a review of the literature assessing pregnancy outcomes and the effect of metformin treatment among women with polycystic ovary syndrome (PCOS)." | 4.88 | Pregnancy outcomes and the effect of metformin treatment in women with polycystic ovary syndrome: an overview. ( Awwad, JT; Ghazeeri, GS; Nassar, AH; Younes, Z, 2012) |
| "Compared with clomiphene citrate, metformin used for ovulation induction treatment in PCOS women, can promote ovulation induction and pregnancy rate, the effect of the combination treatment is better than that of a single drug use." | 4.88 | The effectiveness of metformin ovulation induction treatment in patients with PCOS: a systematic review and meta-analysis. ( Chang, S; Chen, S; Xiao, J; Zhang, C, 2012) |
| " The Pregnancy in PCOS trial II will determine the safety and efficacy of clomiphene citrate compared to letrozole, in achieving live birth in infertile women with PCOS." | 4.88 | Reproductive impact of polycystic ovary syndrome. ( Legro, RS; Usadi, RS, 2012) |
| "To evaluate the effect of pregestational metformin administration on abortion risk in polycystic ovary syndrome (PCOS) patients." | 4.85 | Effect of preconceptional metformin on abortion risk in polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trials. ( Falbo, A; Orio, F; Palomba, S; Zullo, F, 2009) |
| "Metformin is a common treatment for women who have insulin resistance manifesting as type 2 diabetes or polycystic ovarian syndrome (PCOS)." | 4.82 | Metformin in obstetric and gynecologic practice: a review. ( Boyle, J; McCarthy, EA; McLachlan, K; Permezel, M; Walker, SP, 2004) |
| "The use of metformin in early pregnancy for reducing the risk of miscarriage should be avoided outside of the context of properly designed prospective randomized trials." | 4.82 | Should we continue or stop insulin sensitizing drugs during pregnancy? ( Hague, W; Norman, RJ; Wang, JX, 2004) |
| " The most extensively studied insulin-lowering agent in the treatment of PCOS is metformin: an oral antihyperglycaemic agent used initially in the treatment of type 2 diabetes mellitus." | 4.81 | Should patients with polycystic ovarian syndrome be treated with metformin? ( Duleba, AJ; Seli, E, 2002) |
| " Metformin treatment reduces the risk of late miscarriage and preterm birth in pregnant women with PCOS." | 4.31 | Immunomodulatory Effects of Metformin Treatment in Pregnant Women With PCOS. ( Giskeødegård, GF; Iversen, AC; Jarmund, AH; Løvvik, TS; Madssen, TS; Ryssdal, M; Steinkjer, B; Stokkeland, LMT; Vanky, E, 2023) |
| "Clinicians who treat pregnant women with metformin should be aware of the significant decrease in metformin concentration mediated by pregnancy, and the rapid increase after delivery, as it may impact both the therapeutic efficacy and the risk of adverse drug reactions." | 4.12 | Metformin serum concentrations during pregnancy and post partum - A clinical study in patients with polycystic ovary syndrome. ( Espnes, KA; Gundersen, POM; Hønnås, A; Løvvik, TS; Naavik, A; Skogvoll, E; Spigset, O; Vanky, E; Westin, AA, 2022) |
| "Pregnant women with pre-gestational diabetes on metformin are at a higher risk for adverse pregnancy outcomes than the general population." | 3.88 | Pregnancy outcomes in women on metformin for diabetes or other indications among those seeking teratology information services. ( Amar, E; Baud, D; Beau-Salinas, F; Bernard, N; Buclin, T; Cassina, M; Csajka, C; Dautriche, A; De Santis, M; Duman, MK; Dunstan, H; Eleftheriou, G; Hernandez-Diaz, S; Kaplan, YC; Klinger, G; Maňáková, E; Panchaud, A; Passier, A; Pistelli, A; Rothuizen, LE; Rousson, V; Vial, T; Winterfeld, U, 2018) |
