metaraminol has been researched along with Pregnancy in 45 studies
Metaraminol: A sympathomimetic agent that acts predominantly at alpha-1 adrenergic receptors. It has been used primarily as a vasoconstrictor in the treatment of HYPOTENSION.
metaraminol : A member of the class of phenylethanolamines that is 2-amino-1-phenylethanol substituted by a methyl group at position 2 and a phenolic hydroxy group at position 1. A sympathomimetic agent , it is used in the treatment of hypotension.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A direct comparison of phenylephrine, metaraminol, and norepinephrine in preventing hypotension during spinal anaesthesia for elective caesarean section has never been made." | 9.51 | Comparison of Metaraminol, Phenylephrine, and Norepinephrine Infusion for Prevention of Hypotension During Combined Spinal-Epidural Anaesthesia for Elective Caesarean Section: A Three-Arm, Randomized, Double-Blind, Non-Inferiority Trial. ( Chen, G; Chu, M; Yu, X; Yu, Y; Zhang, Y; Zhou, Y, 2022) |
| "A direct comparison of phenylephrine, metaraminol, and norepinephrine in preventing hypotension during spinal anaesthesia for elective caesarean section has never been made." | 5.51 | Comparison of Metaraminol, Phenylephrine, and Norepinephrine Infusion for Prevention of Hypotension During Combined Spinal-Epidural Anaesthesia for Elective Caesarean Section: A Three-Arm, Randomized, Double-Blind, Non-Inferiority Trial. ( Chen, G; Chu, M; Yu, X; Yu, Y; Zhang, Y; Zhou, Y, 2022) |
| " The total dose of metaraminol required until uterine incision was similar in multiple gestation pregnancy (median 2." | 3.74 | A prospective comparison of vasopressor requirement and hemodynamic changes during spinal anesthesia for cesarean delivery in patients with multiple gestation versus singleton pregnancy. ( Critchley, LA; Gin, T; Karmakar, MK; Khaw, KS; Ng, FF; Ngan Kee, WD, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 28 (62.22) | 18.7374 |
| 1990's | 3 (6.67) | 18.2507 |
| 2000's | 6 (13.33) | 29.6817 |
| 2010's | 4 (8.89) | 24.3611 |
| 2020's | 4 (8.89) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, T | 2 |
| Gao, X | 1 |
| Zou, S | 2 |
| Xu, C | 2 |
| Wang, M | 1 |
| Niu, Z | 1 |
| Guo, L | 1 |
| Shi, Z | 1 |
| Zhang, J | 1 |
| Qi, D | 1 |
| Zhou, Y | 1 |
| Yu, Y | 1 |
| Chu, M | 1 |
| Zhang, Y | 1 |
| Yu, X | 1 |
| Chen, G | 1 |
| Cheng, Z | 1 |
| Pan, S | 1 |
| Zeng, H | 1 |
| Shan, Y | 1 |
| Feng, Y | 1 |
| Zhang, H | 1 |
| Patel, S | 3 |
| Chao, E | 1 |
| Sun, HL | 1 |
| Huang, SW | 1 |
| Liao, JH | 1 |
| Ma, PL | 1 |
| Chen, HC | 1 |
| McDonnell, NJ | 1 |
| Paech, MJ | 1 |
| Muchatuta, NA | 1 |
| Hillyard, S | 1 |
| Nathan, EA | 1 |
| Ngan Kee, WD | 4 |
| Bannard-Smith, J | 1 |
| Yuill, G | 1 |
| Washington, SJ | 1 |
| Yamaguchi, ET | 1 |
| Cardoso, MM | 1 |
| Torres, ML | 1 |
| Nascimento, RC | 1 |
| Ribeiro, MC | 1 |
| Frerichs, E | 1 |
| Payen, D | 1 |
| BOOKRAJIAN, EN | 1 |
| LEFEVRE, H | 1 |
| NIELSEN, B | 1 |
| PEDERSEN, LM | 1 |
| MULLER, DA | 1 |
| DEJONG, RH | 1 |
| MANESCHI, M | 1 |
| ALBANO, SB | 1 |
| Yuen, MK | 1 |
| Key, LK | 1 |
| Khaw, KS | 3 |
| Ng, FF | 2 |
| Karmakar, MK | 1 |
| Critchley, LA | 1 |
| Gin, T | 1 |
| Bernstein, A | 1 |
| Li, P | 1 |
| Tong, C | 2 |
| Eisenach, JC | 2 |
| Chikermane, Y | 1 |
| Alexander, R | 1 |
| Lau, TK | 1 |
| Lee, BB | 2 |
| Wong, MM | 1 |
| Anderson, TR | 2 |
| Slotkin, TA | 2 |
| Jeyamalar, R | 1 |
| Sivanesaratnam, V | 1 |
| Kuppuvelumani, P | 1 |
| Cavanagh, D | 2 |
| Dahm, CH | 1 |
| Pritchard, JA | 1 |
| Whalley, PJ | 1 |
| Levinson, G | 1 |
| Shnider, SM | 3 |
