metaraminol has been researched along with Muscle Contraction in 21 studies
Metaraminol: A sympathomimetic agent that acts predominantly at alpha-1 adrenergic receptors. It has been used primarily as a vasoconstrictor in the treatment of HYPOTENSION.
metaraminol : A member of the class of phenylethanolamines that is 2-amino-1-phenylethanol substituted by a methyl group at position 2 and a phenolic hydroxy group at position 1. A sympathomimetic agent , it is used in the treatment of hypotension.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
Excerpt | Relevance | Reference |
---|---|---|
" In isolated aortic rings the dose-response curve for (-)metaraminol was not parallel to that of (-)epinephrine, (-)norepinephrine or (-)phenylephrine." | 1.27 | Heterogeneity of alpha 1 receptors associated with vascular smooth muscle: evidence from functional and ligand binding studies. ( Babich, M; Butler, BT; Pedigo, NW; Piascik, MT, 1987) |
"Reserpine was used in 0." | 1.26 | Effects of noradrenaline and metaraminol on isolated aortic strips and auricles obtained from untreated and reserpine-treated rabbits. ( Qayum, A; Tayyaba, B; Yusuf, SM, 1979) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 21 (100.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
LEONARD, E | 1 |
SARNOFF, SJ | 1 |
Johns, A | 4 |
Steger, RW | 1 |
Bartke, A | 1 |
Kitamura, S | 1 |
Ishihara, Y | 1 |
Kosaka, K | 1 |
Ohkawa, H | 1 |
Paton, DM | 3 |
Golko, DS | 1 |
Lauzon, PA | 1 |
Finkbeiner, AE | 1 |
Bissada, NK | 1 |
Welch, L | 1 |
Tayyaba, B | 1 |
Qayum, A | 1 |
Yusuf, SM | 1 |
Marvola, M | 1 |
Friström, S | 1 |
Klinge, E | 1 |
Halmekoski, J | 1 |
Babich, M | 1 |
Pedigo, NW | 1 |
Butler, BT | 1 |
Piascik, MT | 1 |
Schrold, J | 1 |
Nedergaard, OA | 1 |
Kones, RJ | 1 |
Ghouri, MS | 1 |
Haley, TJ | 1 |
Caldwell, RW | 1 |
Goldberg, LI | 1 |
Gagnon, DJ | 1 |
Alabaster, VA | 1 |
Bakhle, YS | 1 |
Puri, PS | 1 |
Bing, RJ | 1 |
Swamy, VC | 1 |
Tye, A | 2 |
Lapidus, JB | 1 |
Patil, PN | 2 |
Patel, DG | 1 |
Stone, CA | 1 |
Stavorski, JM | 1 |
Ludden, CT | 1 |
Wenger, HC | 1 |
Torchiana, ML | 1 |
2 reviews available for metaraminol and Muscle Contraction
Article | Year |
---|---|
Uropharmacology: VIII. Sympathomimetic agents.
Topics: Animals; Cats; Dogs; Dopamine; Drug Interactions; Ephedrine; Epinephrine; Humans; Isoproterenol; Mal | 1978 |
Cardiogenic shock: therapeutic implications of altered myocardial energy balance.
Topics: Adrenergic alpha-Antagonists; Aerobiosis; Anaerobiosis; Angiotensin II; Assisted Circulation; Blood | 1974 |
1 trial available for metaraminol and Muscle Contraction
Article | Year |
---|---|
Effect of drugs on myocardial contractility in the intact dog and in experimental myocardial infarction.
Topics: Animals; Clinical Trials as Topic; Dogs; Heart; Isoproterenol; Metaraminol; Methoxamine; Muscle Cont | 1968 |
18 other studies available for metaraminol and Muscle Contraction
Article | Year |
---|---|
Effect of aramine-induced smooth muscle contraction on length-tension diagrams of venous strips.
Topics: Metaraminol; Muscle Contraction; Sympathomimetics; Veins | 1957 |
The effects of photoperiod on the responses of the hamster vas deferens to nerve stimulation.