| "The aim of this study was to evaluate the risk of major birth defects and spontaneous abortion after metformin use during the first trimester of pregnancy." | 3.88 | Pregnancy outcome after first-trimester exposure to metformin: A prospective cohort study. ( Beck, E; Grupe, K; Schaefer, C; Scherneck, S; Schlinke, N; Weber-Schoendorfer, C, 2018) |
| "There were 56 patients who received metformin during pregnancy (metformin group) compared with 50 patients who did not receive the treatment (control group)." | 3.81 | Effect of metformin on early pregnancy loss in women with polycystic ovary syndrome. ( Al-Biate, MA, 2015) |
| " There is no evidence-based schema for achieving pregnancy in women with PCOS, though lifestyle modification, clomiphene citrate, and metformin are the current front line therapies." | 3.74 | Pregnancy considerations in women with polycystic ovary syndrome. ( Legro, RS, 2007) |
| "In women with polycystic ovary syndrome, metformin administration, not laparoscopic ovarian drilling, reduces plasminogen activator inhibitor 1 (PAI-1) activity." | 3.73 | Plasminogen activator inhibitor 1 and miscarriage after metformin treatment and laparoscopic ovarian drilling in patients with polycystic ovary syndrome. ( Falbo, A; Orio, F; Palomba, S; Russo, T; Tolino, A; Zullo, F, 2005) |
| "Metformin therapy during pregnancy in women with PCOS was safely associated with reduction in SAB and in GD, was not teratogenic, and did not adversely affect birthweight or height, or height, weight, and motor and social development at 3 and 6 months of life." | 3.71 | Pregnancy outcomes among women with polycystic ovary syndrome treated with metformin. ( Glueck, CJ; Goldenberg, N; Sieve-Smith, L; Wang, P, 2002) |
| "To evaluate the risk of miscarriage in IVF cycles in women with PCOS." | 3.01 | Polycystic ovarian syndrome and miscarriage in IVF: systematic revision of the literature and meta-analysis. ( Díaz-Nuñez, M; Laínz, L; Matorras, R; Moreira, D; Pérez-Fernandez, S; Pijoan, JI; Sainz, H, 2023) |
| "Metformin has no significant effect on birthweight percentile in obese pregnant women." | 2.80 | Effect of metformin on maternal and fetal outcomes in obese pregnant women (EMPOWaR): a randomised, double-blind, placebo-controlled trial. ( Chiswick, C; Denison, F; Drake, AJ; Forbes, S; Lashen, H; Murray, G; Newby, DE; Norman, JE; Quenby, S; Reynolds, RM; Rodriguez, A; Walker, BR; Weeks, A; Whyte, S; Wray, S, 2015) |
| " No adverse maternal-fetal side effects were reported on enoxaparin alone or enoxaparin-metformin." | 2.74 | Enoxaparin-metformin and enoxaparin alone may safely reduce pregnancy loss. ( Glueck, CJ; Goldenberg, N; Khan, N; Ramidi, G; Wang, P, 2009) |
| "When metformin was compared with CC, data for live birth were inconclusive, and the findings were limited by lack of evidence." | 2.61 | Metformin for ovulation induction (excluding gonadotrophins) in women with polycystic ovary syndrome. ( Balen, AH; Morley, LC; Norman, RJ; Sharpe, A; Tang, T, 2019) |
| "Polycystic ovary syndrome is characterized among other things by oligo-amenorrhea and may account for more than 75% of cases with anoluvatory infertility." | 2.43 | Is metformin therapy for polycystic ovary syndrome safe during pregnancy? ( Brock, B; Ovesen, P; Rungby, J; Schmitz, O; Smidt, K, 2005) |
| "Insulin resistance is a central feature of polycystic ovary syndrome (PCOS)." | 2.42 | Should insulin-sensitizing drugs be used in the treatment of polycystic ovary syndrome? ( Cheang, KI; Nestler, JE, 2004) |