| Hill, PM | 1 |
| Young, M | 2 |
| Van Nimwegen, D | 1 |
| Dyer, DC | 1 |
| Wadhwa, RK | 1 |
| Wadhwa, SR | 1 |
| Khurana, RC | 1 |
| Ralston, DH | 1 |
| DeLorimier, AA | 1 |
| Joseph, AA | 1 |
| Kincl, FA | 1 |
| Triggle, CR | 1 |
| Reiffenstein, RJ | 1 |
| Martinez, JT | 1 |
| Fernandez, G | 1 |
| Vazquez-Leon, H | 1 |
| James, FM | 1 |
| Greiss, FC | 1 |
| Kemp, RA | 1 |
| de Lorimier, AA | 1 |
| Steffenson, JL | 1 |
| Hopins, L | 1 |
| Reynolds, ML | 1 |
| Brienza, A | 1 |
| De Leonardis, A | 1 |
| Wolfson, B | 1 |
| Lucas, W | 1 |
| Kirschbaum, T | 1 |
| Assali, NS | 2 |
| Speroff, L | 1 |
| McLeod, AG | 1 |
| Lucas, WE | 1 |
| Kirschbaum, TH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Glycopyrrolate on Vasopressors Requirement for Non-elective Caesarean Section Under Spinal Anaesthesia[NCT04401345] | Phase 4 | 258 participants (Actual) | Interventional | 2020-06-01 | Completed | ||
| Randomized, Double-blind, Controlled Clinical Trial for Comparison of Continuous Phenylephrine Versus Norepinephrine Infusion for Maintenance of Hemodynamic Stability During Cesarean Section Under Spinal Anesthesia[NCT03849508] | Phase 4 | 124 participants (Actual) | Interventional | 2019-02-27 | Completed | ||
| Up-Down Determination of the ED90 of Metaraminol to Treat Hypotension During Elective Cesarean Section[NCT01108874] | Phase 2 | 48 participants (Anticipated) | Interventional | 2009-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for metaraminol and Pregnancy
| Article | Year |
|---|---|
Cardiovascular Drug Administration Errors During Neuraxial Anesthesia or Analgesia-A Narrative Review.
Topics: Analgesia, Epidural; Anesthesia, Epidural; Anesthesia, Spinal; Cardiovascular Agents; Digoxin; Dopam | 2023 |
Cardiovascular Drug Administration Errors During Neuraxial Anesthesia or Analgesia-A Narrative Review.
Topics: Analgesia, Epidural; Anesthesia, Epidural; Anesthesia, Spinal; Cardiovascular Agents; Digoxin; Dopam | 2023 |
Cardiovascular Drug Administration Errors During Neuraxial Anesthesia or Analgesia-A Narrative Review.
Topics: Analgesia, Epidural; Anesthesia, Epidural; Anesthesia, Spinal; Cardiovascular Agents; Digoxin; Dopam | 2023 |
Cardiovascular Drug Administration Errors During Neuraxial Anesthesia or Analgesia-A Narrative Review.
Topics: Analgesia, Epidural; Anesthesia, Epidural; Anesthesia, Spinal; Cardiovascular Agents; Digoxin; Dopam | 2023 |
Metaraminol use during spinal anaesthesia for caesarean section: a meta-analysis of randomised controlled trials.
Topics: Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Cesarean Section; Female; Humans; Hydrogen-Ion C | 2019 |
The use of vasopressors during spinal anaesthesia for caesarean section.
Topics: Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Cardiac Output; Cesarean Section; Dose-Response | 2017 |
Vasopressors in obstetrics.
Topics: Angiotensin II; Drug Synergism; Ephedrine; Epinephrine; Female; Humans; Hypotension; Isoproterenol; | 1974 |
9 trials available for metaraminol and Pregnancy
| Article | Year |
|---|---|
Randomised double-blind dose-response study of weight-adjusted infusions of metaraminol for preventing hypotension with combined spinal-epidural anaesthesia for elective Caesarean delivery in the supine position.
Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthesia, Spinal; Cesarean Section; Dose-Res | 2022 |
Comparison of Metaraminol, Phenylephrine, and Norepinephrine Infusion for Prevention of Hypotension During Combined Spinal-Epidural Anaesthesia for Elective Caesarean Section: A Three-Arm, Randomized, Double-Blind, Non-Inferiority Trial.
