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metaraminol and Muscle Contraction

metaraminol has been researched along with Muscle Contraction in 21 studies

Metaraminol: A sympathomimetic agent that acts predominantly at alpha-1 adrenergic receptors. It has been used primarily as a vasoconstrictor in the treatment of HYPOTENSION.
metaraminol : A member of the class of phenylethanolamines that is 2-amino-1-phenylethanol substituted by a methyl group at position 2 and a phenolic hydroxy group at position 1. A sympathomimetic agent , it is used in the treatment of hypotension.

Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

Research Excerpts

ExcerptRelevanceReference
" In isolated aortic rings the dose-response curve for (-)metaraminol was not parallel to that of (-)epinephrine, (-)norepinephrine or (-)phenylephrine."1.27Heterogeneity of alpha 1 receptors associated with vascular smooth muscle: evidence from functional and ligand binding studies. ( Babich, M; Butler, BT; Pedigo, NW; Piascik, MT, 1987)
"Reserpine was used in 0."1.26Effects of noradrenaline and metaraminol on isolated aortic strips and auricles obtained from untreated and reserpine-treated rabbits. ( Qayum, A; Tayyaba, B; Yusuf, SM, 1979)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199021 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
LEONARD, E1
SARNOFF, SJ1
Johns, A4
Steger, RW1
Bartke, A1
Kitamura, S1
Ishihara, Y1
Kosaka, K1
Ohkawa, H1
Paton, DM3
Golko, DS1
Lauzon, PA1
Finkbeiner, AE1
Bissada, NK1
Welch, L1
Tayyaba, B1
Qayum, A1
Yusuf, SM1
Marvola, M1
Friström, S1
Klinge, E1
Halmekoski, J1
Babich, M1
Pedigo, NW1
Butler, BT1
Piascik, MT1
Schrold, J1
Nedergaard, OA1
Kones, RJ1
Ghouri, MS1
Haley, TJ1
Caldwell, RW1
Goldberg, LI1
Gagnon, DJ1
Alabaster, VA1
Bakhle, YS1
Puri, PS1
Bing, RJ1
Swamy, VC1
Tye, A2
Lapidus, JB1
Patil, PN2
Patel, DG1
Stone, CA1
Stavorski, JM1
Ludden, CT1
Wenger, HC1
Torchiana, ML1

Reviews

2 reviews available for metaraminol and Muscle Contraction

ArticleYear
Uropharmacology: VIII. Sympathomimetic agents.
    Urology, 1978, Volume: 11, Issue:5

    Topics: Animals; Cats; Dogs; Dopamine; Drug Interactions; Ephedrine; Epinephrine; Humans; Isoproterenol; Mal

1978
Cardiogenic shock: therapeutic implications of altered myocardial energy balance.
    Angiology, 1974, Volume: 25, Issue:5

    Topics: Adrenergic alpha-Antagonists; Aerobiosis; Anaerobiosis; Angiotensin II; Assisted Circulation; Blood

1974

Trials

1 trial available for metaraminol and Muscle Contraction

ArticleYear
Effect of drugs on myocardial contractility in the intact dog and in experimental myocardial infarction.
    The American journal of cardiology, 1968, Volume: 21, Issue:6

    Topics: Animals; Clinical Trials as Topic; Dogs; Heart; Isoproterenol; Metaraminol; Methoxamine; Muscle Cont

1968

Other Studies

18 other studies available for metaraminol and Muscle Contraction

ArticleYear
Effect of aramine-induced smooth muscle contraction on length-tension diagrams of venous strips.
    Circulation research, 1957, Volume: 5, Issue:2

    Topics: Metaraminol; Muscle Contraction; Sympathomimetics; Veins

1957
The effects of photoperiod on the responses of the hamster vas deferens to nerve stimulation.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 224, Issue:1

    Topics: Animals; Atrophy; Catecholamines; Cricetinae; Electric Stimulation; In Vitro Techniques; Light; Male

1983
Effect of prostaglandins E1 and E2 on rabbit pulmonary artery and aorta strips.
    Advances in prostaglandin and thromboxane research, 1980, Volume: 7

    Topics: Animals; Aorta; Dose-Response Relationship, Drug; Male; Metaraminol; Muscle Contraction; Prostagland

1980
Evidences for alpha excitatory action of catecholamines on the electrical activity of the guinea-pig stomach.
    The Japanese journal of physiology, 1976, Volume: 26, Issue:1

    Topics: Alprenolol; Animals; Catecholamines; Electrophysiology; Epinephrine; Female; Guinea Pigs; In Vitro T