| "Polycystic ovary syndrome is the most common form of female infertility in the United States." | 1.31 | Effects of metformin on early pregnancy loss in the polycystic ovary syndrome. ( Iuorno, MJ; Jakubowicz, DJ; Jakubowicz, S; Nestler, JE; Roberts, KA, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 17 (33.33) | 29.6817 |
| 2010's | 26 (50.98) | 24.3611 |
| 2020's | 8 (15.69) | 2.80 |
| Authors | Studies |
|---|---|
| Espnes, KA | 1 |
| Hønnås, A | 1 |
| Løvvik, TS | 3 |
| Gundersen, POM | 1 |
| Naavik, A | 1 |
| Skogvoll, E | 1 |
| Westin, AA | 1 |
| Spigset, O | 1 |
| Vanky, E | 3 |
| Zhao, Q | 1 |
| He, J | 1 |
| Matorras, R | 1 |
| Pijoan, JI | 1 |
| Laínz, L | 1 |
| Díaz-Nuñez, M | 1 |
| Sainz, H | 1 |
| Pérez-Fernandez, S | 1 |
| Moreira, D | 1 |
| Peng, G | 1 |
| Yan, Z | 1 |
| Liu, Y | 1 |
| Li, J | 1 |
| Ma, J | 1 |
| Tong, N | 1 |
| Wang, Y | 4 |
| Ryssdal, M | 1 |
| Stokkeland, LMT | 1 |
| Jarmund, AH | 1 |
| Steinkjer, B | 1 |
| Madssen, TS | 1 |
| Iversen, AC | 1 |
| Giskeødegård, GF | 1 |
| Tosti, G | 1 |
| Barberio, A | 1 |
| Tartaglione, L | 1 |
| Rizzi, A | 1 |
| Di Leo, M | 1 |
| Viti, L | 1 |
| Sirico, A | 1 |
| De Carolis, S | 1 |
| Pontecorvi, A | 1 |
| Lanzone, A | 1 |
| Pitocco, D | 1 |
| Sharpe, A | 1 |
| Morley, LC | 2 |
| Tang, T | 2 |
| Norman, RJ | 3 |
| Balen, AH | 2 |
| Taghavi, SA | 1 |
| van Wely, M | 1 |
| Jahanfar, S | 1 |
| Bazarganipour, F | 1 |
| Yasmin, E | 1 |
| Panchaud, A | 1 |
| Rousson, V | 1 |
| Vial, T | 1 |
| Bernard, N | 1 |
| Baud, D | 1 |
| Amar, E | 1 |
| De Santis, M | 1 |
| Pistelli, A | 1 |
| Dautriche, A | 1 |
| Beau-Salinas, F | 1 |
| Cassina, M | 1 |
| Dunstan, H | 1 |
| Passier, A | 1 |
| Kaplan, YC | 1 |
| Duman, MK | 1 |
| Maňáková, E | 1 |
| Eleftheriou, G | 1 |
| Klinger, G | 1 |
| Winterfeld, U | 1 |
| Rothuizen, LE | 1 |
| Buclin, T | 1 |
| Csajka, C | 1 |
| Hernandez-Diaz, S | 1 |
| Puscheck, EE | 1 |
| Bolnick, A | 1 |
| Awonuga, A | 1 |
| Yang, Y | 1 |
| Abdulhasan, M | 1 |
| Li, Q | 1 |
| Secor, E | 1 |
| Louden, E | 1 |
| Hüttemann, M | 1 |
| Rappolee, DA | 1 |
| Scherneck, S | 1 |
| Schlinke, N | 1 |
| Beck, E | 1 |
| Grupe, K | 1 |
| Weber-Schoendorfer, C | 1 |
| Schaefer, C | 1 |
| Showell, MG | 1 |
| Mackenzie-Proctor, R | 1 |
| Jordan, V | 1 |
| Hodgson, R | 1 |
| Farquhar, C | 1 |
| Egan, AM | 1 |
| Brassill, MJ | 1 |
| Brosnan, E | 1 |
| Carmody, L | 1 |
| Clarke, H | 1 |
| Coogan Kelly, C | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Metformin on Healthy Live Birth After In-vitro Fertilization in Women With Prediabetes Mellitus: a Multicenter Double-blind Placebo Controlled Randomized Trial[NCT06064669] | 988 participants (Anticipated) | Interventional | 2023-10-01 | Not yet recruiting | |||
| Abnormalities of the Endometrium Persist Despite Adequate Progesterone Supplementation in the Polycystic Ovary Syndrome[NCT05062135] | 36 participants (Actual) | Interventional | 2014-02-10 | Completed | |||
| Independent and Additive Effects Of Micronutrients With Metformin In Patients With PCOS:A Double Blind Randomized Placebo Controlled Trial[NCT05653895] | 250 participants (Anticipated) | Interventional | 2022-12-07 | Recruiting | |||
| The Effects of Acetyl L--Carnitine and Myo/Chiro-Inositol on Improving Ovulation, Pregnancy Rate, Ovarian Function and Perceived Stress Response in Patients With PCOS[NCT05767515] | 120 participants (Anticipated) | Interventional | 2023-04-15 | Not yet recruiting | |||
| A Prospective, Randomized, Double-blind, Multi-centre Study, Where the Possible Effect of Metformin to Prevent Late Miscarriage and Preterm Delivery is Studied in Women With Polycystic Ovary Syndrome (PCOS)[NCT01587378] | 489 participants (Actual) | Interventional | 2012-10-31 | Completed | |||