Topics: Adult; Anesthesia, Epidural; Anesthesia, Spinal; Cesarean Section; Double-Blind Method; Female; Huma | 2022 |
Effect of Weight-Adjusted Phenylephrine, Norepinephrine, and Metaraminol for Elective Cesarean Delivery on Neonatal Acid-Base Status: A Randomized Controlled Trial.
Topics: Anesthesia, Spinal; Cesarean Section; Double-Blind Method; Female; Humans; Hypotension; Infant, Newb | 2022 |
A randomised double-blind trial of phenylephrine and metaraminol infusions for prevention of hypotension during spinal and combined spinal-epidural anaesthesia for elective caesarean section.
Topics: Acid-Base Equilibrium; Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthesia, Spinal; Ces | 2017 |
Serum oxytocin concentrations in elective caesarean delivery: a randomized comparison of three infusion regimens.
Topics: Adult; Blood Pressure; Cesarean Section; Chromatography, Affinity; Delivery, Obstetric; Double-Blind | 2011 |
Prophylactic i.v. metaraminol during spinal anesthesia for elective Cesarean delivery.
Topics: Adrenergic alpha-Agonists; Adult; Anesthesia, Spinal; Blood Pressure; Cesarean Section; Elective Sur | 2003 |
Comparison of metaraminol and ephedrine infusions for maintaining arterial pressure during spinal anesthesia for elective cesarean section.
Topics: Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Apgar Score; Blood Gas Analysis; Blood Pressure; | 2001 |
Metaraminol infusion for maintenance of arterial blood pressure during spinal anesthesia for cesarean delivery: the effect of a crystalloid bolus.
Topics: Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Blood Pressure; Cesarean Section; Female; Hemody | 2001 |
Clinical evaluation of new therapeutic concepts in septic shock.
Topics: Abortion, Septic; Clinical Trials as Topic; Female; Heparin; Humans; Metaraminol; Phenoxybenzamine; | 1966 |
32 other studies available for metaraminol and Pregnancy
| Article | Year |
|---|---|
Which vasopressor for caesarean section?
Topics: Anesthesia, Obstetrical; Cesarean Section; Ephedrine; Female; Humans; Hypotension; Metaraminol; Phen | 2009 |
SEPTIC ABORTION WITH BACTEREMIC SHOCK.
Topics: Abortion, Septic; Chloramphenicol; Female; Humans; Hydrocortisone; Metaraminol; Norepinephrine; Oxyg | 1963 |
[SEPTIC SHOCK IN ABORTION].
Topics: Abortion, Induced; Abortion, Septic; Abortion, Therapeutic; Anti-Bacterial Agents; Antibiotics, Anti | 1963 |
[SEVERE ALLERGIC SHOCK AFTER PENICILLIN INJECTION].
Topics: Anaphylaxis; Epinephrine; Female; Humans; Injections; Metaraminol; Penicillins; Pregnancy; Puerperal | 1964 |
CLOSTRIDIUM WELCHII INFECTION IN GYNAECOLOGY.
Topics: Abortion, Criminal; Abortion, Induced; Abortion, Spontaneous; Anti-Bacterial Agents; Antitoxins; Blo | 1964 |
ARTERIAL CARBON DIOXIDE AND OXYGEN TENSIONS DURING SPINAL BLOCK.
Topics: Anesthesia, Conduction; Anesthesia, Obstetrical; Anesthesia, Spinal; Blood Gas Analysis; Carbon Diox | 1965 |
[CLINICAL STUDY OF A NEW SYNTHETIC SYMPATHOMIMETIC IN OBSTETRICS AND GYNECOLOGY].
Topics: Female; Gynecology; Humans; Injections, Intramuscular; Injections, Intravenous; Metaraminol; Obstetr | 1964 |
A prospective comparison of vasopressor requirement and hemodynamic changes during spinal anesthesia for cesarean delivery in patients with multiple gestation versus singleton pregnancy.
Topics: Adult; Anesthesia, Spinal; Blood Pressure; Cesarean Section; Cohort Studies; Female; Humans; Infant, | 2007 |
Myocardial infarction induced by metaraminol bitartrate (aramine).
Topics: Abortion, Spontaneous; Adult; Female; Humans; Metaraminol; Myocardial Infarction; Pregnancy; Shock | 1966 |
Pregnancy and ephedrine increase the release of nitric oxide in ovine uterine arteries.
Topics: Animals; Arginine; Arteries; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibit | 1996 |
A complication with the use of metaraminol in obstetric anaesthesia.
Topics: Anesthesia, Obstetrical; Blood Pressure; Female; Humans; Metaraminol; Pregnancy; Sympathomimetics; V | 2000 |
Maturation of the adrenal medulla--IV. Effects of morphine.
Topics: Adrenal Medulla; Aging; Animals; Animals, Newborn; Body Weight; Catecholamines; Dopamine beta-Hydrox | 1975 |
Sympatho-adrenal development in perinatally addicted rats.