1976
The effect of caesium on adrenergic transmission in rabbit vas deferens.
    Canadian journal of physiology and pharmacology, 1975, Volume: 53, Issue:3

    Topics: Action Potentials; Animals; Cesium; Electric Stimulation; Guanethidine; In Vitro Techniques; Indomet

1975
The potentiating effects of 4-aminopyridine on adrenergic transmission in the rabbit vas deferens.
    European journal of pharmacology, 1976, Volume: 38, Issue:1

    Topics: Animals; Electric Stimulation; In Vitro Techniques; Male; Metaraminol; Muscle Contraction; Norepinep

1976
Effects of noradrenaline and metaraminol on isolated aortic strips and auricles obtained from untreated and reserpine-treated rabbits.
    Canadian journal of physiology and pharmacology, 1979, Volume: 57, Issue:2

    Topics: Animals; Drug Interactions; Female; Heart Rate; In Vitro Techniques; Male; Metaraminol; Muscle Contr

1979
Effect of rubidium on responses of rabbit vas deferens to transmural stimulation and to noradrenaline.
    European journal of pharmacology, 1976, Volume: 35, Issue:1

    Topics: Animals; Electric Stimulation; In Vitro Techniques; Indomethacin; Male; Metaraminol; Muscle Contract

1976
The effect of some sympathomimetic amines and their acetyl derivatives on the isolated bull retractor penis muscle.
    Acta pharmacologica et toxicologica, 1976, Volume: 39, Issue:3

    Topics: Amphetamines; Animals; Cattle; Cocaine; Dose-Response Relationship, Drug; Ephedrine; Epinephrine; In

1976
Heterogeneity of alpha 1 receptors associated with vascular smooth muscle: evidence from functional and ligand binding studies.
    Life sciences, 1987, Aug-10, Volume: 41, Issue:6

    Topics: Animals; Aorta; Dose-Response Relationship, Drug; Epinephrine; Male; Metaraminol; Microsomes; Muscle

1987
Letter: Release of (3H)noradrenaline and (3H)metaraminol from rabbit pulmonary artery in vitro.
    The Journal of pharmacy and pharmacology, 1973, Volume: 25, Issue:12

    Topics: Animals; Electric Stimulation; In Vitro Techniques; Metaraminol; Muscle Contraction; Norepinephrine;

1973
In vitro evaluation of a series of sympathomimetic amines and the beta-adrenergic blocking properties of cyclopentamine.
    Journal of pharmaceutical sciences, 1969, Volume: 58, Issue:7

    Topics: Animals; Cyclopentanes; Female; Ileum; In Vitro Techniques; Isoproterenol; Metaraminol; Methoxamine;

1969
An evaluation of the vasodilation produced by mephentermine and certain other sympathomimetic amines.
    The Journal of pharmacology and experimental therapeutics, 1970, Volume: 172, Issue:2

    Topics: Animals; Arteries; Atropine; Blood Flow Velocity; Chemical Phenomena; Chemistry; Dextroamphetamine;

1970
Contraction of the rat colon by sympathomimetic amines: effect of methysergide and 5-HT desensitization.
    European journal of pharmacology, 1972, Volume: 17, Issue:3

    Topics: Acetylcholine; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Colon; Drug Inter

1972
The removal of noradrenaline in the pulmonary circulation of rat isolated lungs.
    British journal of pharmacology, 1973, Volume: 47, Issue:2

    Topics: Animals; Aorta; Cocaine; Dogs; In Vitro Techniques; Lung; Metaraminol; Muscle Contraction; Norepinep

1973
Steric aspects of adrenergic drugs. 3. Norepinephrine potentiating effects of isomers of sympathomimetic amine in rat vas deferens and atria.
    Archives internationales de pharmacodynamie et de therapie, 1969, Volume: 182, Issue:1

    Topics: Amines; Amino Alcohols; Amphetamine; Animals; Cocaine; Dopamine; Drug Synergism; Ephedrine; Heart At

1969
Steric aspects of adrenergic drugs. XIV. Actions and interactions of "indirectly" acting L(+)-isomers and desoxy derivatives of sympathomimetic amines.
    Archives internationales de pharmacodynamie et de therapie, 1969, Volume: 182, Issue:1

    Topics: Amines; Amino Alcohols; Amphetamine; Animals; Blood Flow Velocity; Dopamine; Ephedrine; Heart; Heart

1969
Some direct and indirect sympathomimetic actions of metaraminol.
    Archives internationales de pharmacodynamie et de therapie, 1966, Volume: 161, Issue:1

    Topics: Animals; Blood Pressure; Cats; Dogs; Guinea Pigs; Heart; In Vitro Techniques; Metaraminol; Muscle Co

1966