| Prevention of Pre-eclampsia Using Metformin: a Randomized Control Trial[NCT04855513] | 414 participants (Anticipated) | Interventional | 2022-03-24 | Not yet recruiting | |||
| Aspirin Versus Metformin in Pregnancies at High Risk of Preterm Preeclampsia: a 3-arm Randomized Controlled Trial[NCT05580523] | 3,000 participants (Anticipated) | Interventional | 2023-07-03 | Recruiting | |||
| A Multi-center, Prospective, Cohort Study to Elucidate the Effects of Metformin Treatment on Steroid Hormones and Social Behavior. Linking Autistic Behaviorial Symptoms to Changes in Steroid Hormone Availability[NCT04930471] | 45 participants (Anticipated) | Observational | 2021-06-30 | Not yet recruiting | |||
| Preventing Recurrent Gestational Diabetes Mellitus With Early Metformin Intervention[NCT02394158] | Phase 4 | 112 participants (Anticipated) | Interventional | 2015-01-27 | Recruiting | ||
| Is the Co-administration of Metformine and CC as Compared to Placebo and CC Superior to Induce Ovulation in PCOS Patients With a Confirmed insulin-resistant-a Double Blind Randomized Clinical Trial[NCT02523898] | Phase 2 | 388 participants (Anticipated) | Interventional | 2015-11-30 | Enrolling by invitation | ||
| Effects of Metformin on Fertility and Pregnancy in Women With Polycystic Ovary Syndrome: a Randomized, Prospective, Placebo-controlled Multicenter Study[NCT00994812] | Phase 3 | 326 participants (Actual) | Interventional | 2002-08-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
24 reviews available for metformin and Abortion, Spontaneous
| Article | Year |
|---|---|
Efficacy and safety of metformin in pregnant women with polycystic ovary syndrome: a systematic review with meta-analysis of randomized and non-randomized controlled trials.
Topics: Abortion, Spontaneous; Clinical Trials as Topic; Female; Humans; Hypoglycemic Agents; Infant, Newbor | 2022 |
Polycystic ovarian syndrome and miscarriage in IVF: systematic revision of the literature and meta-analysis.
Topics: Abortion, Spontaneous; Female; Fertilization in Vitro; Humans; Metformin; Polycystic Ovary Syndrome; | 2023 |
The effects of first-line pharmacological treatments for reproductive outcomes in infertile women with PCOS: a systematic review and network meta-analysis.
Topics: Abortion, Spontaneous; Clomiphene; Female; Humans; Infertility, Female; Live Birth; Metformin; Netwo | 2023 |
Lights and shadows on the use of metformin in pregnancy: from the preconception phase to breastfeeding and beyond.
Topics: Abortion, Spontaneous; Breast Feeding; Diabetes Mellitus, Type 2; Diabetes, Gestational; Female; Hum | 2023 |
Metformin for ovulation induction (excluding gonadotrophins) in women with polycystic ovary syndrome.
Topics: Abortion, Spontaneous; Birth Rate; Body Mass Index; Clomiphene; Female; Fertility Agents, Female; Hu | 2019 |
Metformin for ovulation induction (excluding gonadotrophins) in women with polycystic ovary syndrome.
Topics: Abortion, Spontaneous; Birth Rate; Body Mass Index; Clomiphene; Female; Fertility Agents, Female; Hu | 2019 |
Metformin for ovulation induction (excluding gonadotrophins) in women with polycystic ovary syndrome.
Topics: Abortion, Spontaneous; Birth Rate; Body Mass Index; Clomiphene; Female; Fertility Agents, Female; Hu | 2019 |
Metformin for ovulation induction (excluding gonadotrophins) in women with polycystic ovary syndrome.
Topics: Abortion, Spontaneous; Birth Rate; Body Mass Index; Clomiphene; Female; Fertility Agents, Female; Hu | 2019 |
Pharmacological and non-pharmacological strategies for obese women with subfertility.