Topics: Animals; Atrophy; Catecholamines; Cricetinae; Electric Stimulation; In Vitro Techniques; Light; Male | 1983 |
Effect of prostaglandins E1 and E2 on rabbit pulmonary artery and aorta strips.
Topics: Animals; Aorta; Dose-Response Relationship, Drug; Male; Metaraminol; Muscle Contraction; Prostagland | 1980 |
Evidences for alpha excitatory action of catecholamines on the electrical activity of the guinea-pig stomach.
Topics: Alprenolol; Animals; Catecholamines; Electrophysiology; Epinephrine; Female; Guinea Pigs; In Vitro T | 1976 |
The effect of caesium on adrenergic transmission in rabbit vas deferens.
Topics: Action Potentials; Animals; Cesium; Electric Stimulation; Guanethidine; In Vitro Techniques; Indomet | 1975 |
The potentiating effects of 4-aminopyridine on adrenergic transmission in the rabbit vas deferens.
Topics: Animals; Electric Stimulation; In Vitro Techniques; Male; Metaraminol; Muscle Contraction; Norepinep | 1976 |
Effects of noradrenaline and metaraminol on isolated aortic strips and auricles obtained from untreated and reserpine-treated rabbits.
Topics: Animals; Drug Interactions; Female; Heart Rate; In Vitro Techniques; Male; Metaraminol; Muscle Contr | 1979 |
Effect of rubidium on responses of rabbit vas deferens to transmural stimulation and to noradrenaline.
Topics: Animals; Electric Stimulation; In Vitro Techniques; Indomethacin; Male; Metaraminol; Muscle Contract | 1976 |
The effect of some sympathomimetic amines and their acetyl derivatives on the isolated bull retractor penis muscle.
Topics: Amphetamines; Animals; Cattle; Cocaine; Dose-Response Relationship, Drug; Ephedrine; Epinephrine; In | 1976 |
Heterogeneity of alpha 1 receptors associated with vascular smooth muscle: evidence from functional and ligand binding studies.
Topics: Animals; Aorta; Dose-Response Relationship, Drug; Epinephrine; Male; Metaraminol; Microsomes; Muscle | 1987 |
Letter: Release of (3H)noradrenaline and (3H)metaraminol from rabbit pulmonary artery in vitro.
Topics: Animals; Electric Stimulation; In Vitro Techniques; Metaraminol; Muscle Contraction; Norepinephrine; | 1973 |
In vitro evaluation of a series of sympathomimetic amines and the beta-adrenergic blocking properties of cyclopentamine.
Topics: Animals; Cyclopentanes; Female; Ileum; In Vitro Techniques; Isoproterenol; Metaraminol; Methoxamine; | 1969 |
An evaluation of the vasodilation produced by mephentermine and certain other sympathomimetic amines.
Topics: Animals; Arteries; Atropine; Blood Flow Velocity; Chemical Phenomena; Chemistry; Dextroamphetamine; | 1970 |
Contraction of the rat colon by sympathomimetic amines: effect of methysergide and 5-HT desensitization.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Colon; Drug Inter | 1972 |
The removal of noradrenaline in the pulmonary circulation of rat isolated lungs.
Topics: Animals; Aorta; Cocaine; Dogs; In Vitro Techniques; Lung; Metaraminol; Muscle Contraction; Norepinep | 1973 |
Steric aspects of adrenergic drugs. 3. Norepinephrine potentiating effects of isomers of sympathomimetic amine in rat vas deferens and atria.
Topics: Amines; Amino Alcohols; Amphetamine; Animals; Cocaine; Dopamine; Drug Synergism; Ephedrine; Heart At | 1969 |
Steric aspects of adrenergic drugs. XIV. Actions and interactions of "indirectly" acting L(+)-isomers and desoxy derivatives of sympathomimetic amines.
Topics: Amines; Amino Alcohols; Amphetamine; Animals; Blood Flow Velocity; Dopamine; Ephedrine; Heart; Heart | 1969 |
Some direct and indirect sympathomimetic actions of metaraminol.
Topics: Animals; Blood Pressure; Cats; Dogs; Guinea Pigs; Heart; In Vitro Techniques; Metaraminol; Muscle Co | 1966 |