Topics: Adrenal Medulla; Animals; Animals, Newborn; Catecholamines; Dopamine beta-Hydroxylase; Enzyme Induct | 1975 |
Eisenmenger syndrome in pregnancy.
Topics: Anticoagulants; Eisenmenger Complex; Female; Humans; Infant, Newborn; Male; Metaraminol; Oximetry; P | 1992 |
The vascular mechanism of ephedrine's beneficial effect on uterine perfusion during pregnancy.
Topics: Animals; Endothelium, Vascular; Ephedrine; Female; Metaraminol; Muscle, Smooth, Vascular; Potassium | 1992 |
Endotoxic shock.
Topics: Abortion, Septic; Animals; Anti-Bacterial Agents; Bacterial Infections; Blood Coagulation; Catechola | 1972 |
Abortion complicated by Clostridium perfringens infection.
Topics: Abortion, Septic; Acute Kidney Injury; Antitoxins; Chloramphenicol; Clostridium Infections; Clostrid | 1971 |
Use of the guinea-pig foetal placenta, perfused in situ, as a model to study the placental transfer of pharmacological substances.
Topics: Acid-Base Equilibrium; Animals; Antipyrine; Blood Pressure; Female; Guinea Pigs; Maternal-Fetal Exch | 1973 |
The action of vasopressors on isolated uterine arteries.
Topics: Adult; Animals; Arteries; Carbon Dioxide; Dopamine; Dose-Response Relationship, Drug; Ephedrine; Epi | 1974 |
Cardiovascular collapse unrelated to anaesthesia. An undiagnosed ectopic pregnancy.
Topics: Adult; Anesthesia, General; Blood Transfusion; Curettage; Dilatation; Female; Humans; Hypotension; K | 1974 |
Effects of equipotent ephedrine, metaraminol, mephentermine, and methoxamine on uterine blood flow in the pregnant ewe.
Topics: Acid-Base Equilibrium; Anesthesia, Local; Anesthesia, Obstetrical; Anesthesia, Spinal; Animals; Bloo | 1974 |
Toxic and antifertility effects of quinacrine hydrochloride in rats.
Topics: Animals; Atrophy; Autopsy; Colonic Diseases; Dose-Response Relationship, Drug; Drug Synergism; Embry | 1974 |
Some properties of noradrenaline uptake in non-innervated vascular smooth muscle.
Topics: Cocaine; Female; Histocytochemistry; Humans; In Vitro Techniques; Metaraminol; Microscopy, Fluoresce | 1974 |
An evaluation of vasopressor therapy for maternal hypotension during spinal anesthesia.
Topics: Anesthesia, Spinal; Animals; Cardiac Output; Ephedrine; Female; Hypotension; Mephentermine; Metarami | 1970 |
Vasopressors in obstetrics. 3. Fetal effects of metaraminol infusion during obstetric spinal hypotension.
Topics: Anesthesia, Spinal; Animals; Arteries; Blood; Blood Circulation; Blood Flow Velocity; Blood Gas Anal | 1970 |
The influence of blood flow and hypoxia on free alpha-amino nitrogen transfer across the placental membrane.
Topics: Amines; Animals; Antipyrine; Biological Transport, Active; Blood Pressure; Female; Fetus; Guinea Pig | 1970 |
[The choice of the pressor drug in hypotension caused by peridural anesthesia. Observations with methoxamine, metaraminol and mephentermine].
Topics: Adult; Aged; Anesthesia, Conduction; Anesthesia, Spinal; Cesarean Section; Female; Humans; Hypotensi | 1967 |
Inferior vena caval occlusion in late pregnancy and its importance in anesthesia.
Topics: Anesthesia, Spinal; Cesarean Section; Female; Humans; Hypotension; Metaraminol; Methods; Pregnancy; | 1968 |
Spinal shock and fetal oxygenation.
Topics: Anesthesia, Spinal; Animals; Blood Circulation; Blood Pressure; Cesarean Section; Female; Fetus; Inj | 1965 |
Bacterial shock in obstetrics and gynecology; with emphasis on the surgical management of septic abortion.
Topics: Abortion, Septic; Adult; Anti-Bacterial Agents; Female; Humans; Hysterectomy; Metaraminol; Middle Ag | 1966 |
Septic shock in obstetrics and gynecology. An evaluation of metaraminol therapy.
Topics: Abortion, Septic; Adolescent; Adult; Aged; Dexamethasone; Female; Genital Diseases, Female; Genital | 1966 |
Effects of autonomic blockade with spinal anesthesia on uterine and fetal hemodynamics and oxygen consumption in the sheep.
Topics: Anesthesia, Obstetrical; Animals; Female; Fetus; Hemodynamics; Metaraminol; Oxygen Consumption; Preg | 1966 |