Topics: Abortion, Spontaneous; Appetite Depressants; Bias; Carnitine; Clomiphene; Dexfenfluramine; Drug Ther | 2021 |
Insulin-sensitising drugs (metformin, rosiglitazone, pioglitazone, D-chiro-inositol) for women with polycystic ovary syndrome, oligo amenorrhoea and subfertility.
Topics: Abortion, Spontaneous; Anovulation; Clomiphene; Female; Humans; Hypoglycemic Agents; Infertility, Fe | 2017 |
Insulin-sensitising drugs (metformin, rosiglitazone, pioglitazone, D-chiro-inositol) for women with polycystic ovary syndrome, oligo amenorrhoea and subfertility.
Topics: Abortion, Spontaneous; Anovulation; Clomiphene; Female; Humans; Hypoglycemic Agents; Infertility, Fe | 2017 |
Insulin-sensitising drugs (metformin, rosiglitazone, pioglitazone, D-chiro-inositol) for women with polycystic ovary syndrome, oligo amenorrhoea and subfertility.
Topics: Abortion, Spontaneous; Anovulation; Clomiphene; Female; Humans; Hypoglycemic Agents; Infertility, Fe | 2017 |
Insulin-sensitising drugs (metformin, rosiglitazone, pioglitazone, D-chiro-inositol) for women with polycystic ovary syndrome, oligo amenorrhoea and subfertility.
Topics: Abortion, Spontaneous; Anovulation; Clomiphene; Female; Humans; Hypoglycemic Agents; Infertility, Fe | 2017 |
Why AMPK agonists not known to be stressors may surprisingly contribute to miscarriage or hinder IVF/ART.
Topics: Abortion, Spontaneous; Adenosine Triphosphate; AMP-Activated Protein Kinase Kinases; Blastocyst; Die | 2018 |
Inositol for subfertile women with polycystic ovary syndrome.
Topics: Abortion, Spontaneous; Administration, Oral; Birth Rate; Clomiphene; Combined Modality Therapy; Fema | 2018 |
Diverse roles of metformin during peri-implantation development: revisiting novel molecular mechanisms underlying clinical implications.
Topics: Abortion, Spontaneous; AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Embryo I | 2013 |
A systematic review and meta-analysis of metformin among patients with polycystic ovary syndrome undergoing assisted reproductive technology procedures.
Topics: Abortion, Spontaneous; Adult; Female; Humans; Hypoglycemic Agents; Live Birth; Metformin; Ovarian Hy | 2015 |
Efficacy of metformin on pregnancy complications in women with polycystic ovary syndrome: a meta-analysis.
Topics: Abortion, Spontaneous; Case-Control Studies; Diabetes, Gestational; Female; Humans; Hypoglycemic Age | 2015 |
Effect of metformin treatment during pregnancy on women with PCOS: a systematic review and meta-analysis.
Topics: Abortion, Spontaneous; Birth Weight; Diabetes, Gestational; Evidence-Based Medicine; Female; Humans; | 2016 |
Effect of metformin treatment during pregnancy on women with PCOS: a systematic review and meta-analysis.
Topics: Abortion, Spontaneous; Birth Weight; Diabetes, Gestational; Evidence-Based Medicine; Female; Humans; | 2016 |
Effect of metformin treatment during pregnancy on women with PCOS: a systematic review and meta-analysis.
Topics: Abortion, Spontaneous; Birth Weight; Diabetes, Gestational; Evidence-Based Medicine; Female; Humans; | 2016 |
Effect of metformin treatment during pregnancy on women with PCOS: a systematic review and meta-analysis.
Topics: Abortion, Spontaneous; Birth Weight; Diabetes, Gestational; Evidence-Based Medicine; Female; Humans; | 2016 |
Effect of preconceptional metformin on abortion risk in polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trials.
Topics: Abortion, Spontaneous; Adult; Algorithms; Female; Humans; Hypoglycemic Agents; Metformin; Ovulation | 2009 |
Pregnancy outcomes and the effect of metformin treatment in women with polycystic ovary syndrome: an overview.
Topics: Abortion, Spontaneous; Diabetes, Gestational; Female; Humans; Hyperandrogenism; Hyperinsulinism; Hyp | 2012 |
The effectiveness of metformin ovulation induction treatment in patients with PCOS: a systematic review and meta-analysis.
Topics: Abortion, Spontaneous; Clomiphene; Drug Therapy, Combination; Estrogen Antagonists; Evidence-Based M | 2012 |
Reproductive impact of polycystic ovary syndrome.
Topics: Abortion, Spontaneous; Clomiphene; Female; Fertilization in Vitro; Humans; Infant, Newborn; Infertil | 2012 |
Effects of metformin in women with polycystic ovary syndrome treated with gonadotrophins for in vitro fertilisation and intracytoplasmic sperm injection cycles: a systematic review and meta-analysis of randomised controlled trials.
Topics: Abortion, Spontaneous; Dinoprostone; Embryo Implantation; Female; Fertility Agents, Female; Fertiliz | 2013 |
Should patients with polycystic ovarian syndrome be treated with metformin?
Topics: Abortion, Spontaneous; Cardiovascular Diseases; Diabetes Mellitus; Female; Humans; Hypoglycemic Agen | 2002 |
Metformin in obstetric and gynecologic practice: a review.
Topics: Abortion, Spontaneous; Anovulation; Diabetes Mellitus, Type 2; Female; Gastrointestinal Tract; Human | 2004 |
Should we continue or stop insulin sensitizing drugs during pregnancy?
Topics: Abortion, Spontaneous; Diabetes, Gestational; Female; Humans; Hypoglycemic Agents; Metformin; Polycy | 2004 |
Should insulin-sensitizing drugs be used in the treatment of polycystic ovary syndrome?
Topics: Abortion, Spontaneous; Anovulation; Clomiphene; Drug Therapy, Combination; Female; Humans; Hypoglyce | 2004 |
Is metformin therapy for polycystic ovary syndrome safe during pregnancy?
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Anencephaly; Animals; Anophthalmos; Blastocyst; | 2005 |
Pregnancy complications in PCOS.
Topics: Abortion, Spontaneous; Diabetes, Gestational; Female; Humans; Hyperinsulinism; Hypertension, Pregnan | 2006 |
12 trials available for metformin and Abortion, Spontaneous
| Article | Year |
|---|---|
Use of metformin to treat pregnant women with polycystic ovary syndrome (PregMet2): a randomised, double-blind, placebo-controlled trial.
Topics: Abortion, Spontaneous; Adolescent; Adult; Biomarkers; Blood Glucose; Diabetes, Gestational; Double-B | 2019 |
Use of metformin to treat pregnant women with polycystic ovary syndrome (PregMet2): a randomised, double-blind, placebo-controlled trial.
Topics: Abortion, Spontaneous; Adolescent; Adult; Biomarkers; Blood Glucose; Diabetes, Gestational; Double-B | 2019 |
Use of metformin to treat pregnant women with polycystic ovary syndrome (PregMet2): a randomised, double-blind, placebo-controlled trial.
Topics: Abortion, Spontaneous; Adolescent; Adult; Biomarkers; Blood Glucose; Diabetes, Gestational; Double-B | 2019 |
Use of metformin to treat pregnant women with polycystic ovary syndrome (PregMet2): a randomised, double-blind, placebo-controlled trial.
Topics: Abortion, Spontaneous; Adolescent; Adult; Biomarkers; Blood Glucose; Diabetes, Gestational; Double-B | 2019 |
Effect of metformin on maternal and fetal outcomes in obese pregnant women (EMPOWaR): a randomised, double-blind, placebo-controlled trial.
Topics: Abortion, Spontaneous; Adult; Diabetes, Gestational; Double-Blind Method; Female; Fetal Macrosomia; | 2015 |
Effect of metformin on maternal and fetal outcomes in obese pregnant women (EMPOWaR): a randomised, double-blind, placebo-controlled trial.
Topics: Abortion, Spontaneous; Adult; Diabetes, Gestational; Double-Blind Method; Female; Fetal Macrosomia; | 2015 |
Effect of metformin on maternal and fetal outcomes in obese pregnant women (EMPOWaR): a randomised, double-blind, placebo-controlled trial.
Topics: Abortion, Spontaneous; Adult; Diabetes, Gestational; Double-Blind Method; Female; Fetal Macrosomia; | 2015 |
Effect of metformin on maternal and fetal outcomes in obese pregnant women (EMPOWaR): a randomised, double-blind, placebo-controlled trial.
Topics: Abortion, Spontaneous; Adult; Diabetes, Gestational; Double-Blind Method; Female; Fetal Macrosomia; | 2015 |
Effect of metformin on maternal and fetal outcomes in obese pregnant women (EMPOWaR): a randomised, double-blind, placebo-controlled trial.
Topics: Abortion, Spontaneous; Adult; Diabetes, Gestational; Double-Blind Method; Female; Fetal Macrosomia; | 2015 |
Effect of metformin on maternal and fetal outcomes in obese pregnant women (EMPOWaR): a randomised, double-blind, placebo-controlled trial.
Topics: Abortion, Spontaneous; Adult; Diabetes, Gestational; Double-Blind Method; Female; Fetal Macrosomia; | 2015 |
Effect of metformin on maternal and fetal outcomes in obese pregnant women (EMPOWaR): a randomised, double-blind, placebo-controlled trial.
Topics: Abortion, Spontaneous; Adult; Diabetes, Gestational; Double-Blind Method; Female; Fetal Macrosomia; | 2015 |
Effect of metformin on maternal and fetal outcomes in obese pregnant women (EMPOWaR): a randomised, double-blind, placebo-controlled trial.
Topics: Abortion, Spontaneous; Adult; Diabetes, Gestational; Double-Blind Method; Female; Fetal Macrosomia; | 2015 |
Effect of metformin on maternal and fetal outcomes in obese pregnant women (EMPOWaR): a randomised, double-blind, placebo-controlled trial.
Topics: Abortion, Spontaneous; Adult; Diabetes, Gestational; Double-Blind Method; Female; Fetal Macrosomia; | 2015 |
Enoxaparin-metformin and enoxaparin alone may safely reduce pregnancy loss.
Topics: Abortion, Habitual; Abortion, Spontaneous; Adult; Anticoagulants; Blood Coagulation Disorders; Dose- | 2009 |
Laparoscopic ovarian diathermy vs clomiphene citrate plus metformin as second-line strategy for infertile anovulatory patients with polycystic ovary syndrome: a randomized controlled trial.
Topics: Abortion, Spontaneous; Anovulation; Body Mass Index; Clomiphene; Diathermy; Drug Therapy, Combinatio | 2010 |
Effect of metformin on miscarriage in pregnant patients with polycystic ovary syndrome.
Topics: Abortion, Spontaneous; Adult; Drug Administration Schedule; Female; Humans; Hypoglycemic Agents; Met | 2009 |
N-acetyl cysteine plus clomiphene citrate versus metformin and clomiphene citrate in treatment of clomiphene-resistant polycystic ovary syndrome: a randomized controlled trial.
Topics: Abortion, Spontaneous; Acetylcysteine; Adult; Clomiphene; Drug Resistance; Drug Therapy, Combination | 2010 |
The administration of metformin during pregnancy reduces polycystic ovary syndrome related gestational complications.
Topics: Abortion, Spontaneous; Adult; Blood Glucose; Diabetes, Gestational; Female; Humans; Hyperinsulinism; | 2011 |
The administration of metformin during pregnancy reduces polycystic ovary syndrome related gestational complications.
Topics: Abortion, Spontaneous; Adult; Blood Glucose; Diabetes, Gestational; Female; Humans; Hyperinsulinism; | 2011 |
The administration of metformin during pregnancy reduces polycystic ovary syndrome related gestational complications.
Topics: Abortion, Spontaneous; Adult; Blood Glucose; Diabetes, Gestational; Female; Humans; Hyperinsulinism; | 2011 |
The administration of metformin during pregnancy reduces polycystic ovary syndrome related gestational complications.
Topics: Abortion, Spontaneous; Adult; Blood Glucose; Diabetes, Gestational; Female; Humans; Hyperinsulinism; | 2011 |
Metformin improves pregnancy and live-birth rates in women with polycystic ovary syndrome (PCOS): a multicenter, double-blind, placebo-controlled randomized trial.
Topics: Abortion, Spontaneous; Adult; Birth Rate; Double-Blind Method; Female; Humans; Infertility, Female; | 2012 |
Effects of metformin-diet intervention before and throughout pregnancy on obstetric and neonatal outcomes in patients with polycystic ovary syndrome.
Topics: Abortion, Spontaneous; Adult; Diabetes, Gestational; Female; Fetal Macrosomia; Humans; Hypoglycemic | 2013 |
Pregnancy loss, polycystic ovary syndrome, thrombophilia, hypofibrinolysis, enoxaparin, metformin.
Topics: Abortion, Habitual; Abortion, Spontaneous; Adult; Blood Coagulation Disorders; Case-Control Studies; | 2004 |
Metformin reduces abortion in pregnant women with polycystic ovary syndrome.
Topics: Abortion, Spontaneous; Adult; Female; Humans; Hypoglycemic Agents; Metformin; Polycystic Ovary Syndr | 2006 |
Continuing metformin throughout pregnancy in women with polycystic ovary syndrome appears to safely reduce first-trimester spontaneous abortion: a pilot study.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Adult; Birth Weight; Female; Health Status Indic | 2001 |
15 other studies available for metformin and Abortion, Spontaneous
| Article | Year |
|---|---|
Metformin serum concentrations during pregnancy and post partum - A clinical study in patients with polycystic ovary syndrome.
Topics: Abortion, Spontaneous; Female; Humans; Hypoglycemic Agents; Infant, Newborn; Metformin; Polycystic O | 2022 |
Immunomodulatory Effects of Metformin Treatment in Pregnant Women With PCOS.
Topics: Abortion, Spontaneous; Cytokines; Female; Humans; Hypoglycemic Agents; Infant, Newborn; Metformin; P | 2023 |
Pregnancy outcomes in women on metformin for diabetes or other indications among those seeking teratology information services.
Topics: Abortion, Spontaneous; Adult; Cohort Studies; Female; Humans; Hypoglycemic Agents; Metformin; Pregna | 2018 |
Pregnancy outcome after first-trimester exposure to metformin: A prospective cohort study.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Adolescent; Adult; Diabetes Mellitus, Type 2; Fe | 2018 |
An Irish National Diabetes in Pregnancy Audit: aiming for best outcomes for women with diabetes.
Topics: Abortion, Spontaneous; Adult; Aspirin; Cesarean Section; Clinical Audit; Delivery of Health Care; De | 2020 |
The globular heads of the C1q receptor regulate apoptosis in human extravillous cytotrophoblast-derived transformed cells via a mitochondria-dependent pathway.
Topics: Abortion, Spontaneous; Apoptosis; Calcium; Cell Line, Transformed; Chorionic Villi; Cytosol; Female; | 2014 |
Metformin use in patients undergoing in vitro fertilization treatment: results of a worldwide web-based survey.
Topics: Abortion, Spontaneous; Female; Fertilization in Vitro; Humans; Hypoglycemic Agents; Insulin Resistan | 2015 |
Exploring the significance of sex hormone-binding globulin examination in the treament of women with polycystic ovarian syndrome (PCOS).
Topics: Abortion, Spontaneous; Adult; Androgen Antagonists; Blood Glucose; Body Mass Index; Clomiphene; Cypr | 2015 |
Effect of metformin on early pregnancy loss in women with polycystic ovary syndrome.
Topics: Abortion, Spontaneous; Adult; Female; Humans; Hypoglycemic Agents; Metformin; Polycystic Ovary Syndr | 2015 |
A challenge in the management of women with polycystic ovary syndrome.
Topics: Abortion, Spontaneous; Anti-Mullerian Hormone; Female; Ferritins; Humans; Hypoglycemic Agents; Insul | 2016 |
Pregnancy outcomes among women with polycystic ovary syndrome treated with metformin.
Topics: Abortion, Spontaneous; Birth Weight; Body Height; Child Development; Female; Follow-Up Studies; Huma | 2002 |
Plasminogen activator inhibitor 1 and miscarriage after metformin treatment and laparoscopic ovarian drilling in patients with polycystic ovary syndrome.
Topics: Abortion, Spontaneous; Female; Humans; Laparoscopy; Metformin; Ovary; Plasminogen Activator Inhibito | 2005 |
Plasminogen activator inhibitor activity, 4G5G polymorphism of the plasminogen activator inhibitor 1 gene, and first-trimester miscarriage in women with polycystic ovary syndrome.
Topics: Abortion, Spontaneous; Body Mass Index; Case-Control Studies; Female; Genotype; Humans; Insulin Resi | 2006 |
Pregnancy considerations in women with polycystic ovary syndrome.
Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema | 2007 |
Effects of metformin on early pregnancy loss in the polycystic ovary syndrome.
Topics: Abortion, Spontaneous; Adult; Androgens; Blood Glucose; Female; Humans; Hypoglycemic Agents; Insulin | 2002 |